- ICH GCP
- 미국 임상 시험 레지스트리
- 임상시험 NCT07618208
Student Precarity and Psychiatry (PEPSY)
Impact of Precarity on the Emergence of Psychiatric Disorders and the Use of Care Among Students
Since the COVID-19 pandemic, mental health disorders have increased significantly, particularly among young people. In France, the proportion of young people aged 18 to 25 suffering from depression almost doubled between 2017 and 2021. This phenomenon particularly affects students, who are already identified as being at greater risk of mental health disorders than the general population. Medical students seem to be particularly vulnerable: in 2021, a national study showed very high rates of depression and suicidal thoughts in this population. The main factor associated with depression was the feeling of financial hardship.
Students often face multiple forms of insecurity. Financially, they have limited resources and struggle to cover their basic needs such as housing, food and healthcare. Socially, many experience significant isolation, particularly when they are away from their families or under pressure from their studies. All of this has a significant impact on their mental health. Unfortunately, many students do not seek help due to lack of time, resources, or awareness of support services. The 2021 study showed that only one-third of medical students suffering from depression received appropriate treatment.
The aim of our study is to assess the impact of precariousness on the onset of psychiatric disorders and on the use or non-use of healthcare services.
Our study will involve nearly 45,000 students from PSL and UPC universities. It is based on a longitudinal cohort (via questionnaires) over three years. The aim is to identify precisely the different aspects of student precariousness (housing, transport, isolation, economic difficulties, etc.) and their link with psychological distress. The study will measure the extent of the phenomenon and identify modifiable factors that could be targeted by preventive measures. The results will enable us to better target preventive measures and propose concrete solutions to improve students' well-being and promote their success.
연구 개요
상세 설명
The COVID-19 pandemic has led to an increase in depression, particularly among young people. The French health barometer, conducted every 4-5 years by Santé Publique France (SPF), found that the prevalence of major depressive episodes (MDE) among 18-25 year olds doubled (from 11.7% to 20.8%) between 2017 and 2021. There has also been an increase in suicidal thoughts and suicide attempts. Among students, data from the 2016 Student Life Observatory (OVE) found a higher prevalence of CDE and suicidal thoughts among students than in the general population of the same age. Among the factors associated with the risk of EDC, experiencing significant financial difficulties was the main one[4]. Among medical students, a national study conducted in 2021 found that the prevalence of depression and suicidal thoughts was much higher than in the general population of the same age. Financial difficulties were also the main factor associated with the risk of depression. Indeed, students are a population that is particularly vulnerable to precariousness due to several factors. Economically, they often have limited incomes, depending on parental support, insufficient grants or precarious jobs. This exposes them to difficulties in meeting their basic needs such as housing, food and healthcare. Socially, isolation can exacerbate their situation, especially when they are far from their family network or under pressure from their studies. In addition, high academic demands, combined with unstable living conditions, impact their mental health and can contribute to the development of psychiatric disorders, which often go untreated due to a lack of affordable and accessible resources. International students are even more vulnerable due to language and administrative barriers and limited access to local support services. This multidimensional precariousness highlights the need for comprehensive support for this population, even though students are unlikely to seek professional help. In the 2021 survey, only 32% of medical students suffering from depression received adequate care. If we want to improve the health of medical students, we must not only treat disorders, but also prevent them from occurring by helping students strive for a state of well-being. In terms of prevention, the Haute Autorité de Santé (HAS) distinguishes between three levels: primary prevention, which acts upstream of the disease (on risk factors); secondary prevention, which acts at an early stage of its development (screening); and tertiary prevention, which acts on complications and the risk of recurrence.
The objectives of the study are to identify and quantify the modifiable predictive and moderating factors explaining students' psychological distress that could give rise to (primary) prevention actions by studying the various components of precariousness (housing, transport, study conditions, social isolation, grants, etc.). It also aims to study the impact of the various components of precariousness on the use and non-use of healthcare (screening and treatment, secondary and tertiary prevention).
The data will be entered directly by participants on the SKEZIA platform (https://skezi.eu/) (a solution developed by SKEZI) co-founded by AP-HP and Paris-Cité University, and will be hosted on HDS-approved servers.
Main objective:
The objective is to explore the impact of precariousness on the risk of characterised depressive episodes and the use of healthcare among PSL students (17,000 students) and UPC health faculty students (28,000 students).
Primary outcome measure:
The study will assess the 12-month prevalence of:
- characterised depressive episodes (using the Composite International Diagnostic Interview Short-Form (CIDI-SF)) and suicidal ideation in the same way as SPF and OVE;
- use of healthcare services, which will be measured in a similar way to the OVE survey and the medical student survey.
