- ICH GCP
- 미국 임상 시험 레지스트리
- 임상시험 NCT03033953
Effects of Native Whey or Milk Supplementation on Adaptations to 12 Weeks of Strength Training in Young and Elderly
Effects of Native Whey and Milk Supplementation on Changes in Muscle Mass and Strength After 12 Weeks of Strength Training in Young and Elderly
연구 개요
상세 설명
Increasing or maintaining muscle mass is of great importance for populations ranging from athletes to patients and elderly. Resistance exercise and protein ingestion are two of the most potent stimulators of muscle protein synthesis. Both the physical characteristic of proteins (e.g. different digestion rates of whey and casein) and the amino acid composition, affects the potential of a certain protein to stimulate muscle protein synthesis. Given its superior ability to rapidly increase blood leucine concentrations to high levels, whey is often considered the most potent protein source to stimulate muscle protein synthesis. Native whey protein is produced by filtration of unprocessed milk. Consequently, native whey has different characteristics than milk. Of special interest is the higher amounts of the highly anabolic amino acid leucine in native whey.
The higher levels of leucine can be of great interest for elderly individuals as some studies in elderly has shown an anabolic resistance to the effects of protein feeding and strength training. By increasing levels of leucine one might overcome this anabolic resistance in the elderly.
The aim of this double-blinded, randomized, partial cross-over study is to compare the changes in muscle hypertrophy and strength after a 11 (elderly) or 12 (young) week training intervention with daily supplementation of either 2x20g of native whey or milk proteins in young and elderly individuals. In order to explain potential differences between supplements an acute study investigating acute responses in blood amino acid concentrations and intracellular signalling is planned, in a subgroup of participants, before and after the training intervention.
The investigators hypothesize that native whey will induce greater muscle hypertrophy and strength gains than milk.
연구 유형
등록 (실제)
단계
- 해당 없음
연락처 및 위치
연구 장소
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-
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Oslo, 노르웨이, 0863
- Norwegian School of Sport Sciences
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참여기준
자격 기준
공부할 수 있는 나이
건강한 자원 봉사자를 받아들입니다
연구 대상 성별
설명
Inclusion Criteria:
- Healthy in the sense that they can conduct training and testing
- Able to understand Norwegian language written and oral
- Between 20 and 45, or above 70 years of age
Exclusion Criteria:
- Diseases or injuries contraindicating participation
- Use of dietary supplements (e.g. proteins, vitamins and creatine)
- Lactose intolerance
- Allergy to milk
- Allergy towards local anesthetics (xylocain)
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 기초 과학
- 할당: 무작위
- 중재 모델: 병렬 할당
- 마스킹: 네 배로
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
|---|---|
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위약 비교기: Milk supplementation
11 (elderly) or 12 (young) weeks of strength training and daily supplementation of 2x20g milk protein.
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실험적: Native whey
11 (elderly) or 12 (young) weeks of strength training and daily supplementation of 2x20g native whey protein.
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연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
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Lean mass
기간: Before the training intervention
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Measured by whole body dual x-ray absorptiometry (DXA)
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Before the training intervention
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Lean mass
기간: After 11-12 weeks of strength training
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Measured by whole body dual x-ray absorptiometry (DXA)
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After 11-12 weeks of strength training
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2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
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Thigh muscle cross sectional area
기간: Before the training intervention
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Measured by magnetic resonance imaging (MRI)
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Before the training intervention
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Thigh muscle cross sectional area
기간: After 11-12 weeks of strength training
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Measured by magnetic resonance imaging (MRI)
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After 11-12 weeks of strength training
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Pectoralis muscle cross sectional area
기간: Before the training intervention
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Measured by magnetic resonance imaging (MRI)
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Before the training intervention
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Pectoralis muscle cross sectional area
기간: After 11-12 weeks of strength training
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Measured by magnetic resonance imaging (MRI)
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After 11-12 weeks of strength training
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Arm cross sectional area
기간: Before the training intervention
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Measured by magnetic resonance imaging (MRI)
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Before the training intervention
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Arm cross sectional area
기간: After 11-12 weeks of strength training
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Measured by magnetic resonance imaging (MRI)
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After 11-12 weeks of strength training
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Thickness of the lateral vasti
기간: Before the training intervention
