Platelet Activation: The Mechanisms and Potential Biomarkers

Seong-Hoon Yun, Eun-Hye Sim, Ri-Young Goh, Joo-In Park, Jin-Yeong Han, Seong-Hoon Yun, Eun-Hye Sim, Ri-Young Goh, Joo-In Park, Jin-Yeong Han

Abstract

Beyond hemostasis and thrombosis, an increasing number of studies indicate that platelets play an integral role in intercellular communication, mediating inflammatory and immunomodulatory activities. Our knowledge about how platelets modulate inflammatory and immunity has greatly improved in recent years. In this review, we discuss recent advances in the pathways of platelet activation and potential application of platelet activation biomarkers to diagnosis and prediction of disease states.

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Source: PubMed

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