Internal Jugular Vein Collapsibility Index for Predicting Post-Induction Hypotension (IJV-CI)
31 juli 2026 bijgewerkt door: Elzem SEN, University of Gaziantep
The Value of Internal Jugular Vein Collapsibility Index in Predicting Hypotension Following General Anesthesia Induction in Patients Undergoing Elective Laparoscopic Cholecystectomy
This study aims to investigate whether the Internal Jugular Vein Collapsibility Index (IJV-CI), measured via ultrasonography, can predict hypotension (low blood pressure) that occurs after the induction of general anesthesia.
Researchers will measure the diameter of the internal jugular vein in patients before surgery and compare these measurements with the blood pressure changes during the first minutes of anesthesia.
The goal is to determine if IJV-CI can be used as a reliable, non-invasive tool to identify patients at higher risk of developing anesthesia-induced hypotension.
Studie Overzicht
Toestand
Nog niet aan het werven
Interventie / Behandeling
Gedetailleerde beschrijving
Patients aged 18-65 scheduled for elective laparoscopic cholecystectomy under general anesthesia will be included in the study. Exclusion criteria are as follows: Obesity (BMI > 35 kg/m²), presence of Atrial Fibrillation or serious cardiac arrhythmia, history of neck surgery or any pathology preventing internal jugular vein measurement, advanced heart failure (Ejection Fraction < 40%), severe valvular disease, peripheral vascular disease, emergency surgery, and refusal to participate in the study.
Upon arrival in the operating room, patients will be placed in a supine position. The Internal Jugular Vein (IJV) diameter will be monitored using a linear ultrasound probe during spontaneous breathing before anesthesia induction. The maximum and minimum diameters of the IJV during the respiratory cycle will be measured. The Internal Jugular Vein Collapsibility Index (IJV-CI) will be calculated using the following formula: [(IJV maximum diameter - IJV minimum diameter) / IJV maximum diameter] x 100.
Standard anesthesia induction will be performed. Non-invasive blood pressure and heart rate will be monitored and recorded at baseline (0 min), and at 1, 2, 3, 5, 7, 9, and 10 minutes following induction. Post-induction hypotension is defined as a decrease in mean arterial pressure (MAP) of more than 20% from the baseline value. The relationship between the pre-induction IJV-CI values and the development of hypotension during these specific time intervals will be statistically analyzed.
Studietype
Observationeel
Inschrijving (Geschat)
42
Contacten en locaties
In dit gedeelte vindt u de contactgegevens van degenen die het onderzoek uitvoeren en informatie over waar dit onderzoek wordt uitgevoerd.
Studiecontact
- Naam: ELZEM ŞEN, Associate Professor
- Telefoonnummer: +90 (532) 784 21 52
- E-mail: drelzem@hotmail.com
Studie Contact Back-up
- Naam: KÜBRA BAHAR TÜRKMEN, MD
- Telefoonnummer: +90 (534) 061 74 44
- E-mail: kbrabaharr@gmail.com
Studie Locaties
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Gaziantep, Turkije (Türkiye), 27310
- Gaziantep University Sahinbey Research and Training Hospital
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Contact:
- KÜBRA BAHAR TÜRKMEN, MD
- Telefoonnummer: +90 (534) 061 74 44
- E-mail: kbrabaharr@gmail.com
-
Contact:
- ELZEM ŞEN, Associate Professor
- Telefoonnummer: +90 (532) 784 21 51
- E-mail: drelzem@hotmail.com
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Hoofdonderzoeker:
- ELZEM ŞEN, Associate Professor
-
Onderonderzoeker:
- KÜBRA BAHAR TÜRKMEN, MD
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Deelname Criteria
Onderzoekers zoeken naar mensen die aan een bepaalde beschrijving voldoen, de zogenaamde geschiktheidscriteria. Enkele voorbeelden van deze criteria zijn iemands algemene gezondheidstoestand of eerdere behandelingen.
Geschiktheidscriteria
Leeftijden die in aanmerking komen voor studie
- Volwassen
- Oudere volwassene
Accepteert gezonde vrijwilligers
Nee
Bemonsteringsmethode
Niet-waarschijnlijkheidssteekproef
Studie Bevolking
The study population consists of adult patients aged 18-65 who are scheduled to undergo elective laparoscopic cholecystectomy under general anesthesia.
Participants will be selected from patients who meet the ASA I-III physical status criteria.
The study focuses on evaluating pre-induction internal jugular vein characteristics using routine clinical monitoring data in a perioperative setting.
Beschrijving
Inclusion Criteria:
- Patients aged 18-65 years.
- Patients with ASA (American Society of Anesthesiologists) physical status I, II, or III.
- Patients scheduled to receive general anesthesia.
- Patients scheduled for elective laparoscopic cholecystectomy.
Exclusion Criteria:
- Patients with obesity (Body Mass Index > 35 kg/m²).
- Patients with Atrial Fibrillation or other serious cardiac arrhythmias.
