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Mental Effort During Low Load Resistance Training in Older Adults

6 juillet 2026 mis à jour par: Garrett Hester, Kennesaw State University

The Effect of Maximal Mental Effort During Resistance Training on Physical Function and Motor Unit Behavior in Older Adults

The goal of this clinical trial is to determine the effect of maximal mental effort combined with low-intensity resistance training on strength and neuromuscular function in older adults. The main questions it aims to answer are:

  • Does low-intensity resistance training in combination with maximal mental effort increase strength more than low intensity resistance training alone?
  • Does low-intensity resistance training in combination with maximal mental effort improve neuromuscular function more than low intensity resistance training alone?

Participants will be randomly assigned to 1 of 3 groups:

  • Low intensity resistance training
  • Low intensity resistance training with maximal mental effort
  • Control Researchers will compare groups to determine differences in changes in strength, neuromuscular function, and body composition.

Aperçu de l'étude

Statut

Recrutement

Les conditions

Intervention / Traitement

Description détaillée

Participants in both training groups will perform 8 weeks of low intensity, whole-body resistance training. Participants in the control group will participate in all testing procedures but not perform any training. Participants from all groups will be instructed to otherwise maintain their normal physical activity levels and dietary habits.

All training sessions will be supervised by research personnel at a Kennesaw State University fitness center. Participants will complete 2 training sessions per week for 8 weeks. Each training session will last about 45-60 minutes and consist of 5 exercises, including both multi-joint (leg press, chest press, back row) and single-joint (knee extension, bicep curl) exercises. Participants will perform 2 sets of 15 repetitions for each exercise for the first 2 weeks, then volume will be increased by progressing to 3 sets for the remaining 6 weeks. There will be a 60-second rest interval between sets and a similar tempo will be used between groups.

Both training groups will perform the same training protocol, but participants in the maximal mental effort group will mentally urge their muscles to contract maximally during each repetition. That is, despite using a low intensity, participants will imagine the feeling of maximal muscle contraction of the primary muscles during each repetition.

Several measures of strength, neuromuscular function, physical function, and body composition will be measured before and after the training or control period.

Type d'étude

Interventionnel

Inscription (Estimé)

75

Phase

  • N'est pas applicable

Contacts et emplacements

Cette section fournit les coordonnées de ceux qui mènent l'étude et des informations sur le lieu où cette étude est menée.

Coordonnées de l'étude

  • Nom: Garrett Hester Professor of Exercise Science
  • Numéro de téléphone: 470-578-4267
  • E-mail: ghester4@kennesaw.edu

Lieux d'étude

  • États-Unis
    • Georgia
      • Kennesaw, Georgia, États-Unis, 30144
        • Recrutement
        • Kennesaw State University
        • Contact:

Critères de participation

Les chercheurs recherchent des personnes qui correspondent à une certaine description, appelée critères d'éligibilité. Certains exemples de ces critères sont l'état de santé général d'une personne ou des traitements antérieurs.

Critère d'éligibilité

Âges éligibles pour étudier

  • Adulte plus âgé

Accepte les volontaires sains

Oui

La description

Inclusion Criteria:

  • Body mass index between 18.5 - 33 kg·m2
  • No structured physical activity in past 2 years
  • Any unstable condition contradicting exercise
  • Independently walk with or without assistive device
  • No significant cognitive impairment

Exclusion Criteria:

  • Score of 22 or lower on Montreal Cognitive Assessment
  • Missing more than 3 training sessions (training groups only)
  • Pacemaker
  • Unstable angina
  • Symptomatic heart failure
  • Uncontrolled arrythmias
  • Uncontrolled hypertension (greater or equal to 160/90)
  • Myocardial infarction in the past 6 months
  • Uncontrolled type 2 diabetes
  • Type 1 diabetes
  • Severe or unstable pulmonary conditions,
  • Currently on supplemental oxygen therapy
  • Severe hearing loss or visual impairment
  • Alzheimer's Disease or significant cognitive impairment
  • Stroke in the past 6 months or ongoing stroke-induced motor impairment
  • Any neurological (e.g., Parkinson's) condition affecting motor control
  • Undergoing chemotherapy
  • Surgery in past 6 months
  • Musculoskeletal injury in the past 6 months
  • Terminal illness
  • Stage 3 or greater chronic kidney disease

Plan d'étude

Cette section fournit des détails sur le plan d'étude, y compris la façon dont l'étude est conçue et ce que l'étude mesure.

Comment l'étude est-elle conçue ?

Détails de conception

  • Objectif principal: Autre
  • Répartition: Randomisé
  • Modèle interventionnel: Affectation parallèle
  • Masquage: Seul

Armes et Interventions

Groupe de participants / Bras
Intervention / Traitement
Aucune intervention: Contrôle
Ce groupe n'effectuera aucun entraînement et maintiendra son niveau régulier d'activité physique.
Expérimental: Low Intensity Resistance Training
This group will perform low intensity, whole-body resistance training.
Comportemental: Low Intensity Resistance Training
This training intervention will be 8 weeks of low intensity resistance training, including whole-body and isolated muscle exercises.
Expérimental: Low Intensity Resistance Training with Maximal Mental Effort
This group will perform low intensity, whole-body resistance training with maximal mental effort during muscle contraction.
Comportemental: Low Intensity Resistance Training with Maximal Mental Effort
This training intervention will be 8 weeks of low intensity resistance training, including whole-body and isolated muscle exercises, where participants will perform maximal mental effort by imagining maximal muscle contraction during each exercise.

