Comparative Effects of Mulligan Bent Leg Raise Versus Spinal Mobilization With Leg Movement in Lumbar Radiculopathy
21 luglio 2026 aggiornato da: Riphah International University
Comparative Effects of Mulligan Bent Leg Raise Versus Spinal Mobilization With Leg Movement on Pain, Neural Mobility, Balance and Functional Disability in Lumbar Radiculopathy
Lumbar radiculopathy is a spinal nerve root disorder often caused by lumbar disc herniation or compression, leading to radiating leg pain, restricted movement, and functional difficulties.
This condition significantly disrupts daily activities and overall quality of life.
While medication and exercise are common treatments, manual therapy techniques are gaining recognition for their non-invasive and effective outcomes in relieving symptoms and improving patient function.
Panoramica dello studio
Stato
Reclutamento
Condizioni
Intervento / Trattamento
Descrizione dettagliata
This randomized clinical trial will be conducted in Physiotherapy outpatient department of Jinnah Hospital Lahore.
It will include 52 participants, aged 20 to 40 years, meeting clinical criteria for lumbar radiculopathy.
Participants will be selected from an outpatient physiotherapy department and assigned randomly into two equal groups.
Group A will receive the MBLR technique, while Group B will undergo the SMWLM technique.
Both interventions will be applied three times a week for four weeks under standardized protocols.
Key outcome measures include pain intensity assessed using the Numeric Pain Rating Scale (NPRS), neural mobility evaluated through the Straight Leg Raise (SLR) and Slump Test, and functional status measured using the Oswestry Disability Index (ODI), Timed Up and Go (TUG) test, and 5 Repetition Sit-to-Stand test for postural balance.
Assessments will be conducted at baseline, after 2 weeks, at 4 weeks post-intervention, and at 8-week follow-up.
Data analysis will be done by SPSS version 25.
To ensure objectivity, all assessments will be conducted while keeping the patient unaware of their group assignment.
Tipo di studio
Interventistico
Iscrizione (Stimato)
52
Fase
- Non applicabile
Contatti e Sedi
Questa sezione fornisce i recapiti di coloro che conducono lo studio e informazioni su dove viene condotto lo studio.
Contatto studio
- Nome: Samrood Akram, PhD*
- Numero di telefono: 03324806143
- Email: samrood.akram@riphah.edu.pk
Backup dei contatti dello studio
- Nome: Amna Zia, PhD*
- Numero di telefono: 03244686993
- Email: amna.zia@kemu.edu.pk
Luoghi di studio
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Punjab Province
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Lahore, Punjab Province, Pakistan, 54000
- Reclutamento
- Femwell Physiocare Woman Rehab clinic
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Contatto:
- Arooj Fatima, MS-OMPT
- Numero di telefono: 03270056769
- Email: draroohfahim@gmail.com
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Criteri di partecipazione
I ricercatori cercano persone che corrispondano a una certa descrizione, chiamata criteri di ammissibilità. Alcuni esempi di questi criteri sono le condizioni generali di salute di una persona o trattamenti precedenti.
Criteri di ammissibilità
Età idonea allo studio
- Adulto
Accetta volontari sani
No
Descrizione
Inclusion Criteria:
- Age 20 to 40 years (26)
- Diagnosed patient with Unilateral Lumbar Radiculopathy secondary to L4/L5 and L5/S1 lumbar posterolateral disc buldge confirmed on MRI (12)
- Posterolateral Lumbar Radiculopathy
Exclusion Criteria:
• Presence of red flags (e.g., cauda equina syndrome, severe neurological deficits).
- Previous spinal surgery within 1 year.
- Severe osteoporosis or vertebral fractures.
- Pregnant women.
- Systemic inflammatory or autoimmune diseases.
Piano di studio
Questa sezione fornisce i dettagli del piano di studio, compreso il modo in cui lo studio è progettato e ciò che lo studio sta misurando.
Come è strutturato lo studio?