Precariousness will be assessed by the question: 'Would you say that you are currently experiencing financial difficulties?'
Secondary objectives and evaluation criteria:
The secondary objectives are to :
- evaluate the prevalence of :
- anxiety, which will be assessed using the GAD7;
- eating disorders, which will be assessed using the SCOFF;
- alcohol addiction, which will be assessed using the AUDIT, and cannabis addiction, which will be assessed using the CAST;
- burnout, using the student version, which will be assessed using the MBI-SS for pre-clinical or healthcare students and the MBI-HSS for externs and residents,
- dropout, which will be assessed by a single question as in the CNA-CORE survey,
- insomnia, which will be measured by the Insomnia Severity Index (ISI),
- loneliness, which will be assessed using the UCLA 3 items,
- harassment,
- discriminatory treatment,
- and quality of life (WHOQOL);
- identify and quantify modifiable predictive and moderating factors explaining students' psychological distress that could lead to (primary) prevention measures = by studying the various components of precariousness (housing, transport, study conditions, social isolation, grants, etc.),
- study the impact of the various components of precariousness on the use and non-use of healthcare (screening and treatment, secondary and tertiary prevention). This will be assessed using questions on the renunciation of healthcare and its causes.
연구 유형
등록 (추정된)
연락처 및 위치
연구 연락처
- 이름: Marie Benhammani-Godard
- 전화번호: 0033158411190
- 이메일: marie.godard@aphp.fr
연구 연락처 백업
- 이름: Cédric LEMOGNE, PR
- 전화번호: 00331 42 34 85 76
- 이메일: cedric.lemogne@aphp.fr
참여기준
자격 기준
공부할 수 있는 나이
- 성인
- 고령자
건강한 자원 봉사자를 받아들입니다
샘플링 방법
연구 인구
설명
Inclusion Criteria:
- Student enrolled at Paris Sciences et Lettres University (PSL, 17,000 students) or the Faculty of Health Sciences at Paris Cité University (UPC, 28,000 students),
- Aged 18 or over,
- Fluent in French,
- Affiliated to a health insurance.
Exclusion Criteria:
- Applicants under the age of 18,
- Not enrolled at PSL universities or the UPCS Faculty of Health,
- Insufficient level of French.
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
코호트 및 개입
그룹/코호트 |
개입 / 치료 |
|---|---|
|
Health students
All students enrolled at the Faculty of Health Sciences of Paris Cité University
|
설문지
|
|
Non-health students
All students enrolled at Paris Sciences and Letters University
|
설문지
|
연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
Composite International Diagnostic Interview Short-Form (CIDI-SF)
기간: Day 0
|
12-months prevalence Major Depressive Disorder and suicidal thoughts Composite International Diagnostic Interview Short-Form (CIDI-SF)
|
Day 0
|
|
Composite International Diagnostic Interview Short-Form (CIDI-SF)
기간: 12 months
|
12-months prevalence Major Depressive Disorder and suicidal thoughts Composite International Diagnostic Interview Short-Form (CIDI-SF)
|
12 months
|
|
Use of care
기간: Day 0
|
Use of care service of care professional
|
Day 0
|
|
Use of care
기간: 12 months
|
Use of care service of care professional
|
12 months
|
|
Precarity
기간: Day 0
|
Question "Would you say that you are currently experiencing financial difficulties?"
|
Day 0
|
|
Precarity
기간: 12 months
|
Question "Would you say that you are currently experiencing financial difficulties?"