Que mesure l'étude ?

Principaux critères de jugement

Mesure des résultats
Description de la mesure
Délai
Change in isokinetic strength of the knee extensors at 60 degrees per second
Délai: Baseline, Week 8
Dynamic strength of the knee extensors contracting at a constant velocity
Baseline, Week 8

Mesures de résultats secondaires

Mesure des résultats
Description de la mesure
Délai
Change in isokinetic knee extensor muscle activation as measured by electromyography amplitude
Délai: Baseline, Week 8
Electromyography root mean square during isokinetic contraction divided by root mean square during isometric contraction
Baseline, Week 8
Change in isometric knee extensor strength as measured by newton-meters of torque
Délai: Baseline, Week 8
Isometric strength of a muscle
Baseline, Week 8
Change in knee extensor muscle activation as measured by electromyography amplitude
Délai: Baseline, Week 8
A measure of the capacity at which the muscle is activated by the nervous system
Baseline, Week 8
Change in motor unit firing rate as measured relative to the motor unit recruitment threshold
Délai: Baseline, Week 8
A measure of how nervous system input produces force output during an isometric contraction
Baseline, Week 8
Change in motor unit action potential size as measured relative to the motor unit recruitment threshold
Délai: Baseline, Week 8
A measure of how nervous system input produces force output during an isometric contraction
Baseline, Week 8
Change in handgrip strength as measured in kilograms of force
Délai: Baseline, Week 8
Upper-body strength as measured by a handgrip dynamometer
Baseline, Week 8
Change in walking speed as measured by time taken to walk 4 meters
Délai: Baseline, Week 8
Measure of lower-body physical function
Baseline, Week 8
Change in chair rise performance as measured by number of chair rises performed in 30 seconds
Délai: Baseline, Week 8
Measure of lower-body physical function
Baseline, Week 8
Change in bicep curl strength as measured by load lifted in pounds
Délai: Baseline, Week 8
Maximum dumbbell load lifted successfully throughout the range of motion of a bicep curl
Baseline, Week 8
Change in dynamic strength of the lower body muscles during the leg press as measured by load lifted in pounds for 5 repetitions
Délai: Baseline, Week 5, Week 8
Measure of dynamic strength during the leg press exercise
Baseline, Week 5, Week 8
Change in muscle composition as measured by ultrasound-derived grey-scale analysis
Délai: Baseline, Week 8
Echo-intensity value derived from grey-scale analysis is indicative of amount of non-contractile tissue in muscle
Baseline, Week 8
Change in skeletal muscle size as measured by ultrasound-derived cross-sectional area
Délai: Baseline, Week 8
Size of a muscle
Baseline, Week 8
Change in fat mass as measured by kilograms
Délai: Baseline, Week 8
Amount of fat tissue a person possesses estimated by bioelectrical impedance analysis
Baseline, Week 8
Change in fat-free mass as measured by kilograms
Délai: Baseline, Week 8
Amount of non-fat tissue a person possesses estimated by bioelectrical impedance analysis
Baseline, Week 8
Change in body fat percentage as measured by fat tissue relative to fat-free tissue
Délai: Baseline, Week 8
Relative amount of body fat a person possesses estimated by bioelectrical impedance analysis
Baseline, Week 8
Change in cognitive function as measured by the Montreal Cognitive Assessment
Délai: Baseline, Week 8
Assessment of cognitive function where 0 is the lowest score and 30 is the highest score and a higher score represents higher cognitive function.
Baseline, Week 8

Collaborateurs et enquêteurs

C'est ici que vous trouverez les personnes et les organisations impliquées dans cette étude.

Parrainer

Kennesaw State University

Dates d'enregistrement des études

Ces dates suivent la progression des dossiers d'étude et des soumissions de résultats sommaires à ClinicalTrials.gov. Les dossiers d'étude et les résultats rapportés sont examinés par la Bibliothèque nationale de médecine (NLM) pour s'assurer qu'ils répondent à des normes de contrôle de qualité spécifiques avant d'être publiés sur le site Web public.

Dates principales de l'étude

Début de l'étude (Réel)

6 juin 2026

Achèvement primaire (Estimé)

1 décembre 2027

Achèvement de l'étude (Estimé)

1 décembre 2027

Dates d'inscription aux études

Première soumission

30 juin 2026

Première soumission répondant aux critères de contrôle qualité

30 juin 2026

Première publication (Réel)

7 juillet 2026

Mises à jour des dossiers d'étude

Dernière mise à jour publiée (Réel)

8 juillet 2026

Dernière mise à jour soumise répondant aux critères de contrôle qualité

6 juillet 2026

Dernière vérification

1 juillet 2026

Plus d'information

Termes liés à cette étude

Mots clés

Termes MeSH pertinents supplémentaires

Autres numéros d'identification d'étude

  • 2026-Hester

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Informations sur les médicaments et les dispositifs, documents d'étude

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