Dettagli di progettazione
- Scopo principale: Trattamento
- Assegnazione: Randomizzato
- Modello interventistico: Assegnazione parallela
- Mascheramento: Separare
Armi e interventi
Gruppo di partecipanti / Arm |
Intervento / Trattamento |
|---|---|
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Sperimentale: Mulligan Bent Leg Raise (MBLR)
The Mulligan Bent Leg Raise (BLR) technique is a specialized physical therapy mobilization method used to relieve low back pain, reduce sciatica, and improve hamstring flexibility.
It involves applying gentle, pain-free traction while moving the leg through progressively greater ranges of hip flexion.
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Patient Position - Supine at edge of plinth
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Comparatore attivo: Spinal Mobilization with Leg Movement (SMWLM)
Spinal Mobilization with Leg Movement (SMWLM) is an advanced manual therapy technique developed as part of the Mulligan Concept.
It integrates manual joint mobilization with neurodynamic principles to treat lower back and radiating leg pain, most notably lumbar radiculopathy (sciatica)
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Patient Position - Side-lying on unaffected side near edge
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Cosa sta misurando lo studio?
Misure di risultato primarie
Misura del risultato |
Misura Descrizione |
Lasso di tempo |
|---|---|---|
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NPRS for pain
Lasso di tempo: upto 4 weeks
|
Pain intensity will be evaluated using the Numeric Pain Rating Scale, which ranges from 0 indicating "no pain" to 10 representing the "worst possible pain."
It has shown excellent test-retest reliability, with intraclass correlation coefficients (ICC) ranging between 0.95 and 0.98 in individuals with musculoskeletal conditions
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upto 4 weeks
|
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SLR and Slump test for neural mobility
Lasso di tempo: Upto 4 weeks
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To assess neural mobility, the Straight Leg Raise and Slump Tests will be employed.
These are well-established clinical tools for identifying lumbar nerve root irritation.
The SLR test demonstrates strong diagnostic accuracy (~81%) and excellent inter-rater reliability with kappa values above 0.90 and aprox 0.71 for slump test
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Upto 4 weeks
|
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Oswestry Disability Index test for functional outcome
Lasso di tempo: Upto 4 weeks
|
The ODI will be used to determine the level of functional disability associated with lower back pain.
It includes 10 items that assess various aspects of daily activity.
The tool has proven to be highly reliable (Cronbach's alpha = 0.87) and valid across different patient populations with lumbar spine conditions
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Upto 4 weeks
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Time up and go (TUG) test for functional outcome
Lasso di tempo: Upto 4 weeks
|
Balance and functional mobility will be measured using the TUG test, which involves timing a patient as they rise from a chair, walk three meters, turn, return, and sit down.
This test is highly reliable (ICC = 0.82 to 0.99) and shows good concurrent validity in both spinal and geriatric populations (34).
The cutoff value for balance and functional mobility TUG test is 7.2 sec
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Upto 4 weeks
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Five repetition sit to stand test
Lasso di tempo: upto 4 weeks
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The 5 Rep Sit-to-Stand Test will be used to assess lower limb strength and functional performance.
The patient gets to their maximum standing position and then sits back down five times as fast as they can without the use of their hands or arms.
It has demonstrated excellent reliability (ICC > 0.90) and shows strong correlation with functional ability (36).
The cutoff value is > 10 sec for 5 rep sitting to standing and standing to sitting transition
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upto 4 weeks
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Collaboratori e investigatori
Qui è dove troverai le persone e le organizzazioni coinvolte in questo studio.
Sponsor
Investigatori
- Investigatore principale: Amna Zia, PhD, King Edward Medical University
- Investigatore principale: Muniba Tahir, Riphah International University, Lahore Campus
Pubblicazioni e link utili
La persona responsabile dell'inserimento delle informazioni sullo studio fornisce volontariamente queste pubblicazioni. Questi possono riguardare qualsiasi cosa relativa allo studio.
Pubblicazioni generali
- George SZ, Fritz JM, Silfies SP, Schneider MJ, Beneciuk JM, Lentz TA, Gilliam JR, Hendren S, Norman KS. Interventions for the Management of Acute and Chronic Low Back Pain: Revision 2021. J Orthop Sports Phys Ther. 2021 Nov;51(11):CPG1-CPG60. doi: 10.2519/jospt.2021.0304.
