Awareness regarding and vaccines acceptability of human papillomavirus among parents of middle school students in Zunyi, Southwest China

Yan Xie, Li-Yu Su, Feng Wang, Hai-Yan Tang, Qiu-Ge Yang, Yi Jun Liu, Yan Xie, Li-Yu Su, Feng Wang, Hai-Yan Tang, Qiu-Ge Yang, Yi Jun Liu

Abstract

The objective of this study was to investigate the parent cognition of information regarding the human papillomavirus (HPV) and their willingness toward HPV vaccination of their middle-school-aged children in Zunyi, Guizhou Province, China.The results provide a basis for improving the awareness concerning HPV-related information as a key vaccination strategy for implementing the HPV vaccine in the local context. Methods include the random cluster sampling method and questionnaires to survey parents. General descriptive and single-factor analyses were used to assess cognition to determine factors influencing vaccine willingness. Of 1,074 parents, 28.2% (302) and 38.0% (408) had heard of HPV and its vaccine before the survey, and when given HPV-related information, 73.9% (794) parents were willing to vaccinate their children. Reasons why parents did or did not want the vaccination were surveyed, with lack of sufficient knowledge about HPV and its vaccine being the primary reason to refuse vaccination. Concerns about safety, effectiveness, and perceiving low risk are the biggest obstacle in promoting vaccination. When the price is <1000, most parents (56.1%) are willing to vaccinate their children; thus, cost is also one of the concerns. Therefore, strategies for improving public awareness regarding the risk of cervical cancer and confidence in vaccination must be considered by policymakers.If the national authority confirms that the vaccine is safe and effective, the vaccine should be included in the national immunization program to increase publicity, address safety concerns, and allow for price regulation.

Keywords: Cervical cancer; China; HPV; cervical cancer vaccine; human papillomavirus; vaccination laws.

