Prognostic Value of Pulse Oximetry Differences
Prognostic Significance of Multi-site Pulse Oximetry Differences in Dyspneic Emergency Department Patients
Studie Overzicht
Toestand
Conditie
Gedetailleerde beschrijving
This is a prospective observational cohort study conducted in a single ED to evaluate the prognostic significance of inter-site differences in pulse oximetry in adult patients presenting with dyspnea.
Adult patients (≥19 years) presenting with dyspnea and classified as Korean Triage and Acuity Scale (KTAS) levels 1-3 will be enrolled at the time of ED admission. During initial vital sign assessment at ED presentation, SpO₂ will be simultaneously measured at the finger, earlobe, and forehead, along with the corresponding perfusion index at each site.
The primary exposure of interest is the difference between finger and earlobe SpO₂ (ΔSpO₂). Additional inter-site SpO₂ differences involving forehead measurements will also be evaluated. Clinical and physiological data at presentation will be collected prospectively, while outcome data will be obtained through retrospective medical record review.
The primary outcome is the mean difference in ΔSpO₂ between patients with poor outcomes-defined as all-cause mortality from ED admission to hospital discharge or intensive care unit (ICU) admission-and those with favorable outcomes. Secondary outcomes include the associations of ΔSpO₂ with mortality, ICU admission, endotracheal intubation, serum lactate levels, and perfusion index, as well as the predictive performance of ΔSpO₂ using logistic regression and receiver operating characteristic (ROC) analysis. The prognostic value of ΔSpO₂ will also be compared with established early warning scores such as NEWS.
Studietype
Inschrijving (Geschat)
Contacten en locaties
Studiecontact
- Naam: Stephen GW LEE, MD
- Telefoonnummer: 82-10-5124-8415
- E-mail: leestephengyungwon@yuhs.ac
Studie Locaties
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Seoul
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Seoul, Seoul, Zuid -Korea, 03722
- Werving
- Yonsei University Severance Hospital
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Contact:
- Stephen GW LEE, MD
- Telefoonnummer: 82-2-2228-2678
- E-mail: LEESTEPHENGYUNGWON@YUHS.AC
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Deelname Criteria
Geschiktheidscriteria
Leeftijden die in aanmerking komen voor studie
- Volwassen
- Oudere volwassene
Accepteert gezonde vrijwilligers
Bemonsteringsmethode
Studie Bevolking
Beschrijving
Inclusion Criteria:
- Adult patients aged 19 years or older presenting to the emergency department with dyspnea, classified as KTAS level 1-3
Exclusion Criteria:
- Patients in whom SpO₂ measurements were not obtained simultaneously
- Patients in whom arterial blood gas analysis was not ordered at initial evaluation
- Pregnant patients
- Patients with facial trauma or hand trauma
- Patients with amputation, injury, or burns at the measurement sites
- Patients wearing nail polish
- Patients with dyshemoglobinemia
- Non-Korean nationality
- Patients who did not provide consent to participate in the study
Studie plan
Hoe is de studie opgezet?
Ontwerpdetails
Cohorten en interventies
Groep / Cohort |
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Dyspnea cohort
Patients visiting emergency department with dyspnea who are categorized to KTAS 1-3
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Wat meet het onderzoek?
Primaire uitkomstmaten
Uitkomstmaat |
Maatregel Beschrijving |
Tijdsspanne |
|---|---|---|
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In-hospital mortality or ICU admission
Tijdsspanne: From the index emergency department visit through hospital discharge, assessed up to 6 months.
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In-hospital mortality or ICU admission of index visit
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From the index emergency department visit through hospital discharge, assessed up to 6 months.
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Medewerkers en onderzoekers
Sponsor
Studie record data
Bestudeer belangrijke data
Studie start (Werkelijk)
Primaire voltooiing (Geschat)
Studie voltooiing (Geschat)
Studieregistratiedata
Eerst ingediend
Eerst ingediend dat voldeed aan de QC-criteria
Eerst geplaatst (Werkelijk)
Updates van studierecords
Laatste update geplaatst (Werkelijk)
Laatste update ingediend die voldeed aan QC-criteria
Laatst geverifieerd
Meer informatie
Termen gerelateerd aan deze studie
Aanvullende relevante MeSH-voorwaarden
Andere studie-ID-nummers
- 4-2025-1489
- 6-2025-0076 (Ander subsidie-/financieringsnummer: Yonsei University College of Medicine)
Plan Individuele Deelnemersgegevens (IPD)
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Beschrijving IPD-plan
Informatie over medicijnen en apparaten, studiedocumenten
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