Ultrasound-Guided Transversalis Fascia Plane Block Versus Quadratus Lumborum Plane Block for Analgesia After Appendectomy in Pediatrics
Ultrasound-Guided Transversalis Fascia Plane Block Versus Quadratus Lumborum Plane Block for Analgesia After Appendectomy in Pediatrics: A Prospective Randomized Study
This study aims to compare the effectiveness of ultrasound-guided Transversalis Fascia Plane block versus Quadratus Lumborum block for postoperative pain relief in pediatrics undergoing appendectomy.
Primary outcomes:
• Proportion of patients needing rescue analgesia within the first 24 postoperative hours.
Secondary outcomes:
- Visual Analogue Scale pain intensity measurements.
- Intraoperative Heart rate and mean arterial blood pressure will be recorded.
- Time to first analgesic request for patients needing rescue analgesia (Fentanyl).
- Block-related complications (e.g., hematoma, local anesthetic toxicity, lower limb weakness).
- Parents' satisfaction score.
調査の概要
状態
詳細な説明
Appendicectomy is amongst the most commonly performed surgery, with acute appendicitis being the most frequent reason for abdominal surgical emergencies in the world . The lifetime risk of appendicitis is 7-8%, with rising incidence in the newly industrialized countries . The prevailing treatment of choice for appendicitis is appendicectomy, which can be performed either 'open' or laparoscopically .
A major contributor to the pain experienced by a patient after abdominal surgery is the incision made in the abdominal wall . Almost 80% of patients undergoing surgery experience postoperative pain, and 80% of them reported moderate-to-severe pain intensity .
Traditional methods of postoperative pain management in children, such as systemic opioids and nonsteroidal anti-inflammatory drugs , may not always provide adequate relief, especially for more invasive procedures . These approaches can also be associated with side effects like sedation, nausea, and respiratory depression, which may complicate postoperative care and recovery . In recent years, regional anesthesia techniques have emerged as promising alternatives for postoperative pain management in various surgical populations Two specific regional blocks that have gained attention for their potential benefits in reducing postoperative pain after abdominal surgeries is the Quadratus Lumborum Block and the Transversus Facial Abdominal Plane block The Quadratus Lumborum Block targets the nerves supplying the lumbar plexus, providing analgesia to the anterior abdominal wall . It has been shown to be effective in adult patients undergoing lower abdominal surgery, offering improved postoperative pain scores and reduced opioid consumption compared to traditional pain management strategies .
Although, both Quadratus Lumborum Block and Transversus Facial Abdominal Plane block are frequently employed in pediatric anesthesia, evidence to guide clinical decisions on which block offers superior outcomes needs to be comprehensively reviewed. We aimed to compare the effectiveness of ultrasound-guided Transversalis Fascia Plane block versus Quadratus Lumborum block for postoperative pain relief in pediatrics undergoing appendectomy.
This study aims to compare the effectiveness of ultrasound-guided Transversalis Fascia Plane block versus Quadratus Lumborum block for postoperative pain relief in pediatrics undergoing appendectomy.
Primary outcomes:
• Proportion of patients needing rescue analgesia within the first 24 postoperative hours.
Secondary outcomes:
- Visual Analogue Scale pain intensity measurements.
- Intraoperative Heart rate and mean arterial blood pressure will be recorded.
- Time to first analgesic request for patients needing rescue analgesia (Fentanyl).
- Block-related complications (e.g., hematoma, local anesthetic toxicity, lower limb weakness).
- Parents' satisfaction score.
研究の種類
入学 (推定)
段階
- 適用できない
連絡先と場所
研究場所
-
-
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Tanta、エジプト
- Tanta University
-
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参加基準
適格基準
就学可能な年齢
- 子
健康ボランティアの受け入れ
説明
Inclusion Criteria:
- 70 patients aged between 7 and 12 years of both sexes undergoing appendectomy, American Society of Anesthesiologists (ASA) physical status of I or II
Exclusion Criteria:
- Refusal of parents to participate
- Patients with peritonitis
- History of allergy to bupivacaine and other amide local anesthetics
- Infection at the site of block needle entry
- Bleeding diathesis
- Neurological disorders
- American Society of Anesthesiologists ≥ III
研究計画
研究はどのように設計されていますか?