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Measured by ultrasound
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Before the training intervention
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Thickness of the lateral vasti
기간: After 11-12 weeks of strength training
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Measured by ultrasound
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After 11-12 weeks of strength training
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1 repetition maximum in leg press
기간: Before the training intervention
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Before the training intervention
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1 repetition maximum in leg press
기간: After 11-12 weeks of strength training
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After 11-12 weeks of strength training
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1 repetition maximum in bench press
기간: Before the training intervention
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Before the training intervention
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1 repetition maximum in bench press
기간: After 11-12 weeks of strength training
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After 11-12 weeks of strength training
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Ratio of phosphorylated to total ribosomal protein S6 kinase beta-1(P70S6K) change from baseline
기간: 30 min before and 2 hours after exercise and protein supplement intake, before the training intervention
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Biopsies from m. Vastus Lateralis was analyzed by western blot
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30 min before and 2 hours after exercise and protein supplement intake, before the training intervention
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Ratio of phosphorylated to total ribosomal protein S6 kinase beta-1(P70S6K) change from baseline
기간: 30 min before and 2 hours after exercise and protein supplement intake, after 11-12 weeks of strength training
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Biopsies from m. Vastus Lateralis was analyzed by western blot
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30 min before and 2 hours after exercise and protein supplement intake, after 11-12 weeks of strength training
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Phosphorylation of phosphorylated to total eukaryotic elongation factor 2 (eEF-2) change from baseline
기간: 30 min before and 2 hours after exercise and protein supplement intake, before the training intervention
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Biopsies from m. Vastus Lateralis was analyzed by western blot
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30 min before and 2 hours after exercise and protein supplement intake, before the training intervention
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Phosphorylation of phosphorylated to total eukaryotic elongation factor 2 (eEF-2) change from baseline
기간: 30 min before and 2 hours after exercise and protein supplement intake, after 11-12 weeks of strength training
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Biopsies from m. Vastus Lateralis was analyzed by western blot
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30 min before and 2 hours after exercise and protein supplement intake, after 11-12 weeks of strength training
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Phosphorylation of phosphorylated to total eukaryotic translation initiation factor 4E-binding protein 1 (4EBP-1) change from baseline
기간: 30 min before and 2 hours after exercise and protein supplement intake, before the training intervention
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Biopsies from m. Vastus Lateralis was analyzed by western blot
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30 min before and 2 hours after exercise and protein supplement intake, before the training intervention
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Phosphorylation of phosphorylated to total eukaryotic translation initiation factor 4E-binding protein 1 (4EBP-1) change from baseline
기간: 30 min before and 2 hours after exercise and protein supplement intake, after 11-12 weeks of strength training
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Biopsies from m. Vastus Lateralis was analyzed by western blot
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30 min before and 2 hours after exercise and protein supplement intake, after 11-12 weeks of strength training
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Plasma amino acid concentration
기간: 60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, before the training intervention
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60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, before the training intervention
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Plasma amino acid concentration
기간: 60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, after 11-12 weeks of strength training
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60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, after 11-12 weeks of strength training
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Muscle force generating capacity change from baseline
기간: 15 min before, 10 min, 2.5 hours and 24 hours after exercise and protein supplement intake, before the training intervention
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Measured as unilateral isometric knee extension force (Nm) with 90° in the hip and knee joints.
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15 min before, 10 min, 2.5 hours and 24 hours after exercise and protein supplement intake, before the training intervention
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Muscle force generating capacity change from baseline
기간: 15 min before, 10 min, 2.5 hours and 24 hours after exercise and protein supplement intake, after 11-12 weeks of strength training
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Measured as unilateral isometric knee extension force (Nm) with 90° in the hip and knee joints.
