High Dietary ω-6:ω-3 PUFA Ratio Is Positively Associated with Excessive Adiposity and Waist Circumference
Nathaly Torres-Castillo, Jorge Antonio Silva-Gómez, Wendy Campos-Perez, Elisa Barron-Cabrera, Ivan Hernandez-Cañaveral, Mary Garcia-Cazarin, Yolanda Marquez-Sandoval, Karina Gonzalez-Becerra, Carlos Barron-Gallardo, Erika Martinez-Lopez, Nathaly Torres-Castillo, Jorge Antonio Silva-Gómez, Wendy Campos-Perez, Elisa Barron-Cabrera, Ivan Hernandez-Cañaveral, Mary Garcia-Cazarin, Yolanda Marquez-Sandoval, Karina Gonzalez-Becerra, Carlos Barron-Gallardo, Erika Martinez-Lopez
Abstract
Objective: The aim of this study was to analyze dietary ω-6:ω-3 polyunsaturated fatty acid (PUFA) ratio and its association with adiposity and serum adiponectin levels in a Mexican population.
Methods: In this cross-sectional study, individuals with a BMI ≥ 18.5 kg/m2, were classified using four methods to measure adiposity. Parameters of body composition were measured by InBody 3.0. Diet intake was evaluated prospectively using a 3-day written food record. Serum high-molecular weight adiponectin isoform was measured using an ELISA assay. Biochemical and adiposity variables were analyzed by tertiles of dietary ω-6:ω-3 PUFA ratio.
Results: A total of 170 subjects were recruited with a mean age of 36.9 ± 11.8 years. The 73.5% of subjects were women. Subjects in the higher tertile of dietary ω-6:ω-3 PUFA ratio had more adiposity and higher levels of triglycerides, VLDL-c, glucose, insulin and HOMA-IR than those in the first tertile (p < 0.05). Adiponectin levels showed a trend according to dietary ω-6:ω-3 PUFA ratio (p = 0.06). A linear regression model showed that waist circumference, insulin, and HOMA-IR have positive associations with dietary ω-6:ω-3 PUFA ratio.
Conclusion: This study suggests that high dietary ω-6:ω-3 PUFA ratio is positively associated with excessive adiposity and worse metabolic profile.
Keywords: Adiponectin; Adiposity; Obesity; Omegas; Polyunsaturated fatty acids.
© 2018 The Author(s) Published by S. Karger GmbH, Freiburg.
Figures
Source: PubMed