Targeted memory reactivation of face-name learning depends on ample and undisturbed slow-wave sleep

Abstract

Face memory, including the ability to recall a person's name, is of major importance in social contexts. Like many other memory functions, it may rely on sleep. We investigated whether targeted memory reactivation during sleep could improve associative and perceptual aspects of face memory. Participants studied 80 face-name pairs, and then a subset of spoken names with associated background music was presented unobtrusively during a daytime nap. This manipulation preferentially improved name recall and face recognition for those reactivated face-name pairs, as modulated by two factors related to sleep quality; memory benefits were positively correlated with the duration of stage N3 sleep (slow-wave sleep) and negatively correlated with measures of sleep disruption. We conclude that (a) reactivation of specific face-name memories during sleep can strengthen these associations and the constituent memories, and that (b) the effectiveness of this reactivation depends on uninterrupted N3 sleep.

Conflict of interest statement

The authors declare no competing interests.

© 2022. The Author(s).

Figures

Fig. 1. Experimental procedure overview.

Stages of the protocol are illustrated at the top (with mean beginning and ending times). Details of the learning and testing procedures are listed below.

Fig. 2. Correlations between N3 duration and cueing effect.

N3 duration was correlated with the cuing effect on Δrecall (a), and with the cuing effect on Δrecognition (b).

Fig. 3. Correlations between sleep disruption and cueing effect.

Sleep disruption after a cue was negatively correlated with the cuing effect on Δrecall (a). Greater post-cue EEG power in the high beta band (17.03-20.35 Hz) was associated with a smaller cuing effect (b).