デザインの詳細
- 主な目的:防止
- 割り当て:ランダム化
- 介入モデル:並列代入
- マスキング:ダブル
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
|
実験的:Group I: Transversalis Fascia Plane Block versus
Patients will receive general anesthesia and ultrasound-guided transversalis fascia plane block in a dose of 0.4 ml/kg of 0.25% bupivacaine administered prior to surgical excision
|
35 Patients will receive general anesthesia and ultrasound-guided transversalis fascia plane block in a dose of 0.4 ml/kg of 0.25% bupivacaine administered prior to surgical excision.
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実験的:Group II :Quadratus Lumborum Plane Block
patients will receive general anesthesia and a quadratus lumborum plane block in a dose of 0.4 ml/kg of 0.25% bupivacaine administered prior to surgical excision.
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35 patients will receive general anesthesia and a quadratus lumborum plane block in a dose of 0.4 ml/kg of 0.25% bupivacaine administered prior to surgical excision
|
この研究は何を測定していますか?
主要な結果の測定
結果測定 |
時間枠 |
|---|---|
|
Proportion of patients needing rescue analgesia
時間枠:within the first 24 postoperative hours.
|
within the first 24 postoperative hours.
|
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Visual Analogue Scale
時間枠:24 postoperative hours
|
Visual Analogue Scale pain intensity measurements.
|
24 postoperative hours
|
協力者と研究者
スポンサー
研究記録日
主要日程の研究
研究開始 (実際)
一次修了 (実際)
研究の完了 (推定)
試験登録日
最初に提出
QC基準を満たした最初の提出物
最初の投稿 (実際)
学習記録の更新
投稿された最後の更新 (実際)
QC基準を満たした最後の更新が送信されました
最終確認日
詳しくは
本研究に関する用語
その他の研究ID番号
- 36264MS975/6/25
個々の参加者データ (IPD) の計画
個々の参加者データ (IPD) を共有する予定はありますか?
IPD プランの説明
IPD 共有サポート情報タイプ
- STUDY_PROTOCOL
- SAP
- ICF
医薬品およびデバイス情報、研究文書
米国FDA規制医薬品の研究
米国FDA規制機器製品の研究
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方形腰ブロックの臨床試験
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Konya Necmettin Erbakan Üniversitesi完了
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Kafrelsheikh University募集
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Riphah International Universityまだ募集していませんQuadratus Lumborumパキスタン
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medina medical center完了腹腔鏡下胆嚢摘出術 | 術後鎮痛 | 超音波ガイド付き | Quadratus Lumborumエジプト
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National Cancer Institute, Egypt募集術後の痛み | がん患者 | 超音波 | 開腹腎摘出術 | 二国間 | 筋肉内クアドラタスlumborum平面ブロック | 横方向の四肢lumborum平面ブロックエジプト
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Aalborg University Hospital終了しました痛みの治療 | ロボット支援腹腔鏡手術 | Bilateral Dual Transversus Abdominis Plane Blockデンマーク
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Erzurum Regional Training & Research Hospital募集
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Antalya City Hospitalまだ募集していません術後の痛み | 局所麻酔 | 腹腔鏡下子宮摘出術 | インタートランスバースプロセスブロック | Mtapa Block
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Antalya City Hospitalまだ募集していません術後の痛み | 腹腔鏡下胆嚢摘出術 | 局所麻酔 | インタートランスバースプロセスブロック | Mtapa Block
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Antalya City Hospitalまだ募集していません術後の痛み | 局所麻酔 | 横筋筋膜平面ブロック | 腹腔鏡下鼠径ヘルニア修復 | Mtapa Block
Transversalis Fascia Plane Block groupの臨床試験
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Erzurum Regional Training & Research Hospital完了
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Chinese PLA General Hospitalまだ募集していません痛み、術後 | 局所麻酔 | 腹横筋面ブロック(TAPブロック)
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London Health Sciences Centre Research Institute...募集