Management of perianal fistulas in Crohn's disease: an up-to-date review
Manuela Marzo, Carla Felice, Daniela Pugliese, Gianluca Andrisani, Giammarco Mocci, Alessandro Armuzzi, Luisa Guidi, Manuela Marzo, Carla Felice, Daniela Pugliese, Gianluca Andrisani, Giammarco Mocci, Alessandro Armuzzi, Luisa Guidi
Abstract
Perianal disease is one of the most disabling manifestations of Crohn's disease. A multidisciplinary approach of gastroenterologist, colorectal surgeon and radiologist is necessary for its management. A correct diagnosis, based on endoscopy, magnetic resonance imaging, endoanal ultrasound and examination under anesthesia, is crucial for perianal fistula treatment. Available medical and surgical therapies are discussed in this review, including new local treatment modalities that are under investigation.
Keywords: Crohn’s disease; Drug therapy; Perianal fistula; Surgery; Tumor necrosis factor alpha.
Source: PubMed