High Speed Circuit Training and Cognition
2020年5月15日 更新者：Joseph Signorile、University of Miami
The Impact of Circuit Resistance Training on Cognition and Estimated Maximal Oxygen Consumption in Older Adults.
The purpose of this research study is to see if a weight training program can make a positive change in participant fitness as measured by the ability to use oxygen and help the participant remember things.
調査の概要
詳細な説明
The purpose of this research study is to see if a weight training program can make a positive change in cardiac fitness, that is a person's ability to use oxygen; and, if the program can help a person's memory, as measured by some standard tests.
The researchers will also ask the participant to attend two sessions with researchers at the Bascom-Palmer Eye Institute so they can take pictures of the participants' eyes to see how training changes the number of blood vessels.
This can be used by doctors and other clinicians to evaluate improvements blood flow to the brain due to training.
研究の種類
介入
入学 (実際)
30
段階
- 適用できない
連絡先と場所
このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。
研究場所
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Florida
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Coral Gables、Florida、アメリカ、33147
- Laboratory of Neruomuscular Research and Active Aging
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Coral Gables、Florida、アメリカ、33146-2416
- Max Orovitz Laboratories
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参加基準
研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。
適格基準
就学可能な年齢
60年～85年 (大人、高齢者)
健康ボランティアの受け入れ
はい
受講資格のある性別
全て
説明
Inclusion Criteria:
- Men and women between 60 and 85 years of age (inclusive)
- Ability to provide informed consent
- No medical contraindication to participation in an exercise program including unstable or active untreated major medical illness (i.e., cardiovascular disease, neurological or neuromuscular diseases, stroke, cancer, etc.).
Exclusion Criteria:
- Existing muscle-skeletal injury
- Mini-mental score <18
- Enrolled in another exercise program
- Unstable or active major medical illness
- Answer "Yes" to any questions on the Elder PAR-Q
- Pregnancy
研究計画
このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：処理
- 割り当て：ランダム化
- 介入モデル：並列代入
- マスキング：ダブル
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
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実験的：High-Velocity Resistance Circuttraining (HVRCT)
The participants will perform three circuits of 11 exercises that target the upper and lower body.
Training will gradually increase over the first three weeks from 1 to 3 circuits.
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The program will include three circuits of 11 exercises that target the upper and lower body.
Training will gradually increase over the first three week from 1 to 3 circuits.
他の名前：
Lectures on health and fitness
他の名前：
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実験的：Educational Control (CON)
A supervised program will be provided to the participants that includes lectures on health and fitness.
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The program will include three circuits of 11 exercises that target the upper and lower body.
Training will gradually increase over the first three week from 1 to 3 circuits.
他の名前：
Lectures on health and fitness
他の名前：
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この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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Changes in Cognition due to training
時間枠：Baseline, Week 14
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The MoCA will be used to detect mild cognitive impairment in the participants.
The total possible score is 30 points; a score of 26 or above is considered normal.
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Baseline, Week 14
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Submaximal cycle ergometer test to measure aerobic capacity
時間枠：Baseline, Week 14
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The Young Men's Club of America (YMCA) cycle ergometer test will be used to compute aerobic capacity using heart rate(HR).
Predicted oxygen consumption will be computed using the HR of the last two consecutive workloads performed and the maximum workload.
A maximal oxygen consumption of 36 milliliters per kilogram body weight per minute and above is considered excellent for men, while 30 milliliters per kilogram body weight per minute is considered excellent for women.
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Baseline, Week 14
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Change in episodic memory
時間枠：Baseline, Week 14
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The National Institutes of Health (NIH) Toolbox: Picture Sequence Memory Test measures episodic memory.
Participants are asked to reproduce a sequence of pictures that is shown on the screen.
Participants are given credit for each adjacent pair of pictures they correctly place (i.e., if pictures in locations 7 and 8 are placed in that order and adjacent to each other anywhere, such as slots 1 and 2, one point is awarded), up to the maximum value for the sequence, which is one less than the sequence length or 17.
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Baseline, Week 14
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Change in attention and inhibitory control
時間枠：Baseline, Week 14
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The NIH Toolbox Flanker test measures attention and inhibitory control.
Participant focuses on a given stimulus while inhibiting attention to stimuli flanking it.
This computed score ranges from 0-10, but if the score is less than 4, it indicates that the participant did not score high enough in accuracy (80 percent correct or less) to receive a reaction time score.
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Baseline, Week 14
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Change in working memory
時間枠：Baseline, Week 14
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The NIH Toolbox List Sorting test measures working memory.
Participant recalls and sequences different visually and orally presented stimuli.
List Sorting is scored by summing the total number of items correctly recalled and sequenced on 1-List and 2-List, which can range from 0-26.
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Baseline, Week 14
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Change in speed of cognitive processing
時間枠：Baseline, Week 14
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The NIH Toolbox Pattern Comparison Processing Speed test measures speed of processing.
Participants discern whether two side-by-side pictures are the same or not, with 85 seconds to respond to as many items as possible.
Items are simple so as to purely measure processing speed.
The participant's raw score is the number of items answered correctly in 85 seconds of response time, with a range of 0-130.
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Baseline, Week 14
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Changes in the power muscles can produce
時間枠：Baseline, Week 14
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The participants will stand up and down 3 times with a thin string attached to the participant's belt.
A total of five attempts will be performed by each participant, and the highest power output will be selected for use in the analysis.
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Baseline, Week 14
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Change in retinal microvascular density as a marker of cortical changes
時間枠：Baseline, Week 14
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Retinal microvascular density will be assessed using the Retinal Function Imager (RFI) scan protocol and Optical Coherence Tomography Angiography (OCTA).
Pictures will be taken of the subject's retina as they look into a special self-contained camera system.
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Baseline, Week 14
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二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
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Changes in body fat-free mass
時間枠：Baseline, Week 14
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Fat-free mass will be measured using a Tanita BC-418 bioelectrical impedance scale.
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Baseline, Week 14
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Changes in body weight
時間枠：Baseline, Week 14
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Body weight will be measured on an electronic scale
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Baseline, Week 14
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協力者と研究者
ここでは、この調査に関係する人々や組織を見つけることができます。
スポンサー
研究記録日
これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。
主要日程の研究
研究開始 (実際)
2019年8月1日
一次修了 (実際)
2020年4月30日
研究の完了 (実際)
2020年4月30日
試験登録日
最初に提出
2019年7月10日
QC基準を満たした最初の提出物
2019年7月16日
最初の投稿 (実際)
2019年7月17日
学習記録の更新
投稿された最後の更新 (実際)
2020年5月18日
QC基準を満たした最後の更新が送信されました
2020年5月15日
最終確認日
2020年5月1日
詳しくは
本研究に関する用語
その他の研究ID番号
- 20190518
個々の参加者データ (IPD) の計画
個々の参加者データ (IPD) を共有する予定はありますか?
いいえ
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いいえ
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いいえ
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