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15 min before, 10 min, 2.5 hours and 24 hours after exercise and protein supplement intake, after 11-12 weeks of strength training
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Serum glucose
기간: 60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, before the training intervention
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60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, before the training intervention
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Serum glucose
기간: 60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, after 11-12 weeks of strength training
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60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, after 11-12 weeks of strength training
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Serum insulin
기간: 60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, before the training intervention
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60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, before the training intervention
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Serum insulin
기간: 60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, after 11-12 weeks of strength training
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60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, after 11-12 weeks of strength training
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Serum urea
기간: 60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, before the training intervention
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60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, before the training intervention
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Serum urea
기간: 60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, after 11-12 weeks of strength training
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60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, after 11-12 weeks of strength training
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Serum creatine kinase
기간: 60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, before the training intervention
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60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, before the training intervention
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Serum creatine kinase
기간: 60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, after 11-12 weeks of strength training
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60 min before and 45, 60, 75 and 120 min after exercise and protein supplement intake, after 11-12 weeks of strength training
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Tumor necrosis factor alfa messenger ribonucleic acid (mRNA)
기간: 30 min before exercise and protein intake, before training intervention
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30 min before exercise and protein intake, before training intervention
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Tumor necrosis factor alfa mRNA
기간: 2 hours after exercise and protein intake, before training intervention
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2 hours after exercise and protein intake, before training intervention
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Tumor necrosis factor alfa mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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Tumor necrosis factor alfa mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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Interleukin 6 mRNA
기간: 30 min before exercise and protein intake, before training intervention
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30 min before exercise and protein intake, before training intervention
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Interleukin 6 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
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2 hours after exercise and protein intake, before training intervention
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Interleukin 6 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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Interleukin 6 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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Interleukin 8 mRNA
기간: 30 min before exercise and protein intake, before training intervention
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30 min before exercise and protein intake, before training intervention
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Interleukin 8 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
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2 hours after exercise and protein intake, before training intervention
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Interleukin 8 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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Interleukin 8 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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Nuclear Receptor Subfamily 4 Group A Member 2 mRNA
기간: 30 min before exercise and protein intake, before training intervention
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30 min before exercise and protein intake, before training intervention
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Nuclear Receptor Subfamily 4 Group A Member 2 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
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2 hours after exercise and protein intake, before training intervention
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Nuclear Receptor Subfamily 4 Group A Member 2 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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Nuclear Receptor Subfamily 4 Group A Member 2 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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Interleukin 1b mRNA
기간: 30 min before exercise and protein intake, before training intervention
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30 min before exercise and protein intake, before training intervention
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Interleukin 1b mRNA
기간: 2 hours after exercise and protein intake, before training intervention
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2 hours after exercise and protein intake, before training intervention
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Interleukin 1b mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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Interleukin 1b mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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Interleukin 1 Receptor Antagonist mRNA
기간: 30 min before exercise and protein intake, before training intervention
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30 min before exercise and protein intake, before training intervention
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Interleukin 1 Receptor Antagonist mRNA
기간: 2 hours after exercise and protein intake, before training intervention
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2 hours after exercise and protein intake, before training intervention
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Interleukin 1 Receptor Antagonist mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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Interleukin 1 Receptor Antagonist mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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C-C Motif Chemokine Ligand 2 mRNA
기간: 30 min before exercise and protein intake, before training intervention
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30 min before exercise and protein intake, before training intervention
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C-C Motif Chemokine Ligand 2 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
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2 hours after exercise and protein intake, before training intervention
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C-C Motif Chemokine Ligand 2 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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C-C Motif Chemokine Ligand 2 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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Interleukin 4 mRNA
기간: 30 min before exercise and protein intake, before training intervention
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30 min before exercise and protein intake, before training intervention
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Interleukin 4 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
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2 hours after exercise and protein intake, before training intervention
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Interleukin 4 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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Interleukin 4 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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Interleukin 10 mRNA
기간: 30 min before exercise and protein intake, before training intervention
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30 min before exercise and protein intake, before training intervention
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Interleukin 10 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
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2 hours after exercise and protein intake, before training intervention
