EudraCT Number: 2019-002935-27 Sponsor Protocol Number: ADVL1712 Start Date: 2021-05-21
Sponsor Name: National Cancer Institute
Full Title: A Feasibility Trial of MLN4924 (Pevonedistat,TAK924) Given in Combination With Azacitidine, Fludarabine, and Cytarabine, in Children, Adolescents, and Young Adults With Relapsed or Refractory Acute...
Medical condition: This trial studies the side effects and how well pevonedistat, azacitidine, fludarabine phosphate, and cytarabine work in treating patients with acute myeloid leukemia that has come back or has not...
Disease: Version SOC Term Classification Code Term Level
20.1 100000004864 10024330 Leukemia acute LLT
21.0 100000004864 10024349 Leukemia myeloid LLT
21.0 100000004864 10028534 Myelodysplastic syndrome NOS LLT
Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
Trial protocol: Outside EU/EEA
Trial results: (No results available)

EudraCT Number: 2019-002934-35 Sponsor Protocol Number: ADVL1615 Start Date: 2021-05-21
Sponsor Name: Children's Oncology Group
Full Title: A Phase 1 Study of Pevonedistat (MLN4924, IND# 136078) a NEDD8 Activating Enzyme (NAE) Inhibitor, in Combination With Temozolomide and Irinotecan in Pediatric Patients With Recurrent or Refractory ...
Medical condition: This trial studies the side effects and best dose of pevonedistat when given together with irinotecan and temozolomide in treating patients with solid tumors or lymphoma that have come back after a...
Disease: Version SOC Term Classification Code Term Level
21.0 100000004864 10049516 Malignant tumor LLT
Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
Trial protocol: Outside EU/EEA
Trial results: (No results available)
EudraCT Number: 2020-001927-15 Sponsor Protocol Number: TV48574-AS-20031 Start Date: 2021-02-22
Sponsor Name: Teva Branded Pharmaceutical Products R&D, Inc.
Full Title: A 16-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Proof-of-Concept Study to Evaluate the Efficacy and Safety of TEV-48574 in Adults with T2-low/non-T2 Severe Uncontrolled Asthma
Medical condition: T2-low/non-T2 Severe Uncontrolled Asthma
Disease: Version SOC Term Classification Code Term Level
20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10003553 Asthma PT
Population Age: Adults, Elderly Gender: Male, Female
Trial protocol: DE (Ongoing) BG (Ongoing) CZ (Ongoing)
Trial results: (No results available)

EudraCT Number: 2019-001881-14 Sponsor Protocol Number: 20072650 Start Date: 2021-03-19
Sponsor Name: Department of Endocrinology and Internal Medicine, Aarhus University Hospital
Full Title: Endocrine, cardiovascular, pharmacologic and physiologic aspects of sex hormone treatment in Turner syndrome - project part 1
Medical condition: Ovarian dysgenesis and related hypogonadism causes by Turner syndrome
Disease: Version SOC Term Classification Code Term Level
20.0 10010331 - Congenital, familial and genetic disorders 10045181 Turner's syndrome PT
Population Age: Adults Gender: Female
Trial protocol: DK (Ongoing)
Trial results: (No results available)
EudraCT Number: 2020-001314-37 Sponsor Protocol Number: BUL-8/EEA Start Date: 2021-04-26
Sponsor Name: Dr. Falk Pharma GmbH
Full Title: Double-blind, double-dummy, randomized, parallel-group, non-inferiority phase III trial on the efficacy and tolerability of 2 mg once daily vs. 1 mg twice daily budesonide orodispersible tablets fo...
Medical condition: eosinophilic esophagitis
Disease: Version SOC Term Classification Code Term Level
20.1 10017947 - Gastrointestinal disorders 10064212 Eosinophilic oesophagitis PT
Population Age: Adults, Elderly Gender: Male, Female
Trial protocol: DE (Ongoing)
Trial results: (No results available)

EudraCT Number: 2019-004934-40 Sponsor Protocol Number: 20072651 Start Date: 2021-03-19
Sponsor Name: Department of Endocrinology and Internal Medicine, Aarhus University Hospital
Full Title: Endocrine, cardiovascular, pharmacologic and physiologic aspects of sex hormone treatment in Turner syndrome - project part B
Medical condition: Ovarian dysgenesis and related hypogonadism causes by Turner syndrome
Disease: Version SOC Term Classification Code Term Level
20.0 10010331 - Congenital, familial and genetic disorders 10045181 Turner's syndrome PT
Population Age: Adults Gender: Female
Trial protocol: DK (Ongoing)
Trial results: (No results available)
EudraCT Number: 2019-002282-35 Sponsor Protocol Number: rh-NGF Start Date: 2020-05-13
Sponsor Name: FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS UNIVERSITA' CATTOLICA DEL SACRO CUORE
Full Title: Nerve growth factor in pediatric severe traumatic brain injury : translational and clinical studies on a candidate biomarker and therapeutic drug
Medical condition: Persistent unresponsive wakefulness syndrome (UWS)
Disease: Version SOC Term Classification Code Term Level
20.1 100000004863 10049615 Late effects of head trauma LLT
Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
Trial protocol: IT (Ongoing)
Trial results: (No results available)

EudraCT Number: 2010-023757-11 Sponsor Protocol Number: myDC/pDCinstageIIImelanoma Start Date: 2014-11-06
Sponsor Name: Radboud University Nijmegen Medical Centre
Full Title: Myeloid and plasmacytoid blood dendritic cells for immunotherapy of stage III melanoma patients scheduled for radical lymph node dissection
Medical condition: melanoma patients with regional lymph node metastases (stage III)
Disease: Version SOC Term Classification Code Term Level
Population Age: Adults, Elderly Gender: Male, Female
Trial protocol: NL (Completed)
Trial results: (No results available)
EudraCT Number: 2020-005518-16 Sponsor Protocol Number: U3P Start Date: 2021-05-10
Sponsor Name: Universitätsklinikum Erlangen
Full Title: U3P study - Upadacitinib in Psoriatic Arthritis Pain Processing
Medical condition: Psoriatic arthritis
Disease: Version SOC Term Classification Code Term Level
21.1 10028395 - Musculoskeletal and connective tissue disorders 10037162 Psoriatic arthropathy PT
Population Age: Adults, Elderly Gender: Male, Female
Trial protocol: DE (Ongoing)
Trial results: (No results available)

EudraCT Number: 2016-004159-56 Sponsor Protocol Number: MERISUDD Start Date: 2017-10-12
Sponsor Name: DIPARTIMENTO DI MEDICINA CLINICA E CHIRURGIA - UNIVERSITÀ DEGLI STUDI DI NAPOLI FEDERICO II
Full Title: Efficacy and safety of mesalazine, rifaximin, alone or as extemporary combination, in the treatment of symptomatic uncomplicated diverticular disease of colon: multi-centre, randomised, double-blin...
Medical condition: Treatment of symptomatic uncomplicated diverticular colon disease (SUDD)
Disease: Version SOC Term Classification Code Term Level
20.0 10021881 - Infections and infestations 10013538 Diverticulitis PT
Population Age: Adults, Elderly Gender: Male, Female
Trial protocol: IT (Ongoing)
Trial results: (No results available)