Parental coronavirus disease vaccine hesitancy for children in Bangladesh: a cross-sectional study

Mohammad Ali, Sohel Ahmed, Atia Sharmin Bonna, Abu-Sufian Sarkar, Md Ariful Islam, Tania Akter Urmi, Tasnuva Samarukh Proma, Mohammad Ali, Sohel Ahmed, Atia Sharmin Bonna, Abu-Sufian Sarkar, Md Ariful Islam, Tania Akter Urmi, Tasnuva Samarukh Proma

Abstract

Background: Coronavirus disease 2019 (COVID-19) requires mass immunization to control the severity of symptoms and global spread. Data from developed countries have shown a high prevalence of parental COVID-19 vaccine hesitancy. However, parental vaccine hesitancy data in low- and middle-income countries are scarce. This study aimed to assess the prevalence of parental vaccine hesitancy and identify subgroups with higher odds of vaccine hesitancy in parents in Bangladesh. Methods: A cross-sectional study was conducted on the parents of children aged <18 years from October 10, 2021 to October 31, 2021. Parents participated in face-to-face interviews in randomly selected locations in Bangladesh using a vaccine hesitancy questionnaire. Factors associated with COVID-19 vaccine hesitancy were identified using binary logistic regression analysis. Results: Data from 2,633 eligible parents were analyzed. Overall, 42.8% reported COVID-19 vaccine hesitancy for their youngest child. The final model suggested the following factors were associated with hesitancy: children's age; parent's age, religion, occupation, monthly household income, permanent address, living location, status of tobacco use, adherence with regular government vaccination programs (other than COVID-19), perceptions of COVID-19 vaccine efficacy among Bangladeshi children, self-vaccination intentions, reported family members' illness or death from COVID-19, and perceived threat of COVID-19 were the independent predictors of parental COVID-19 vaccine hesitancy. Conversely, participants who were not tobacco users, parents who were very likely to believe that their children or family members could be infected with COVID-19 in the following year and who were very concerned about their children or a family member contracting COVID-19 in the next year had significantly lower odds of COVID-19 vaccine hesitancy. Conclusions: Our study suggested that vaccine hesitation varied based on sociodemographic characteristics, religion, behavior, and perceived COVID-19 threat. Therefore, interventions focused on addressing vaccine hesitancy among specific subgroups are warranted.

Keywords: Bangladesh; COVID-19; developing countries; parents; pediatrics; vaccine hesitancy..

Conflict of interest statement

No competing interests were disclosed.

Copyright: © 2022 Ali M et al.

Figures

Figure 1.
Figure 1.
Likelihood of COVID-19 vaccine acceptance/refusal by Bangladeshi parents for children aged