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Interleukin 10 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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Interleukin 10 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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C-X-C Motif Chemokine Ligand mRNA
기간: 30 min before exercise and protein intake, before training intervention
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30 min before exercise and protein intake, before training intervention
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C-X-C Motif Chemokine Ligand mRNA
기간: 2 hours after exercise and protein intake, before training intervention
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2 hours after exercise and protein intake, before training intervention
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C-X-C Motif Chemokine Ligand mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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C-X-C Motif Chemokine Ligand mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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Cholesterol 25-Hydroxylase mRNA
기간: 30 min before exercise and protein intake, before training intervention
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30 min before exercise and protein intake, before training intervention
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Cholesterol 25-Hydroxylase mRNA
기간: 2 hours after exercise and protein intake, before training intervention
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2 hours after exercise and protein intake, before training intervention
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Cholesterol 25-Hydroxylase mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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Cholesterol 25-Hydroxylase mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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C-C Motif Chemokine Ligand 8 mRNA
기간: 30 min before exercise and protein intake, before training intervention
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30 min before exercise and protein intake, before training intervention
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C-C Motif Chemokine Ligand 8 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
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2 hours after exercise and protein intake, before training intervention
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C-C Motif Chemokine Ligand 8 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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C-C Motif Chemokine Ligand 8 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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Interleukin 17D mRNA
기간: 30 min before exercise and protein intake, before training intervention
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30 min before exercise and protein intake, before training intervention
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Interleukin 17D mRNA
기간: 2 hours after exercise and protein intake, before training intervention
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2 hours after exercise and protein intake, before training intervention
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Interleukin 17D mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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Interleukin 17D mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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C-C Motif Chemokine Ligand 3 mRNA
기간: 30 min before exercise and protein intake, before training intervention
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30 min before exercise and protein intake, before training intervention
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C-C Motif Chemokine Ligand 3 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
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2 hours after exercise and protein intake, before training intervention
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C-C Motif Chemokine Ligand 3 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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C-C Motif Chemokine Ligand 3 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 Alpha mRNA
기간: 30 min before exercise and protein intake, before training intervention
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30 min before exercise and protein intake, before training intervention
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Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 Alpha mRNA
기간: 2 hours after exercise and protein intake, before training intervention
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2 hours after exercise and protein intake, before training intervention
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Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 Alpha mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 Alpha mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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C-X-C Motif Chemokine Ligand 16 mRNA
기간: 30 min before exercise and protein intake, before training intervention
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30 min before exercise and protein intake, before training intervention
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C-X-C Motif Chemokine Ligand 16 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
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2 hours after exercise and protein intake, before training intervention
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C-X-C Motif Chemokine Ligand 16 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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C-X-C Motif Chemokine Ligand 16 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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C-C Motif Chemokine Ligand 5 mRNA
기간: 30 min before exercise and protein intake, before training intervention
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30 min before exercise and protein intake, before training intervention
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C-C Motif Chemokine Ligand 5 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
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2 hours after exercise and protein intake, before training intervention
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C-C Motif Chemokine Ligand 5 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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C-C Motif Chemokine Ligand 5 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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Nuclear Receptor Subfamily 4 Group A Member 3 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
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Nuclear Receptor Subfamily 4 Group A Member 3 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
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Nuclear Receptor Subfamily 4 Group A Member 3 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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Nuclear Receptor Subfamily 4 Group A Member 3 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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Uncoupling Protein 1 mRNA
기간: 30 min before exercise and protein intake, before training intervention
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30 min before exercise and protein intake, before training intervention
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Uncoupling Protein 1 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
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Uncoupling Protein 1 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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Uncoupling Protein 1 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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Matrix Metallopeptidase 9 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
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Matrix Metallopeptidase 9 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
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Matrix Metallopeptidase 9 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
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30 min before exercise and protein intake, after 11-12 weeks of strength training
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Matrix Metallopeptidase 9 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
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2 hours after exercise and protein intake, after 11-12 weeks of strength training
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|
ATP Binding Cassette Subfamily A Member 1 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
ATP Binding Cassette Subfamily A Member 1 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
ATP Binding Cassette Subfamily A Member 1 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
