Open fenestration discectomy versus microscopic fenestration discectomy for lumbar disc herniation: a randomized controlled trial

Abstract

Background: Fenestration discectomy, for symptomatic lumbar disc herniation, is the most common surgical procedure in spine surgery. It can be done by open or microscopic procedures. This study compared the results of fenestration microdiscectomy with open fenestration discectomy in the treatment of symptomatic lumbar disc herniation as a relation to the functional outcome, leg pain, back pain, hospital stay, returns to daily activity, cost, recurrence, reoperation and type of surgery for recurrent disc herniation.

Methods: 60 patients age (29 - 50 years), with L4-L5 disc herniation, are divided randomly into group A- 30 patients underwent an open fenestration discectomy- and group B- 30 patients underwent fenestration microdiscectomy. All patients are assessed at 1 week, 3 months, 6 months, 12 months after surgery for Oswestry disability index and Visual analogue scale for back pain and leg pain and followed up for 4 years.

Results: In both groups, all patients have minimal disability by Oswestry Disability Index after surgery. There were significant differences between means of post-operative Visual Analogue Scale for back pain between these two groups after 1 week (3.7 in group A versus 2.2 in group B) (t = 13.28, P = < 0.001*) and after 3 months (1.73 in group A versus 0.43 in group B) (t = 10.54, P = < 0.001*). There were no significant differences between two groups regarding post-operative VAS for leg pain, recurrence (5 patients in group A versus 4 patients in group B) and reoperation rate (2 patients in each group). There were significant differences between means of length of hospital stay (2.10 in group A versus 1.06 in group B) (P < 0.001), time of returning to daily activities (7.33 in group A versus 4.03 in group B) (P < 0.001) and cost of surgery (1996.66 in group A versus 3003.3 in group B) (P < 0.001).

Conclusion: Use of microscope in fenestration discectomy for treatment of symptomatic lumbar disc herniation can achieve the same goals of open fenestration regarding nerve root decompression and relief of leg pain with advantage of less back pain, less hospital staying and early return to daily activities with disadvantage of more cost with the use of microscope. With 4 years follow up, there was no significant deference in rate of recurrence and reoperation with the use of microscope but we found that type of surgery for recurrent cases may be less invasive if microscope was used in primary surgery.

Trial registration: NCT, NCT04112485. Registered 30 September 2019 - Retrospectively registered, https://ichgcp.net/clinical-trials-registry/NCT04112485.

Keywords: Back pain; Leg pain; Lumbar disc herniation; Microdiscectomy; Open fenestration discectomy; Oswestry disability index; Visual analogue scale.

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1

The distribution of group A patients according to ODI pre-operatively and 1 week, 3 months, 6 months and 12 months postoperatively

Fig. 2

The distribution of group B patients according to ODI pre-operatively and 1 week, 3 months, 6 months and 12 months postoperatively

Fig. 3

The mean differences of post-operative VAS for back pain between study groups

Fig. 4

The mean differences of post-operative VAS for leg pain between study groups

Fig. 5

Association between study group and type of disability at time of the recurrence (P = 1.000)

Fig. 6

Association between study group and intervention at time of the recurrence (P = 0.365)