High Speed Circuit Training and Cognition
15 de mayo de 2020 actualizado por: Joseph Signorile, University of Miami
The Impact of Circuit Resistance Training on Cognition and Estimated Maximal Oxygen Consumption in Older Adults.
The purpose of this research study is to see if a weight training program can make a positive change in participant fitness as measured by the ability to use oxygen and help the participant remember things.
Descripción general del estudio
Estado
Terminado
Condiciones
Intervención / Tratamiento
Descripción detallada
The purpose of this research study is to see if a weight training program can make a positive change in cardiac fitness, that is a person's ability to use oxygen; and, if the program can help a person's memory, as measured by some standard tests.
The researchers will also ask the participant to attend two sessions with researchers at the Bascom-Palmer Eye Institute so they can take pictures of the participants' eyes to see how training changes the number of blood vessels.
This can be used by doctors and other clinicians to evaluate improvements blood flow to the brain due to training.
Tipo de estudio
Intervencionista
Inscripción (Actual)
30
Fase
- No aplica
Contactos y Ubicaciones
Esta sección proporciona los datos de contacto de quienes realizan el estudio e información sobre dónde se lleva a cabo este estudio.
Ubicaciones de estudio
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Florida
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Coral Gables, Florida, Estados Unidos, 33147
- Laboratory of Neruomuscular Research and Active Aging
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Coral Gables, Florida, Estados Unidos, 33146-2416
- Max Orovitz Laboratories
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Criterios de participación
Los investigadores buscan personas que se ajusten a una determinada descripción, denominada criterio de elegibilidad. Algunos ejemplos de estos criterios son el estado de salud general de una persona o tratamientos previos.
Criterio de elegibilidad
Edades elegibles para estudiar
60 años a 85 años (Adulto, Adulto Mayor)
Acepta Voluntarios Saludables
Sí
Géneros elegibles para el estudio
Todos
Descripción
Inclusion Criteria:
- Men and women between 60 and 85 years of age (inclusive)
- Ability to provide informed consent
- No medical contraindication to participation in an exercise program including unstable or active untreated major medical illness (i.e., cardiovascular disease, neurological or neuromuscular diseases, stroke, cancer, etc.).
Exclusion Criteria:
- Existing muscle-skeletal injury
- Mini-mental score <18
- Enrolled in another exercise program
- Unstable or active major medical illness
- Answer "Yes" to any questions on the Elder PAR-Q
- Pregnancy
Plan de estudios
Esta sección proporciona detalles del plan de estudio, incluido cómo está diseñado el estudio y qué mide el estudio.
¿Cómo está diseñado el estudio?
Detalles de diseño
- Propósito principal: Tratamiento
- Asignación: Aleatorizado
- Modelo Intervencionista: Asignación paralela
- Enmascaramiento: Doble
Armas e Intervenciones
Grupo de participantes/brazo |
Intervención / Tratamiento |
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Experimental: High-Velocity Resistance Circuttraining (HVRCT)
The participants will perform three circuits of 11 exercises that target the upper and lower body.
Training will gradually increase over the first three weeks from 1 to 3 circuits.
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The program will include three circuits of 11 exercises that target the upper and lower body.
Training will gradually increase over the first three week from 1 to 3 circuits.
Otros nombres:
Lectures on health and fitness
Otros nombres:
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Experimental: Educational Control (CON)
A supervised program will be provided to the participants that includes lectures on health and fitness.
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The program will include three circuits of 11 exercises that target the upper and lower body.
Training will gradually increase over the first three week from 1 to 3 circuits.
Otros nombres:
Lectures on health and fitness
Otros nombres:
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¿Qué mide el estudio?
Medidas de resultado primarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
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Changes in Cognition due to training
Periodo de tiempo: Baseline, Week 14
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The MoCA will be used to detect mild cognitive impairment in the participants.
The total possible score is 30 points; a score of 26 or above is considered normal.
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Baseline, Week 14
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Submaximal cycle ergometer test to measure aerobic capacity
Periodo de tiempo: Baseline, Week 14
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The Young Men's Club of America (YMCA) cycle ergometer test will be used to compute aerobic capacity using heart rate(HR).
Predicted oxygen consumption will be computed using the HR of the last two consecutive workloads performed and the maximum workload.
A maximal oxygen consumption of 36 milliliters per kilogram body weight per minute and above is considered excellent for men, while 30 milliliters per kilogram body weight per minute is considered excellent for women.
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Baseline, Week 14
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Change in episodic memory
Periodo de tiempo: Baseline, Week 14
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The National Institutes of Health (NIH) Toolbox: Picture Sequence Memory Test measures episodic memory.
Participants are asked to reproduce a sequence of pictures that is shown on the screen.
