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Ultrasound-Guided Transversalis Fascia Plane Block Versus Quadratus Lumborum Plane Block for Analgesia After Appendectomy in Pediatrics
Ultrasound-Guided Transversalis Fascia Plane Block Versus Quadratus Lumborum Plane Block for Analgesia After Appendectomy in Pediatrics: A Prospective Randomized Study
This study aims to compare the effectiveness of ultrasound-guided Transversalis Fascia Plane block versus Quadratus Lumborum block for postoperative pain relief in pediatrics undergoing appendectomy.
Primary outcomes:
• Proportion of patients needing rescue analgesia within the first 24 postoperative hours.
Secondary outcomes:
- Visual Analogue Scale pain intensity measurements.
- Intraoperative Heart rate and mean arterial blood pressure will be recorded.
- Time to first analgesic request for patients needing rescue analgesia (Fentanyl).
- Block-related complications (e.g., hematoma, local anesthetic toxicity, lower limb weakness).
- Parents' satisfaction score.
Studie Overzicht
Toestand
Interventie / Behandeling
Gedetailleerde beschrijving
Appendicectomy is amongst the most commonly performed surgery, with acute appendicitis being the most frequent reason for abdominal surgical emergencies in the world . The lifetime risk of appendicitis is 7-8%, with rising incidence in the newly industrialized countries . The prevailing treatment of choice for appendicitis is appendicectomy, which can be performed either 'open' or laparoscopically .
A major contributor to the pain experienced by a patient after abdominal surgery is the incision made in the abdominal wall . Almost 80% of patients undergoing surgery experience postoperative pain, and 80% of them reported moderate-to-severe pain intensity .
Traditional methods of postoperative pain management in children, such as systemic opioids and nonsteroidal anti-inflammatory drugs , may not always provide adequate relief, especially for more invasive procedures . These approaches can also be associated with side effects like sedation, nausea, and respiratory depression, which may complicate postoperative care and recovery . In recent years, regional anesthesia techniques have emerged as promising alternatives for postoperative pain management in various surgical populations Two specific regional blocks that have gained attention for their potential benefits in reducing postoperative pain after abdominal surgeries is the Quadratus Lumborum Block and the Transversus Facial Abdominal Plane block The Quadratus Lumborum Block targets the nerves supplying the lumbar plexus, providing analgesia to the anterior abdominal wall . It has been shown to be effective in adult patients undergoing lower abdominal surgery, offering improved postoperative pain scores and reduced opioid consumption compared to traditional pain management strategies .
Although, both Quadratus Lumborum Block and Transversus Facial Abdominal Plane block are frequently employed in pediatric anesthesia, evidence to guide clinical decisions on which block offers superior outcomes needs to be comprehensively reviewed. We aimed to compare the effectiveness of ultrasound-guided Transversalis Fascia Plane block versus Quadratus Lumborum block for postoperative pain relief in pediatrics undergoing appendectomy.
This study aims to compare the effectiveness of ultrasound-guided Transversalis Fascia Plane block versus Quadratus Lumborum block for postoperative pain relief in pediatrics undergoing appendectomy.
Primary outcomes:
• Proportion of patients needing rescue analgesia within the first 24 postoperative hours.
Secondary outcomes:
- Visual Analogue Scale pain intensity measurements.
- Intraoperative Heart rate and mean arterial blood pressure will be recorded.
- Time to first analgesic request for patients needing rescue analgesia (Fentanyl).
- Block-related complications (e.g., hematoma, local anesthetic toxicity, lower limb weakness).
- Parents' satisfaction score.
Studietype
Inschrijving (Geschat)
Fase
- Niet toepasbaar
Contacten en locaties
Studie Locaties
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Tanta, Egypte
- Tanta university
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Deelname Criteria
Geschiktheidscriteria
Leeftijden die in aanmerking komen voor studie
- Kind
Accepteert gezonde vrijwilligers
Beschrijving
Inclusion Criteria:
- 70 patients aged between 7 and 12 years of both sexes undergoing appendectomy, American Society of Anesthesiologists (ASA) physical status of I or II
Exclusion Criteria:
- Refusal of parents to participate
- Patients with peritonitis
- History of allergy to bupivacaine and other amide local anesthetics
- Infection at the site of block needle entry
- Bleeding diathesis
- Neurological disorders
- American Society of Anesthesiologists ≥ III
Studie plan
Hoe is de studie opgezet?
Ontwerpdetails
- Primair doel: Preventie
- Toewijzing: Gerandomiseerd
- Interventioneel model: Parallelle opdracht
- Masker: Dubbele
Wapens en interventies
Deelnemersgroep / Arm |
Interventie / Behandeling |
|---|---|
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Experimenteel: Group I: Transversalis Fascia Plane Block versus
Patients will receive general anesthesia and ultrasound-guided transversalis fascia plane block in a dose of 0.4 ml/kg of 0.25% bupivacaine administered prior to surgical excision
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35 Patients will receive general anesthesia and ultrasound-guided transversalis fascia plane block in a dose of 0.4 ml/kg of 0.25% bupivacaine administered prior to surgical excision.
