Fractional CO2 laser as an effective modality in treatment of striae alba in skin types III and IV

Farahnaz Fatemi Naein, Mehrnaz Soghrati, Farahnaz Fatemi Naein, Mehrnaz Soghrati

Abstract

Context: Rapid stretching of the skin over the weak connective tissue leads to development of striae distensae. Recently, researchers have shown special interest towards use of fractional photothermolysis in treatment of striae and several studies have shown its usefulness. Our aim was to assess the efficacy of Fractional CO2 laser in treatment of striae alba.

Materials and methods: A randomized clinical trial was carried out in female patients with striae alba. Ninety two striae were randomly selected and divided into two groups. Five sessions of laser resurfacing, were performed in Group 1, every 2-4 weeks. Group 2 was treated with 10% glycolic acid+0.05% tretinoin cream nightly during the study. Photographs were taken from the striae before and two weeks after the end of treatment. Mean surface area of striae compared between two groups. Patients' views regarding the degree of improvement were assessed via visual analogue scale (VAS).

Results: Forty six striae in Group 1 underwent laser resurfacing and 46 matched striae in Group 2, were treated with topical cream. Mean difference of striae surface area, was significantly decreased after treatment in Group 1 (-37.1±15.6 cm(2)) in comparison with Group 2(-7.9±9 cm(2)) (P value >0.001). Mean VAS was significantly higher in Group 1 (3.05±0.74) compared to Group 2 (0.63±0.66) (P value >0.001).

Conclusions: Fractional photothermolysis via Fractional CO2 laser seems to be an effective method for treatment of striae alba.

Keywords: Fractional photothermolysis; fractional CO2 laser; striae alba; striae distensae.

Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Striae distensae on the right flank of a representative patient. Show significant improvement at 12 weeks post-treatment: (a) at baseline; (b) after 5 sessions of fractional photothermolysis
Figure 2
Figure 2
Striae distensae on the left flank of the same patient. Show relative improvement at 12 weeks post-treatment: (a) at baseline; (b) after 3 month treatment with 10% glycolic acid+0.05% tretinoin cream

References

    1. McDaniel DH. Laser therapy of stretch marks. Dermatol Clin. 2002;20:67–76, viii.
    1. Cho S, Park ES, Lee DH, Li K, Chung JH. Clinical features and risk factors for striae distensae in Korean adolescents. J Eur Acad Dermatol Venereol. 2006;20:1108–13.
    1. Elsaie ML, Baumann LS, Elsaaiee LT. Striae distensae (stretch marks) and different modalities of therapy: An update. Dermatol Surg. 2009;35:563–73.
    1. Burrows NP, Lovell CR. Disorders of connective tissue. In: Burns T, Breathnach S, Cox N, Griffiths C, editors. Rook’s Textbook of Dermatology. 8th ed. Oxford: Wiley-Blackwell; 2010. p. 455.
    1. Hermanns JF, Piérard GE. High-resolution epiluminescence colorimetry of striae distensae. J Eur Acad Dermatol Venereol. 2006;20:282–7.
    1. Atwal GS, Manku LK, Griffiths CE, Polson DW. Striae gravidarum in primiparae. Br J Dermatol. 2006;155:965–9.
    1. Taavoni S, Soltanipour F, Haghani H, Ansarian H, Kheirkhah M. Effects of olive oil on striae gravidarum in the second trimester of pregnancy. Complement Ther Clin Pract. 2011;17:167–9.
    1. Alster TS, Tanzi EL, Lazarus M. The use of fractional laser photothermolysis for the treatment of atrophic scars. Dermatol Surg. 2007;33:295–9.
    1. Hasegawa T, Matsukura T, Mizuno Y, Suga Y, Ogawa H, Ikeda S. Clinical trial of a laser device called fractional photothermolysis system for acne scars. J Dermatol. 2006;33:623–7.
    1. Behroozan DS, Goldberg LH, Dai T, Geronemus RG, Friedman PM. Fractional photothermolysis for the treatment of surgical scars: A case report. J Cosmet Laser Ther. 2006;8:35–8.
    1. Shin JU, Roh MR, Rah DK, Ae NK, Suh H, Chung KY. The effect of succinylated atelocollagen and ablative fractional resurfacing laser on striae distensae. J Dermatolog Treat. 2011;22:113–21.
    1. Yang YJ, Lee GY. Treatment of Striae Distensae with Nonablative Fractional Laser versus Ablative CO(2) Fractional Laser: A Randomized Controlled Trial. Ann Dermatol. 2011;23:481–9.
    1. Kim BJ, Lee DH, Kim MN, Song KY, Cho WI, Lee CK, et al. Fractional photothermolysis for the treatment of striae distensae in Asian skin. Am J Clin Dermatol. 2008;9:33–7.
    1. Stotland M, Chapas AM, Brightman L, Sukal S, Hale E, Karen J, et al. The safety and efficacy of fractional photothermolysis for the correction of striae distensae. J Drugs Dermatol. 2008;7:857–61.
    1. Bak H, Kim BJ, Lee WJ, Bang JS, Lee SY, Choi JH, et al. Treatment of striae distensae with fractional photothermolysis. Dermatol Surg. 2009;35:1215–20.
    1. De Angelis F, Kolesnikova L, Renato F, Liguori G. Fractional nonablative 1540-nm laser treatment of striae distensae in Fitzpatrick skin types II to IV: Clinical and histological results. Aesthet Surg J. 2011;31:411–9.
    1. Alexiades-Armenaka M, Sarnoff D, Gotkin R, Sadick N. Multi-center clinical study and review of fractional ablative CO 2 laser resurfacing for the treatment of rhytides, photoaging, scars and striae. J Drugs Dermatol. 2011;10:352–62.
    1. Lee SE, Kim JH, Lee SJ, Lee JE, Kang JM, Kim YK, et al. Treatment of striae distensae using an ablative 10,600-nm carbon dioxide fractional laser: A retrospective review of 27 participants. Dermatol Surg. 2010;36:1683–90.
    1. Ash K, Lord J, Zukowski M, McDaniel DH. Comparison of topical therapy for striae alba (20% glycolic acid/0.05% tretinoin versus 20% glycolic acid/10% L-ascorbic acid) Dermatol Surg. 1998;24:849–56.
    1. Mazzarello V, Farace F, Ena P, Fenu G, Mulas P, Piu L, et al. A superficial texture analysis of 70% glycolic acid topical therapy and striae distensae. Plast Reconstr Surg. 2012;129:589e–90e.
    1. Walia S, Alster TS. Prolonged clinical and histologic effects from CO 2 laser resurfacing of atrophic acne scars. Dermatol Surg. 1999;25:926–30.
    1. Schick U, Elhabony R. Prospective comparative study of lumbar sequestrectomy and microdiscectomy. Minim Invasive Neurosurg. 2009;52:180–5.
    1. Gould D, Kelly D, Goldstone L, Gammon J. Examining the validity of pressure ulcer risk assessment scales: Developing and using illustrated patient simulations to collect the data. J Clin Nurs. 2001;10:697–706.
    1. Alexiades-Armenakas MR, Dover JS, Kenneth AA. Laser therapy. In: Bolognia JL, Jorizzo JL, Rapini RP, editors. Dermatology. 2nd ed. St. Louis (MO): Mosby Elsevier; 2008. p. 2113.
    1. Glaich AS, Goldberg LH, Friedman RH, Friedman PM. Fractional photothermolysis for the treatment of postinflammatory erythema resulting from acne vulgaris. Dermatol Surg. 2007;33:842–6.

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