References

    1. Bosch FX, Lorincz A, Muoz N, Meijer CJLM, Shah KV.. The causal relation between human papillomavirus and cervical cancer. J Clin Pathol. 2002;55:244–65. doi:10.1136/jcp.55.4.244.
    1. Seto K, Marra F, Raymakers A, Marra CA.. The cost effectiveness of human papillomavirus vaccines: a systematic review. Drugs. 2012;72:715–43. doi:10.2165/11599470-000000000-00000.
    1. Choi HCW, Leung GM, Woo PPS, Jit M, Wu JT. Acceptability and uptake of female adolescent HPV vaccination in Hong Kong: a survey of mothers and adolescents. Vaccine. 2013;32:78–84. doi:10.1016/j.vaccine.2013.10.068.
    1. Zhao S, Zhao FH. Research progress of HPV therapeutic vaccine. Zhonghua Yu Fang Yi Xue Za Zhi. 2018;52:556–60.
    1. Huh WK, Joura EA, Giuliano AR, Iversen OE, De Andrade RP, Ault KA, Bartholomew D, Cestero RM, Fedrizzi EN, Hirschberg AL, et al. Final efficacy, immunogenicity, and safety analyses of a nine-valent human papillomavirus vaccine in women aged 16–26 years: a randomised, double-blind trial. Lancet. 2017;10108:2143–59. doi:10.1016/S0140-6736(17)31821-4.
    1. Luo Q. How to choose three kinds of cervical cancer vaccine. Fam Med. 2019;625:34–35.
    1. Green LI, Mathews CS, Waller J, Kitchener H, Rebolj M. Attendance at early recall and colposcopy in routine cervical screening with human papillomavirus testing. Int J Cancer. 2020;148:1850–57. doi:10.1002/ijc.33348.
    1. World Health Organization . Fr fact sheet: human papillomavirus (hpv) and cervical cancer. J Investig Med. 2002;49:124–33.
    1. Allen JD, Coronado GD, Williams RS, Glenn B, Escoffery C, Fernandez M, Tuff RA, Wilson KM, Mullen PD. A systematic review of measures used in studies of human papillomavirus (hpv) vaccine acceptability. Vaccine. 2010;28:4027–37. doi:10.1016/j.vaccine.2010.03.063.
    1. Han YF, Zhuang YN, Li Y, Fang Y. Analysis of mothers’ acceptance of HPV vaccination of adolescent girls in Xiamen.Zhonghua yu fang yi xue za zhi. Chinese J Preven Med. medicine.2018;52:38–42
    1. Boscolorizzo PPM, Holzinger D. From HPV-positive towards HPV—driven oropharyngeal squamous cell carcinomas. Cancer Treat Rev. 2016;42:24–29. doi:10.1016/j.ctrv.2015.10.009.
    1. Rahimi S, Akaev I, Brennan PA, Virgo A, Marani C, Gomez RS, Yeoh CC. A proposal for classification of oropharyngeal squamous cell carcinoma: morphology and status of hpv by immunohistochemistry and molecular biology. J Oral Pathol Med. 2020;49:1–7. doi:10.1111/jop.12956.
    1. Xu C, Xie Y, Ma Q, Xu Y, Li X, Hao R. Correlation analysis between high risk HPV infection and cervical intraepithelial neoplasia in patients with cervical diseases. Int Med Health Guide. 2018;24:544–47.
    1. World Health Organization . Human papillomavirus vaccines: wHOposition paper. Paper presented at October 2014; 2014. Oct; Geneva: World Health Organization.
    1. Tchounga BK, Jaquet A, Coffie PA, Horo A, Sauvaget C, Adoubi I, Guie P, Dabis F, Sasco AJ, Ekouevi DK. Cervical cancer prevention in reproductive health services: knowledge, attitudes and practices of midwives in Cote d’Ivoire, West Africa. BMC Health Serv Res. 2014;14:1–8. doi:10.1186/1472-6963-14-165.
    1. Grandahl M, Chun Paek S, Grisurapong S, Sherer P, Tydén T, Lundberg P. Parents’ knowledge, beliefs, and acceptance of the HPV vaccination in relation to their socio-demographics and religious beliefs: a cross-sectional study in Thailand. Plos One. 2018;13:e0193054. doi:10.1371/journal.pone.0193054.
    1. Jialu H, Hong YL, Yijia C, Yenuan C, Xianhong H. Survey on parents’ awareness of HPV and vaccine and their willingness to vaccinate in 9–14-year-old girls in Hangzhou. China Public Health. 2017;36:1478–81.
    1. Viens IJ, Henley JS, Watson M, Markowitz LE, Thomas CC, Thompson TD, Razzaghi H, Saraiya M. Human papillomavirus-as sociated cancers-United States, 2008–2012. MMWR Morb Mortal Wkly Rep. 2016;65:258–61. doi:10.15585/mmwr.mm6526a1.
    1. Jiawei X, Wang LY. Study on willingness and influencing factors of human papillomavirus vaccination among children’s mothers in Chongqing. China Vaccine Immun. 2019;29:299–302.
    1. Ganczak M, Owsianka B, Korzeń M. Factors that predict parental willingness to have their children vaccinated against hpv in a country with low hpv vaccination coverage. Int J Environ Res Public Health. 2018;15:645. doi:10.3390/ijerph15040645.
    1. Tesfaye ZT, Bhagavathula AS, Gebreyohannes EA, Tegegn HG. Knowledge and awareness of cervical cancer and human papillomavirus among female students in an ethiopian university: a cross-sectional study. Int J Environ Res Public Health. 2019;10:198.
    1. Deng JJ, ZhangJ , Wang J, Zhu YH,Liu N,Zhang YY,Wang Y, Luan L. Investigation on the cognition of prevention and control of cervical cancer in parents of primary and secondary schools in suzhou. J Public Health Prev Med. 2019;30:138–41
    1. Sopian MM, Shaaban J, Yusoff SSM, Mohamad WMZW. Knowledge, decision-making and acceptance of human papilloma virus vaccination among parents of primary school students in kota bharu, kelantan, malaysia. Asian Pac J Cancer Prev. 2018;19:1509–14.
    1. Santhanes D, Yong CP, Yap YY, Saw PS, Chaiyakunapruk N, Khan TM. Factors influencing intention to obtain the hpv vaccine in south east asian and western pacific regions: a systematic review and meta-analysis. Sci Rep. 2018;8:3640. doi:10.1038/s41598-018-21912-x.

Source: PubMed

Sponsor e collaboratori

Condizioni mediche

Interventi farmacologici

3
Sottoscrivi