ATP Binding Cassette Subfamily A Member 1 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Leukocyte Differentiation Antigen CD36 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Leukocyte Differentiation Antigen CD36 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Leukocyte Differentiation Antigen CD36 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Leukocyte Differentiation Antigen CD36 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Toll Like Receptor 2 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Toll Like Receptor 2 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Toll Like Receptor 2 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Toll Like Receptor 2 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Nuclear Receptor Subfamily 1 Group H Member 3 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Nuclear Receptor Subfamily 1 Group H Member 3 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Nuclear Receptor Subfamily 1 Group H Member 3 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Nuclear Receptor Subfamily 1 Group H Member 3 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Solute Carrier Family 3 Member 2 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Solute Carrier Family 3 Member 2 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Solute Carrier Family 3 Member 2 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Solute Carrier Family 3 Member 2 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Solute Carrier Family 7 Member 5 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Solute Carrier Family 7 Member 5 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Solute Carrier Family 7 Member 5 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Solute Carrier Family 7 Member 5 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Solute Carrier Family 36 Member 1 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Solute Carrier Family 36 Member 1 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Solute Carrier Family 36 Member 1 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Solute Carrier Family 36 Member 1 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Solute Carrier Family 38 Member 2 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Solute Carrier Family 38 Member 2 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Solute Carrier Family 38 Member 2 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Solute Carrier Family 38 Member 2 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Muscle-Specific RING Finger Protein 1 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Muscle-Specific RING Finger Protein 1 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Muscle-Specific RING Finger Protein 1 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Muscle-Specific RING Finger Protein 1 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Atrogin-1 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Atrogin-1 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Atrogin-1 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Atrogin-1 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Forkhead Box Protein O1A mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Forkhead Box Protein O1A mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Forkhead Box Protein O1A mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Forkhead Box Protein O1A mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Forkhead Box O3 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Forkhead Box O3 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Forkhead Box O3 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Forkhead Box O3 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Myosin Heavy Chain 7 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Myosin Heavy Chain 7 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Myosin Heavy Chain 7 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Myosin Heavy Chain 7 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Myosin Heavy Chain 2 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Myosin Heavy Chain 2 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Myosin Heavy Chain 2 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Myosin Heavy Chain 2 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Myosin Heavy Chain 1 mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Myosin Heavy Chain 1 mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Myosin Heavy Chain 1mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Myosin Heavy Chain 1 mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Insulin Like Growth Factor 1 mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Insulin Like Growth Factor 1 mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Insulin Like Growth Factor 1 mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Insulin Like Growth Factor 1 mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Mast Cell Growth Factor mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Mast Cell Growth Factor mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Mast Cell Growth Factor mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Mast Cell Growth Factor mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Hepatocyte Growth Factor mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Hepatocyte Growth Factor mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Hepatocyte Growth Factor mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Hepatocyte Growth Factor mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Myostatin mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Myostatin mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Myostatin mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Myostatin mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Striated Muscle Activator Of Rho-Dependent Signaling mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Striated Muscle Activator Of Rho-Dependent Signaling mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Striated Muscle Activator Of Rho-Dependent Signaling mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Striated Muscle Activator Of Rho-Dependent Signaling mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
JunB Proto-Oncogene, AP-1 Transcription Factor Subunit mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
JunB Proto-Oncogene, AP-1 Transcription Factor Subunit mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
JunB Proto-Oncogene, AP-1 Transcription Factor Subunit mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
JunB Proto-Oncogene, AP-1 Transcription Factor Subunit mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Actin, Alpha 1, Skeletal Muscle mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Actin, Alpha 1, Skeletal Muscle mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Actin, Alpha 1, Skeletal Muscle mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Actin, Alpha 1, Skeletal Muscle mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Colony Stimulating Factor 3 mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Colony Stimulating Factor 3 mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Colony Stimulating Factor 3 mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Colony Stimulating Factor 3 mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Prostaglandin-Endoperoxide Synthase 2 mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Prostaglandin-Endoperoxide Synthase 2 mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Prostaglandin-Endoperoxide Synthase 2 mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Prostaglandin-Endoperoxide Synthase 2 mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
TATA-Box Binding Protein mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
TATA-Box Binding Protein mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
TATA-Box Binding Protein mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
TATA-Box Binding Protein mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Filamin B mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Filamin B mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Filamin B mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Filamin B mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
2 hours after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Beta-2-Microglobulin mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, before training intervention
|
30 min before exercise and protein intake, before training intervention
|
|
|
Beta-2-Microglobulin mRNA Myosin Heavy Chain 1 mRNA
기간: 2 hours after exercise and protein intake, before training intervention
|
2 hours after exercise and protein intake, before training intervention
|
|
|
Beta-2-Microglobulin mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min before exercise and protein intake, after 11-12 weeks of strength training
|
30 min before exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Beta-2-Microglobulin mRNA Myosin Heavy Chain 1 mRNA
기간: 30 min after exercise and protein intake, after 11-12 weeks of strength training
|
30 min after exercise and protein intake, after 11-12 weeks of strength training
|
|
|
Fasting cholesterol (only in elderly)
기간: Before training intervention
|
Before training intervention
|
|
|
Fasting cholesterol (only in elderly)
기간: After 11-12 weeks of strength training
|
After 11-12 weeks of strength training
|
|
|
Fasting triglycerides (only in elderly)
기간: Before training intervention
|
Before training intervention
|
|
|
Fasting triglycerides (only in elderly)
기간: After 11-12 weeks of strength training
|
After 11-12 weeks of strength training
|
|
|
Fasting LDL (only in elderly)
기간: Before training intervention
|
Before training intervention
|
|
|
Fasting LDL (only in elderly)
기간: After 11-12 weeks of strength training
|
After 11-12 weeks of strength training
|
|
|
Fasting HDL (only in elderly)
기간: Before training intervention
|
Before training intervention
|
|
|
Fasting HDL (only in elderly)
기간: After 11-12 weeks of strength training
|
After 11-12 weeks of strength training
|
공동 작업자 및 조사자
연구 기록 날짜
연구 주요 날짜
연구 시작
기본 완료 (실제)
연구 완료 (실제)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (추정)
연구 기록 업데이트
마지막 업데이트 게시됨 (추정)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
이 연구와 관련된 용어
기타 연구 ID 번호
- Tine 12wk
개별 참가자 데이터(IPD) 계획
개별 참가자 데이터(IPD)를 공유할 계획입니까?
이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .
체력 단련에 대한 임상 시험
-
King's College LondonUniversity College, London; Brighton & Sussex Medical School완전한
-
MMSx Authority Institute for Movement Mechanics...완전한
-
VA Office of Research and Development아직 모집하지 않음