|
12 months
|
2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
GAD7
기간: Day 0
|
Prevalence of anxiety
|
Day 0
|
|
GAD7
기간: 12 months
|
Prevalence of anxiety
|
12 months
|
|
GAD7
기간: 24 months
|
Prevalence of anxiety
|
24 months
|
|
SCOFF
기간: Day 0
|
Prevalence of Eating disorders
|
Day 0
|
|
SCOFF
기간: 12 months
|
Prevalence of Eating disorders
|
12 months
|
|
SCOFF
기간: 24 months
|
Prevalence of Eating disorders
|
24 months
|
|
AUDIT
기간: Day 0
|
Prevalence of Alcohol addiction
|
Day 0
|
|
AUDIT
기간: 12 months
|
Prevalence of Alcohol addiction
|
12 months
|
|
AUDIT
기간: 24 months
|
Prevalence of Alcohol addiction
|
24 months
|
|
CAST
기간: Day 0
|
Prevalence of cannabis addiction
|
Day 0
|
|
CAST
기간: 12 months
|
Prevalence of cannabis addiction
|
12 months
|
|
CAST
기간: 24 months
|
Prevalence of cannabis addiction
|
24 months
|
|
MBI-SS or MBI-HSS
기간: Day 0
|
Prevalence of Burnout using the student version : will be assessed using the MBI-SS for pre-clinical students or caregivers or Prevalence of Burnout using the student version : will be assessed using the MBI-HSS for externs and residents
|
Day 0
|
|
MBI-SS or MBI-HSS
기간: 12 months
|
Prevalence of Burnout using the student version : will be assessed using the MBI-SS for pre-clinical students or caregivers or Prevalence of Burnout using the student version : will be assessed using the MBI-HSS for externs and residents Time Frame: D0
|
12 months
|
|
MBI-SS or MBI-HSS
기간: 24 months
|
Prevalence of Burnout using the student version : will be assessed using the MBI-SS for pre-clinical students or caregivers or Prevalence of Burnout using the student version : will be assessed using the MBI-HSS for externs and residents Time Frame: D0
|
24 months
|
|
A single question as in the CNA-CORE survey
기간: Day 0
|
Prevalence of Dropout: will be assessed using a single question as in the CNA-CORE survey
|
Day 0
|
|
A single question as in the CNA-CORE survey
기간: 12 months
|
Prevalence of Dropout: will be assessed using a single question as in the CNA-CORE survey
|
12 months
|
|
A single question as in the CNA-CORE survey
기간: 24 months
|
Prevalence of Dropout: will be assessed using a single question as in the CNA-CORE survey
|
24 months
|
|
Insomnia Severity Index (ISI)
기간: Day 0
|
Prevalence of Insomnia
|
Day 0
|
|
Insomnia Severity Index (ISI)
기간: 12 months
|
Prevalence of Insomnia
|
12 months
|
|
Insomnia Severity Index (ISI)
기간: 24 months
|
Prevalence of Insomnia
|
24 months
|
|
UCLA 3 items
기간: Day 0
|
Prevalence of Loneliness
|
Day 0
|
|
UCLA 3 items
기간: 12 months
|
Prevalence of Loneliness
|
12 months
|
|
UCLA 3 items
기간: 24 months
|
Prevalence of Loneliness
|
24 months
|
|
Questions about harrassment
기간: Day 0
|
Harrassment
|
Day 0
|
|
Questions about harrassment
기간: 12 months
|
Harrassment
|
12 months
|
|
Questions about harrassment
기간: 24 months
|
Harrassment
|
24 months
|
|
Questions about discriminatory treatment
기간: Day 0
|
Discriminatory treatment
|
Day 0
|
|
Questions about discriminatory treatment
기간: 12 months
|
Discriminatory treatment
|
12 months
|
|
Questions about discriminatory treatment
기간: 24 months
|
Discriminatory treatment
|
24 months
|
|
WHOQOL
기간: Day 0
|
Quality of life
|
Day 0
|
|
WHOQOL
기간: 12 months
|
Quality of life
|
12 months
|
|
WHOQOL
기간: 24 months
|
Quality of life
|
24 months
|
|
Components of precariousness
기간: Day 0
|
Predictive and moderating factors = by studying the different components of precariousness (housing, transport, study conditions, social isolation, grants, etc.).
|
Day 0
|
|
Components of precariousness
기간: 12 months
|
Predictive and moderating factors = by studying the different components of precariousness (housing, transport, study conditions, social isolation, grants, etc.).
|
12 months
|
|
Questions on the renunciation of healthcare and its causes.
기간: 12 months
|
Impact of the various components of precariousness on the use and non-use of healthcare will be assessed using questions on the renunciation of healthcare and its causes.
|
12 months
|
|
Components of precariousness
기간: 24 months
|
Predictive and moderating factors = by studying the different components of precariousness (housing, transport, study conditions, social isolation, grants, etc.).
|
24 months
|
공동 작업자 및 조사자
연구 기록 날짜
연구 주요 날짜
연구 시작 (추정된)
기본 완료 (추정된)
연구 완료 (추정된)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (실제)
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
이 연구와 관련된 용어
키워드
추가 관련 MeSH 약관
기타 연구 ID 번호
- APHP251300
- N°IDRCB : 2025-A01968-41 (기타 식별자: France : Ministry of Health)
개별 참가자 데이터(IPD) 계획
개별 참가자 데이터(IPD)를 공유할 계획입니까?
약물 및 장치 정보, 연구 문서
미국 FDA 규제 의약품 연구
미국 FDA 규제 기기 제품 연구
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설문지에 대한 임상 시험
-
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