References

    1. Hodgson SH, Mansatta K, Mallett G, et al. : What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines against SARS-CoV-2. Lancet Infect. Dis. 2021 Feb 1 [cited 2022 Jan 13];21(2):e26–e35. 10.1016/S1473-3099(20)30773-8
    1. Randolph HE, Barreiro LB: Herd Immunity: Understanding COVID-19. Immunity. 2020 [cited 2021 Oct 28];52:737–741. Cell Press. 10.1016/j.immuni.2020.04.012
    1. Alfieri NL, Kusma JD, Heard-Garris N, et al. : Parental COVID-19 vaccine hesitancy for children: vulnerability in an urban hotspot. BMC Public Health. 2021 Dec 13 [cited 2021 Oct 28];21(1):1662. 10.1186/s12889-021-11725-5
    1. MacDonald NE: Vaccine hesitancy: Definition, scope and determinants. Vaccine. 2015 Aug 14 [cited 2021 Jan 16];33(34):4161–4164. 10.1016/j.vaccine.2015.04.036
    1. Cascini F, Pantovic A, Al-Ajlouni Y, et al. : Attitudes, acceptance and hesitancy among the general population worldwide to receive the COVID-19 vaccines and their contributing factors: A systematic review. iScience. 2021 Oct [cited 2021 Oct 29];40:101113. 10.1016/j.eclinm.2021.101113
    1. World Health Organization: Weekly Operational Update on COVID-19. World Heal Organ;2021; (February):1–10.
    1. Kostoff RN, Calina D, Kanduc D, et al. : Why are we vaccinating children against COVID-19?. Toxicol. Rep. 2021 Jan 1;8:1665–1684. 10.1016/j.toxrep.2021.08.010
    1. Bagateli LE, Saeki EY, Fadda M, et al. : COVID-19 Vaccine Hesitancy among Parents of Children and Adolescents Living in Brazil. Vaccine. 2021 Sep 30 [cited 2021 Oct 5];9(10):1115. 10.3390/vaccines9101115
    1. Zhang M-X, Lin X-Q, Chen Y, et al. : Determinants of parental hesitancy to vaccinate their children against COVID-19 in China. Expert Rev. Vaccines. 2021 Aug 23 [cited 2021 Oct 5];20:1339–1349. 10.1080/14760584.2021.1967147
    1. Ali M, Hossain A: What is the extent of COVID-19 vaccine hesitancy in Bangladesh? A cross-sectional rapid national survey. BMJ Open. 2021 Aug 24 [cited 2021 Aug 24];11(8):e050303. 10.1136/bmjopen-2021-050303
    1. Jamison AM, Quinn SC, Freimuth VS: “You don’t trust a government vaccine”: Narratives of institutional trust and influenza vaccination among African American and white adults. Soc. Sci. Med. 2019 Jan [cited 2021 Nov 4];221:87–94. 10.1016/j.socscimed.2018.12.020
    1. Kempe A, Saville AW, Albertin C, et al. : Parental Hesitancy About Routine Childhood and Influenza Vaccinations: A National Survey. Pediatrics. 2020 Jul 1 [cited 2021 Nov 4];146(1):e20193852. 10.1542/peds.2019-3852
    1. Hamel L, Lopes L, Kearney A, et al. : KFF COVID-19 vaccine monitor: Parents and the pandemic. KFF. 2021 [cited 2021 Nov 4].
    1. Faria NR, Mellan TA, Whittaker C, et al. : Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil. Science (80-). 2021 May 21 [cited 2021 Nov 4];372(6544):815–821. 10.1126/science.abh2644
    1. Mlcochova P, Kemp SA, Dhar MS, et al. : SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion. Nature. 2021 Nov 4 [cited 2021 Nov 4];599(7883):114–119. 10.1038/s41586-021-03944-y
    1. Mathieu Edouard RH: Coronavirus (COVID-19) Vaccinations - Statistics and Research - Our World in Data. Nat. Hum. Behav. 2021 [cited 2021 Nov 4];5–7.
    1. United Nations Population Fund: Handbook of Disease Burdens and Quality of Life Measures. New York, NY: Springer New York;2010 [cited 2021 Nov 7];4344–4344.
    1. Children 12 and above to get jabs|The Daily Star:[cited 2021 Nov 7].
    1. Taherdoost H: Determining sample size; How to calculate survey sample size. Int J Econ Manag Syst. 2017;2(2):237–239.
    1. James E, Joe W, Chadwick C: Organizational research: Determining appropriate sample size in survey research. Inf. Technol. Learn. Perform. J. 2001;19(1):43–50.
    1. Szilagyi PG, Shah MD, Delgado JR, et al. : Parents’ Intentions and Perceptions About COVID-19 Vaccination for Their Children: Results From a National Survey. Pediatrics. 2021 Oct;148(4):e2021052335. 10.1542/peds.2021-052335
    1. Aldakhil H, Albedah N, Alturaiki N, et al. : Vaccine hesitancy towards childhood immunizations as a predictor of mothers’ intention to vaccinate their children against COVID-19 in Saudi Arabia. J. Infect. Public Health. 2021 Oct 1 [cited 2021 Nov 6];14(10):1497–1504. 10.1016/j.jiph.2021.08.028
    1. Mohd Azizi FS, Kew Y, Moy FM: Vaccine hesitancy among parents in a multi-ethnic country, Malaysia. Vaccine. 2017 May 19 [cited 2021 Oct 6];35(22):2955–2961. 10.1016/j.vaccine.2017.04.010
    1. Caserotti M, Girardi P, Rubaltelli E, et al. : Associations of COVID-19 risk perception with vaccine hesitancy over time for Italian residents. Soc. Sci. Med. 2021 Mar 1 [cited 2021 Jun 17];272:113688. 10.1016/j.socscimed.2021.113688
    1. Kucukkarapinar M, Karadag F, Budakoglu I, et al. : COVID-19 Vaccine Hesitancy and Its Relationship With Illness Risk Perceptions, Affect, Worry, and Public Trust: An Online Serial Cross-Sectional Survey From Turkey. Psychiatry Clin Psychopharmacol. 2021 Apr 12;31(1):98–109. 10.5152/pcp.2021.21017
    1. Bertin P, Nera K, Delouvée S: Conspiracy Beliefs, Rejection of Vaccination, and Support for hydroxychloroquine: A Conceptual Replication-Extension in the COVID-19 Pandemic Context. Front. Psychol. 2020 Sep 18; 0:2471.
    1. Teasdale CA, Borrell LN, Shen Y, et al. : Parental plans to vaccinate children for COVID-19 in New York city. Vaccine. 2021 Aug;39(36):5082–5086. 10.1016/j.vaccine.2021.07.058
    1. Lazarus JV, Ratzan SC, Palayew A, et al. : A global survey of potential acceptance of a COVID-19 vaccine. Nat. Med. 2020 Oct 20 [cited 2021 Jan 16];27:225–228. 10.1038/s41591-020-1124-9
    1. Al-Mohaithef M, Padhi BK: Determinants of COVID-19 Vaccine Acceptance in Saudi Arabia: A Web-Based National Survey. J. Multidiscip. Healthc. 2020 Nov 20 [cited 2021 Feb 5];13:1657–1663. 10.2147/JMDH.S276771
    1. Malik AA, McFadden SM, Elharake J, et al. : Determinants of COVID-19 vaccine acceptance in the US. EClinicalMedicine. 2020 Sep [cited 2021 Jan 14];26:100495. 10.1016/j.eclinm.2020.100495
    1. Xiao X, Wong RM: Vaccine hesitancy and perceived behavioral control: A meta-analysis. Vaccine. 2020 Jul 14 [cited 2021 Feb 5];38(33):5131–5138. 10.1016/j.vaccine.2020.04.076
    1. Larson HJ, Jarrett C, Eckersberger E, et al. : Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature, 2007-2012. Vaccine. 2014;32:2150–2159. Elsevier BV. 10.1016/j.vaccine.2014.01.081
    1. Wilson K, Nguyen HH, Brehaut H: Acceptance of a pandemic influenza vaccine: a systematic review of surveys of the general public. Infect Drug Resist. 2011 Oct 20 [cited 2021 Feb 5];4(1):197. 10.2147/IDR.S23174
    1. Reno C, Maietti E, Di Valerio Z, et al. : Vaccine Hesitancy towards COVID-19 Vaccination: Investigating the Role of Information Sources through a Mediation Analysis. Infect Dis Rep. 2021 Aug 12 [cited 2021 Nov 7];13(3):712–723. 10.3390/idr13030066
    1. Ali M: Parental Coronavirus Disease Vaccine Hesitancy for Children in Bangladesh: A Cross-sectional Study. OSF. 2022 January 14. 10.17605/

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