Evidence and consensus based GKJR guidelines for the treatment of juvenile idiopathic arthritis
Gregor Dueckers, Nihal Guellac, Martin Arbogast, Guenther Dannecker, Ivan Foeldvari, Michael Frosch, Gerd Ganser, Arnd Heiligenhaus, Gerd Horneff, Arnold Illhardt, Ina Kopp, Ruediger Krauspe, Barbara Markus, Hartmut Michels, Matthias Schneider, Wolfram Singendonk, Helmut Sitter, Marianne Spamer, Norbert Wagner, Tim Niehues, Gregor Dueckers, Nihal Guellac, Martin Arbogast, Guenther Dannecker, Ivan Foeldvari, Michael Frosch, Gerd Ganser, Arnd Heiligenhaus, Gerd Horneff, Arnold Illhardt, Ina Kopp, Ruediger Krauspe, Barbara Markus, Hartmut Michels, Matthias Schneider, Wolfram Singendonk, Helmut Sitter, Marianne Spamer, Norbert Wagner, Tim Niehues
Abstract
Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children and adolescents. Immunomodulatory drugs are used frequently in its treatment. Using the nominal group technique (NGT) and Delphi method, we created a multidisciplinary, evidence- and consensus-based treatment guideline for JIA based on a systematic literature analysis and three consensus conferences. Conferences were headed by a professional moderator and were attended by representatives who had been nominated by their scientific societies or organizations. 15 statements regarding drug therapy, symptomatic and surgical management were generated. It is recommended that initially JIA is treated with NSAID followed by local glucocorticoids and/or methotrexate if unresponsive. Complementing literature evidence with long-standing experience of caregivers allows creating guidelines that may potentially improve the quality of care for children and adolescents with JIA.
Copyright © 2011 Elsevier Inc. All rights reserved.
Source: PubMed