Survival of direct composite restorations placed under general anesthesia in adult patients with intellectual and/or physical disabilities

Mona Shaghayegh Maes, Philipp Kanzow, Valentina Hrasky, Annette Wiegand, Mona Shaghayegh Maes, Philipp Kanzow, Valentina Hrasky, Annette Wiegand

Abstract

Objectives: This study aimed to assess the survival of direct composite restorations placed under general anesthesia in adult patients with intellectual and/or physical disabilities.

Materials and methods: Survival of composite restorations placed under general anesthesia in adult patients with intellectual and/or physical disabilities was retrospectively analyzed. Failure was defined as the need for replacement of at least one surface of the original restoration or extraction of the tooth. Individual-, tooth-, and restoration-related factors were obtained from dental records. Five-year mean annual failure rate (mAFR) and median survival time were calculated (Kaplan-Meier statistics). The effect of potential risk factors on failure was tested using univariate log-rank tests and multivariate Cox-regression analysis (α = 5%).

Results: A total of 728 restorations in 101 patients were included in the analysis. The survival after 5 years amounted to 67.7% (5-year mAFR: 7.5%) and median survival time to 7.9 years. Results of the multivariate Cox-regression analysis revealed physical disability (HR: 50.932, p = 0.001) and combined intellectual/physical disability (HR: 3.145, p = 0.016) compared with intellectual disability only, presence of a removable partial denture (HR: 3.013, p < 0.001), and restorations in incisors (HR: 2.281, p = 0.013) or molars (HR: 1.693, p = 0.017) compared with premolars to increase the risk for failure.

Conclusion: Composite restorations placed under general anesthesia in adult patients with intellectual and/or physical disabilities showed a reasonable longevity as 67.7% survived at least 5 years.

Clinical relevance: Survival of composite restorations depends on risk factors that need to be considered when planning restorative treatment in patients with intellectual and/or physical disabilities. NCT04407520.

Keywords: Composite; Disability; Kaplan-Meier statistics; Longevity; Restoration.

Conflict of interest statement

The authors declare that they have no conflict of interest.

© 2021. The Author(s).

Figures

Fig. 1
Fig. 1
Kaplan-Meier survival curve with 95% confidence interval (over 8 years) of placed restorations, number of restorations at risk, restorations with events and censored restorations as well as mean annual failure rate (mAFR) after 5 years, and median survival time (MST)
Fig. 2
Fig. 2
Kaplan-Meier survival graphs and respective 95% confidence intervals (over 8 years) of categorical variables being significant in multi-variate Cox regression analysis with shared frailty

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