Comparison of Abdominal Visceral Adipose Tissue Area Measured by Computed Tomography with That Estimated by Bioelectrical Impedance Analysis Method in Korean Subjects

Dong-Hwa Lee, Kyeong Seon Park, Soyeon Ahn, Eu Jeong Ku, Kyong Yeun Jung, Yoon Ji Kim, Kyoung Min Kim, Jae Hoon Moon, Sung Hee Choi, Kyong Soo Park, Hak Chul Jang, Soo Lim, Dong-Hwa Lee, Kyeong Seon Park, Soyeon Ahn, Eu Jeong Ku, Kyong Yeun Jung, Yoon Ji Kim, Kyoung Min Kim, Jae Hoon Moon, Sung Hee Choi, Kyong Soo Park, Hak Chul Jang, Soo Lim

Abstract

We evaluated the concordance between visceral fat area (VFA) estimated by bioelectrical impedance analysis (BIA) or computed tomography (CT) in Korean subjects with a wide range in age and body mass index (BMI). In 1006 individuals (mean age 55.2 ± 11.8 (19-87) years, mean BMI 26.0 ± 3.5 (17-46) kg/m², 48.9% men), VFA quantified by CT was compared with VFA using multifrequency BIA machines within 15 days. Concordance rates were compared by age or BMI using correlation analysis, Bland-Altman plots, and intraclass correlation coefficient (ICC). Using BIA data, we established a regression formula to reflect CT-VFA. The mean VFAs by CT and BIA were 131.9 ± 57.3 cm² and 110.5 ± 33.9 cm², respectively (r = 0.605, p < 0.001). The mean difference was 21.4 ± 45.6 cm², tending to increase with BMI. In women with BMI <25 kg/m² or age <50 years, the VFAs by BIA were similar to those by CT (ICC = 0.496 in BMI <25 kg/m² and ICC = 0.638 in age <50 years). However, the difference was greater in men with BMI ≥25 kg/m² or age ≥50 years. Applying our formula, the difference between estimations decreased to 0.2 ± 38.2cm². VFA estimated by BIA correlated well with that by CT, but a more accurate formula is needed to match CT data, particularly in older men or subjects with a high BMI.

Keywords: Korean; bioelectrical impedance; computed tomography; visceral fat area.

Figures

Figure 1
Figure 1
Correlation between VFA measured by CT and VFA estimated by BIA (A) and Bland-Altman plot for comparing the two methods (B).
Figure 2
Figure 2
Differences in VFA between CT and BIA methods according to BMI (A) and subjects age (B).
Figure 3
Figure 3
Calibration plots of prediction model in men (A) and women (B).
Figure 3
Figure 3
Calibration plots of prediction model in men (A) and women (B).
Figure 4
Figure 4
Correlation between VFA measured by CT and VFA estimated by BIA (A) and Bland-Altman plot for comparison between two methods (B) in subjects who performed CT and BIA within seven days.

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