Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study
Enrica Menditto, Elisio Costa, Luis Midão, Sinthia Bosnic-Anticevich, Ettore Novellino, Slawomir Bialek, Vitalis Briedis, Alpana Mair, Rojin Rajabian-Soderlund, Sylvie Arnavielhe, Anna Bedbrook, Wienczyslawa Czarlewski, Isabella Annesi-Maesano, Josep M Anto, Philippe Devillier, Govert De Vries, Thomas Keil, Aziz Sheikh, Valentina Orlando, Désirée Larenas-Linnemann, Lorenzo Cecchi, Giulia De Feo, M Illario, Cristiana Stellato, Joao Fonseca, Joao Malva, Mario Morais-Almeida, Ana Maria Pereira, Ana Maria Todo-Bom, Violeta Kvedariene, Arunas Valiulis, Karl Christian Bergmann, Ludger Klimek, Ralph Mösges, Oliver Pfaar, Torsten Zuberbier, Vicky Cardona, Joaquim Mullol, Nikos G Papadopoulos, Emmanuel P Prokopakis, Mike Bewick, Dermot Ryan, Regina E Roller-Wirnsberger, Peter Valentin Tomazic, Alvaro A Cruz, Piotr Kuna, Boleslaw Samolinski, Wytske J Fokkens, Sietze Reitsma, Isabelle Bosse, Jean-François Fontaine, Daniel Laune, Tari Haahtela, Sanna Toppila-Salmi, Claus Bachert, Peter W Hellings, Erik Melén, Magnus Wickman, Carsten Bindslev-Jensen, Esben Eller, Robyn E O'Hehir, Cemal Cingi, Bilun Gemicioğlu, Omer Kalayci, Juan Carlos Ivancevich, Jean Bousquet, MASK group, Enrica Menditto, Elisio Costa, Luis Midão, Sinthia Bosnic-Anticevich, Ettore Novellino, Slawomir Bialek, Vitalis Briedis, Alpana Mair, Rojin Rajabian-Soderlund, Sylvie Arnavielhe, Anna Bedbrook, Wienczyslawa Czarlewski, Isabella Annesi-Maesano, Josep M Anto, Philippe Devillier, Govert De Vries, Thomas Keil, Aziz Sheikh, Valentina Orlando, Désirée Larenas-Linnemann, Lorenzo Cecchi, Giulia De Feo, M Illario, Cristiana Stellato, Joao Fonseca, Joao Malva, Mario Morais-Almeida, Ana Maria Pereira, Ana Maria Todo-Bom, Violeta Kvedariene, Arunas Valiulis, Karl Christian Bergmann, Ludger Klimek, Ralph Mösges, Oliver Pfaar, Torsten Zuberbier, Vicky Cardona, Joaquim Mullol, Nikos G Papadopoulos, Emmanuel P Prokopakis, Mike Bewick, Dermot Ryan, Regina E Roller-Wirnsberger, Peter Valentin Tomazic, Alvaro A Cruz, Piotr Kuna, Boleslaw Samolinski, Wytske J Fokkens, Sietze Reitsma, Isabelle Bosse, Jean-François Fontaine, Daniel Laune, Tari Haahtela, Sanna Toppila-Salmi, Claus Bachert, Peter W Hellings, Erik Melén, Magnus Wickman, Carsten Bindslev-Jensen, Esben Eller, Robyn E O'Hehir, Cemal Cingi, Bilun Gemicioğlu, Omer Kalayci, Juan Carlos Ivancevich, Jean Bousquet, MASK group
Abstract
Background: Mobile technology may help to better understand the adherence to treatment. MASK-rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient-centred ICT system. A mobile phone app (the Allergy Diary) central to MASK is available in 22 countries.
Objectives: To assess the adherence to treatment in allergic rhinitis patients using the Allergy Diary App.
Methods: An observational cross-sectional study was carried out on all users who filled in the Allergy Diary from 1 January 2016 to 1 August 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (MPR) and the Proportion of days covered (PDC) approach.
Results: A total of 12 143 users were registered. A total of 6 949 users reported at least one VAS data recording. Among them, 1 887 users reported ≥7 VAS data. About 1 195 subjects were included in the analysis of adherence. One hundred and thirty-six (11.28%) users were adherent (MPR ≥70% and PDC ≤1.25), 51 (4.23%) were partly adherent (MPR ≥70% and PDC = 1.50) and 176 (14.60%) were switchers. On the other hand, 832 (69.05%) users were non-adherent to medications (MPR <70%). Of those, the largest group was non-adherent to medications and the time interval was increased in 442 (36.68%) users.
Conclusion and clinical relevance: Adherence to treatment is low. The relative efficacy of continuous vs on-demand treatment for allergic rhinitis symptoms is still a matter of debate. This study shows an approach for measuring retrospective adherence based on a mobile app. This also represents a novel approach for analysing medication-taking behaviour in a real-world setting.
Keywords: adherence; mHealth; mobile technology; observational study; rhinitis; treatment.
© 2019 John Wiley & Sons Ltd.
Source: PubMed