Pilot Randomized Controlled Trial of Feasibility, Acceptability, and Preliminary Efficacy of a Web-Based Physical Activity and Sedentary Time Intervention for Survivors of Physical Inactivity-Related Cancers

Erika Rees-Punia, Corinne R Leach, J Lee Westmaas, Lauren F Dempsey, Amelia M Roberts, Joe R Nocera, Alpa V Patel, Erika Rees-Punia, Corinne R Leach, J Lee Westmaas, Lauren F Dempsey, Amelia M Roberts, Joe R Nocera, Alpa V Patel

Abstract

Background: This pilot study explored the feasibility, acceptability, and usability of a web-based intervention for survivors of physical inactivity-related cancers through a two-arm, 12-week randomized controlled trial. Secondarily, this study tested the change in physical activity (PA) and sedentary time with intervention exposure.

Methods: Prior to randomization to the intervention (n = 45) or behavior "as usual" wait-listed control (n = 40) groups, participants completed baseline surveys and an accelerometer protocol. The intervention focused on increasing PA and decreasing sedentary time through social cognitive theory techniques. Follow-up acceptability/usability surveys (intervention group only) and accelerometers were sent after the intervention period. Information on intervention completion, adverse events, and user statistics were collected to determine feasibility. Median login time and mean acceptability/usability scores were calculated.

Results: Participants (mean age = 60 ± 7 years) included female (n = 80, 94%) and male survivors of breast (82%), colon (6%), endometrial (6%), bladder (4%), and kidney (2%) cancer. Seventy-eight (91.7%) participants returned partially or fully complete post-intervention data. There were no reported injuries or safety concerns. Intervention participants logged into the website for a total of 95 min (Q1, Q3 = 11, 204). System usability scores (72 ± 3) indicated above average usability of the website. Changes in time spent active and sedentary were not statistically significantly different between groups (p = 0.45), but within-group changes suggested intervention group participants spent more time active and less time sedentary after the intervention.

Conclusion: Results of this pilot study suggest its feasibility and acceptability for survivors of several inactivity-related cancers. Additional research to determine long-term efficacy is warranted. This low-cost online-only intervention has the potential to have a very broad reach.

Trial registration: Clinical Trials Number: NCT03983083. Date registered: June 12th, 2019.

Keywords: Behavioral intervention; Cancer survivors; EHealth; Physical activity; Sedentary time.

Conflict of interest statement

The authors declare no competing interests.

© 2021. International Society of Behavioral Medicine.

Figures

Fig. 1
Fig. 1
Flow of participants
Fig. 2
Fig. 2
Baseline and follow-up proportion of daily wear time (mean: 922 min/day) spent sedentary, in light intensity physical activity (LPA), and in moderate-to-vigorous intensity physical activity (MVPA) as measured by accelerometry. a Intervention group baseline. b Intervention group follow-up. c Control group baseline. d Control group follow-up

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