Diagnosis and management of acute graft-versus-host disease

Fiona L Dignan, Andrew Clark, Persis Amrolia, Jacqueline Cornish, Graham Jackson, Prem Mahendra, Julia J Scarisbrick, Peter C Taylor, Nedim Hadzic, Bronwen E Shaw, Michael N Potter, Haemato-oncology Task Force of British Committee for Standards in Haematology, British Society for Blood and Marrow Transplantation, Fiona L Dignan, Andrew Clark, Persis Amrolia, Jacqueline Cornish, Graham Jackson, Prem Mahendra, Julia J Scarisbrick, Peter C Taylor, Nedim Hadzic, Bronwen E Shaw, Michael N Potter, Haemato-oncology Task Force of British Committee for Standards in Haematology, British Society for Blood and Marrow Transplantation

Abstract

A joint working group established by the Haemato-oncology subgroup of the British Committee for Standards in Haematology (BCSH) and the British Society for Bone Marrow Transplantation (BSBMT) has reviewed the available literature and made recommendations for the diagnosis and management of acute graft-versus-host disease. This guideline includes recommendations for the diagnosis and grading of acute graft-versus-host disease as well as primary treatment and options for patients with steroid-refractory disease. The goal of treatment should be effective control of graft-versus-host disease while minimizing risk of toxicity and relapse.

© 2012 Blackwell Publishing Ltd.

Source: PubMed

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