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Experimenteel: Group II :Quadratus Lumborum Plane Block
patients will receive general anesthesia and a quadratus lumborum plane block in a dose of 0.4 ml/kg of 0.25% bupivacaine administered prior to surgical excision.
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35 patients will receive general anesthesia and a quadratus lumborum plane block in a dose of 0.4 ml/kg of 0.25% bupivacaine administered prior to surgical excision
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Wat meet het onderzoek?
Primaire uitkomstmaten
Uitkomstmaat |
Tijdsspanne |
|---|---|
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Proportion of patients needing rescue analgesia
Tijdsspanne: within the first 24 postoperative hours.
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within the first 24 postoperative hours.
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Secundaire uitkomstmaten
Uitkomstmaat |
Maatregel Beschrijving |
Tijdsspanne |
|---|---|---|
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Visual Analogue Scale
Tijdsspanne: 24 postoperative hours
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Visual Analogue Scale pain intensity measurements.
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24 postoperative hours
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Medewerkers en onderzoekers
Sponsor
Studie record data
Bestudeer belangrijke data
Studie start (Werkelijk)
Primaire voltooiing (Werkelijk)
Studie voltooiing (Geschat)
Studieregistratiedata
Eerst ingediend
Eerst ingediend dat voldeed aan de QC-criteria
Eerst geplaatst (Werkelijk)
Updates van studierecords
Laatste update geplaatst (Werkelijk)
Laatste update ingediend die voldeed aan QC-criteria
Laatst geverifieerd
Meer informatie
Termen gerelateerd aan deze studie
Trefwoorden
Andere studie-ID-nummers
- 36264MS975/6/25
Plan Individuele Deelnemersgegevens (IPD)
Bent u van plan om gegevens van individuele deelnemers (IPD) te delen?
Beschrijving IPD-plan
IPD delen Ondersteunend informatietype
- LEERPROTOCOOL
- SAP
- ICF
Informatie over medicijnen en apparaten, studiedocumenten
Bestudeert een door de Amerikaanse FDA gereguleerd geneesmiddel
Bestudeert een door de Amerikaanse FDA gereguleerd apparaatproduct
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Klinische onderzoeken op Quadratus Lumborum-blok
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Alexandria UniversityVoltooidTransmusculaire Quadratus Lumborum Block HeupoperatieEgypte
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Assiut UniversityWervingQuadratus Lumborum-blokEgypte
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Tanta UniversityWervingQuadratus Lumborum-blokEgypte
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Ostfold Hospital TrustVoltooidQuadratus Lumborum-blok | CholecystectomieNoorwegen
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Cairo UniversityOnbekendQuadratus Lumborum-blok | OnderbuikchirurgieEgypte
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Konya Necmettin Erbakan ÜniversitesiVoltooidTotale heupoperatie | Pericapsulaire zenuw | Quadratus LumborumKalkoen
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University of California, Los AngelesBeëindigdLaparoscopische myomectomie | Quadratus Lumborum zenuwblokkadeVerenigde Staten
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Ain Shams UniversityWervingLaparoscopische cholecystectomie | Quadratus Lumborum-blok | Gemodificeerde Thoracoabdominale zenuwblokkadeEgypte
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Port Said University hospitalVoltooidErector Spinae vliegtuigblok | Quadratus Lumborum-blok | Sleeve gastrectomieEgypte
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Zagazig UniversityVoltooidLaparoscopische cholecystectomie | Erector Spinae vliegtuigblok | Quadratus Lumborum-blokEgypte
Klinische onderzoeken op Transversalis Fascia Plane Block group
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Istanbul Training and Research HospitalWerving
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Alexandria UniversityVoltooidPijn, postoperatief | Ontwikkelingsdysplasie van de heup | Regionale anesthesie morbiditeitEgypte
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Tanta UniversityWervingKeizersnede | Transversalis Fascia Plane-blok | Intrathecaal DexmedetomidineEgypte
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Cairo UniversityVoltooidPostoperatieve pijn, acuutEgypte
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The Fourth Affiliated Hospital of China Medical...Onbekend
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Dr Abdurrahman Yurtaslan Ankara Oncology Training...VoltooidPijn, postoperatief | Pijnbeheersing | Artropathie van de knie | Vroege AmbulanceTurkije (Türkiye)
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Samsun UniversityVoltooidKeizersnede | Acuut pijnbeheerKalkoen
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Ataturk UniversityVoltooid
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Ondokuz Mayıs UniversityGiresun Training and Research HospitalNog niet aan het wervenRegionale anesthesie | Postoperatieve pijnbehandeling | Transversalis Fascia Plane-blok | Inguinale hernia eenzijdig
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Sahiwal medical college sahiwalWervingBradycardie | Postoperatieve analgesie | Hypotensie door medicijnen geïnduceerdPakistan