- Senol D, Erdem C, Canbolat M, Toy S, Karatas T, Baykara RA, Ozbag D, Akyurek G. Comparison of the effects of conventional physiotherapy and proprioception exercises on pain and ankle proprioception in patients with lumbar radiculopathy. J Back Musculoskelet Rehabil. 2022;35(2):421-428. doi: 10.3233/BMR-200361.
- Ashraf B, Ahmad S, Ashraf K, Kanwal S, Ashraf S, Khan N, et al. Effectiveness of spinal mobilization with leg movement versus McKenzie back extension exercises in lumbar radiculopathy. 2021;15(5):1436-40.
- Fatima A, Mehmood Z, Ahmad SJJoIIMC. Effects of Mulligan Traction Straight Leg Raise Versus Passive Straight Leg Raise in Lumbar Radiculopathy Patients. 2022;17(2):86-90.
- Singh V, Malik MJRJoN. Lumbar radiculopathy managed with spinal mobilization with leg movement: A case study. 2021;20(2):246-9.
- Naidu SP, Srikantaiah S, Boyle RJIJoPT, Research. Immediate Effect of Mulligan's Spinal Mobilization with Limb Movements on Straight Leg Raise Test in Patients with Lumbar Radiculopathy: A Randomized Controlled Trial. 2023;5(1):66-72.
- Singh V, Malik MJAiR. Effect of manual therapy on pain, disability and neural mobility in patients of lumbar prolapsed intervertebral disc: a randomized controlled trial. 2022;36(3):11-8.
- Yasmeen S, Ahmad Z, Ishtiaq NJJRCoRS. The comparative effects of Butler's neural tissue mobilization and Mulligan's Bent leg raise in patients with chronic lumbar radiculopathy. 2022;10(02).
- Lin LH, Lin TY, Chang KV, Wu WT, Ozcakar L. Neural Mobilization for Reducing Pain and Disability in Patients with Lumbar Radiculopathy: A Systematic Review and Meta-Analysis. Life (Basel). 2023 Nov 26;13(12):2255. doi: 10.3390/life13122255.
- Hussein H, Atteya M, Ansari A, Kamel E. A Systematic Review and Meta-Analysis of the Effectiveness of Mulligan Mobilization with Movement on Pain, Range of Motion, Function, and Flexibility in Patients with Sciatica. NeuroRehabilitation. 2025 Mar;56(2):83-96. doi: 10.1177/10538135241301693. Epub 2024 Dec 18.
Studiare le date dei record
Queste date tengono traccia dell'avanzamento della registrazione dello studio e dell'invio dei risultati di sintesi a ClinicalTrials.gov. I record degli studi e i risultati riportati vengono esaminati dalla National Library of Medicine (NLM) per assicurarsi che soddisfino specifici standard di controllo della qualità prima di essere pubblicati sul sito Web pubblico.
Studia le date principali
Inizio studio (Effettivo)
20 giugno 2026
Completamento primario (Stimato)
20 agosto 2026
Completamento dello studio (Stimato)
20 settembre 2026
Date di iscrizione allo studio
Primo inviato
21 luglio 2026
Primo inviato che soddisfa i criteri di controllo qualità
21 luglio 2026
Primo Inserito (Effettivo)
24 luglio 2026
Aggiornamenti dei record di studio
Ultimo aggiornamento pubblicato (Effettivo)
24 luglio 2026
Ultimo aggiornamento inviato che soddisfa i criteri QC
21 luglio 2026
Ultimo verificato
1 luglio 2026
Maggiori informazioni
Termini relativi a questo studio
Parole chiave
Termini MeSH pertinenti aggiuntivi
Altri numeri di identificazione dello studio
- REC/RCR&AHS/25/0132 Muniba
Piano per i dati dei singoli partecipanti (IPD)
Hai intenzione di condividere i dati dei singoli partecipanti (IPD)?
NO
Informazioni su farmaci e dispositivi, documenti di studio
Studia un prodotto farmaceutico regolamentato dalla FDA degli Stati Uniti
No
Studia un dispositivo regolamentato dalla FDA degli Stati Uniti
No
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