Participants are given credit for each adjacent pair of pictures they correctly place (i.e., if pictures in locations 7 and 8 are placed in that order and adjacent to each other anywhere, such as slots 1 and 2, one point is awarded), up to the maximum value for the sequence, which is one less than the sequence length or 17.
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Baseline, Week 14
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Change in attention and inhibitory control
Periodo de tiempo: Baseline, Week 14
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The NIH Toolbox Flanker test measures attention and inhibitory control.
Participant focuses on a given stimulus while inhibiting attention to stimuli flanking it.
This computed score ranges from 0-10, but if the score is less than 4, it indicates that the participant did not score high enough in accuracy (80 percent correct or less) to receive a reaction time score.
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Baseline, Week 14
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Change in working memory
Periodo de tiempo: Baseline, Week 14
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The NIH Toolbox List Sorting test measures working memory.
Participant recalls and sequences different visually and orally presented stimuli.
List Sorting is scored by summing the total number of items correctly recalled and sequenced on 1-List and 2-List, which can range from 0-26.
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Baseline, Week 14
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Change in speed of cognitive processing
Periodo de tiempo: Baseline, Week 14
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The NIH Toolbox Pattern Comparison Processing Speed test measures speed of processing.
Participants discern whether two side-by-side pictures are the same or not, with 85 seconds to respond to as many items as possible.
Items are simple so as to purely measure processing speed.
The participant's raw score is the number of items answered correctly in 85 seconds of response time, with a range of 0-130.
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Baseline, Week 14
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Changes in the power muscles can produce
Periodo de tiempo: Baseline, Week 14
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The participants will stand up and down 3 times with a thin string attached to the participant's belt.
A total of five attempts will be performed by each participant, and the highest power output will be selected for use in the analysis.
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Baseline, Week 14
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Change in retinal microvascular density as a marker of cortical changes
Periodo de tiempo: Baseline, Week 14
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Retinal microvascular density will be assessed using the Retinal Function Imager (RFI) scan protocol and Optical Coherence Tomography Angiography (OCTA).
Pictures will be taken of the subject's retina as they look into a special self-contained camera system.
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Baseline, Week 14
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Medidas de resultado secundarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
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Changes in body fat-free mass
Periodo de tiempo: Baseline, Week 14
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Fat-free mass will be measured using a Tanita BC-418 bioelectrical impedance scale.
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Baseline, Week 14
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Changes in body weight
Periodo de tiempo: Baseline, Week 14
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Body weight will be measured on an electronic scale
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Baseline, Week 14
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Colaboradores e Investigadores
Aquí es donde encontrará personas y organizaciones involucradas en este estudio.
Patrocinador
Fechas de registro del estudio
Estas fechas rastrean el progreso del registro del estudio y los envíos de resultados resumidos a ClinicalTrials.gov. Los registros del estudio y los resultados informados son revisados por la Biblioteca Nacional de Medicina (NLM) para asegurarse de que cumplan con los estándares de control de calidad específicos antes de publicarlos en el sitio web público.
Fechas importantes del estudio
Inicio del estudio (Actual)
1 de agosto de 2019
Finalización primaria (Actual)
30 de abril de 2020
Finalización del estudio (Actual)
30 de abril de 2020
Fechas de registro del estudio
Enviado por primera vez
10 de julio de 2019
Primero enviado que cumplió con los criterios de control de calidad
16 de julio de 2019
Publicado por primera vez (Actual)
17 de julio de 2019
Actualizaciones de registros de estudio
Última actualización publicada (Actual)
18 de mayo de 2020
Última actualización enviada que cumplió con los criterios de control de calidad
15 de mayo de 2020
Última verificación
1 de mayo de 2020
Más información
Términos relacionados con este estudio
Palabras clave
Otros números de identificación del estudio
- 20190518
Plan de datos de participantes individuales (IPD)
¿Planea compartir datos de participantes individuales (IPD)?
NO
Información sobre medicamentos y dispositivos, documentos del estudio
Estudia un producto farmacéutico regulado por la FDA de EE. UU.
No
Estudia un producto de dispositivo regulado por la FDA de EE. UU.
No
Esta información se obtuvo directamente del sitio web clinicaltrials.gov sin cambios. Si tiene alguna solicitud para cambiar, eliminar o actualizar los detalles de su estudio, comuníquese con register@clinicaltrials.gov. Tan pronto como se implemente un cambio en clinicaltrials.gov, también se actualizará automáticamente en nuestro sitio web. .
Ensayos clínicos sobre High-speed circuit resistance training
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University of New HampshireAmerican Heart Association; California State University, San MarcosTerminadoModificación de la dieta | Ejercicio | Presión arterial | Promoción de la salud | Factor de riesgo cardiovascularEstados Unidos