- Patients with a history of neck surgery or any pathology preventing Internal Jugular Vein (IJV) measurement.
- Patients with advanced heart failure (Ejection Fraction < 40%).
- Patients with severe valvular heart disease.
- Patients with peripheral vascular disease.
- Patients undergoing emergency surgery.
- Patients who are unwilling to participate in the study.
Studie plan
Dit gedeelte bevat details van het studieplan, inclusief hoe de studie is opgezet en wat de studie meet.
Hoe is de studie opgezet?
Ontwerpdetails
Cohorten en interventies
Groep / Cohort |
Interventie / Behandeling |
|---|---|
|
Hypotensive Group
Patients who developed post-induction hypotension (MAP decrease >20% or SBP <90 mmHg).
Pre-induction Internal Jugular Vein (IJV) ultrasonography was performed for statistical comparison.
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Pre-induction Internal Jugular Vein (IJV) measurement will be performed using a linear ultrasound probe (5-12 MHz) while the patient is in the supine position.
The IJV will be imaged in the transverse plane at the level of the cricoid cartilage.
During spontaneous breathing, the maximum and minimum diameters of the vein will be recorded.
The Collapsibility Index (IJV-CI) will be calculated using these measurements.
This non-invasive assessment is performed immediately before the induction of general anesthesia to evaluate its predictive value for post-induction hypotension.
Andere namen:
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Non-hypotensive Group
Patients aged 18-65 scheduled for elective laparoscopic cholecystectomy who remained hemodynamically stable (no MAP decrease >20% or SBP <90 mmHg) after standard anesthesia induction.
Pre-induction IJV measurement was performed to evaluate its predictive capacity."
|
Pre-induction Internal Jugular Vein (IJV) measurement will be performed using a linear ultrasound probe (5-12 MHz) while the patient is in the supine position.
The IJV will be imaged in the transverse plane at the level of the cricoid cartilage.
During spontaneous breathing, the maximum and minimum diameters of the vein will be recorded.
The Collapsibility Index (IJV-CI) will be calculated using these measurements.
This non-invasive assessment is performed immediately before the induction of general anesthesia to evaluate its predictive value for post-induction hypotension.
Andere namen:
|
Wat meet het onderzoek?
Primaire uitkomstmaten
Uitkomstmaat |
Maatregel Beschrijving |
Tijdsspanne |
|---|---|---|
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Internal Jugular Vein Collapsibility Index (IJV-CI)
Tijdsspanne: Baseline (pre-induction) and every minute up to 10 minutes following induction or until surgical in
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Hypotension is defined as a decrease in Mean Arterial Pressure (MAP) of more than 20% from the baseline value.
The predictive value of pre-induction IJV-CI for this occurrence will be assessed.Measurements will be recorded at 0, 1, 2, 3, 5, 7, 9, and 10 minutes following induction, but will stop if surgical incision occurs earlier than 10 minutes
|
Baseline (pre-induction) and every minute up to 10 minutes following induction or until surgical in
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Medewerkers en onderzoekers
Hier vindt u mensen en organisaties die betrokken zijn bij dit onderzoek.
Sponsor
Onderzoekers
- Hoofdonderzoeker: ELZEM ŞEN, Associate Professor, Gaziantep University, Faculty of Medicine, Department of Anesthesiology and Reanimation
Studie record data
Deze datums volgen de voortgang van het onderzoeksdossier en de samenvatting van de ingediende resultaten bij ClinicalTrials.gov. Studieverslagen en gerapporteerde resultaten worden beoordeeld door de National Library of Medicine (NLM) om er zeker van te zijn dat ze voldoen aan specifieke kwaliteitscontrolenormen voordat ze op de openbare website worden geplaatst.
Bestudeer belangrijke data
Studie start (Geschat)
15 augustus 2026
Primaire voltooiing (Geschat)
1 januari 2027
Studie voltooiing (Geschat)
1 februari 2027
Studieregistratiedata
Eerst ingediend
27 april 2026
Eerst ingediend dat voldeed aan de QC-criteria
27 april 2026
Eerst geplaatst (Werkelijk)
4 mei 2026
Updates van studierecords
Laatste update geplaatst (Werkelijk)
3 augustus 2026
Laatste update ingediend die voldeed aan QC-criteria
31 juli 2026
Laatst geverifieerd
1 juli 2026
Meer informatie
Termen gerelateerd aan deze studie
Trefwoorden
Aanvullende relevante MeSH-voorwaarden
Andere studie-ID-nummers
- 2026/217
Plan Individuele Deelnemersgegevens (IPD)
Bent u van plan om gegevens van individuele deelnemers (IPD) te delen?
NEE
Beschrijving IPD-plan
Individual participant data will not be shared to protect patient confidentiality and privacy in accordance with local ethical committee guidelines and institutional data protection policies.
Informatie over medicijnen en apparaten, studiedocumenten
Bestudeert een door de Amerikaanse FDA gereguleerd geneesmiddel
Nee
Bestudeert een door de Amerikaanse FDA gereguleerd apparaatproduct
Nee
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