Effects of Virtual Reality After Liver Transplantation (VR-LT)
Effects of Virtual Reality on Pain, Fatigue and Vital Signs After Liver Transplantation A Randomized Controlled Trial
This randomized controlled study aims to evaluate the effects of a virtual reality intervention on pain, fatigue and vital signs in patients during the early postoperative period after liver transplantation. Postoperative symptoms such as pain and fatigue may negatively affect recovery and patient comfort. Virtual reality has emerged as a non-pharmacological method that may help reduce these symptoms by providing distraction and relaxation.
A total of 84 patients were randomly assigned to an experimental group or a control group. The experimental group received a 20-minute virtual reality session, while the control group received standard care. Pain, fatigue and vital signs were measured before and after the intervention.
This study aims to determine whether virtual reality can improve patient comfort and physiological stability and support recovery after liver transplantation.
Visão geral do estudo
Status
Condições
Intervenção / Tratamento
Descrição detalhada
This study was designed as a prospective, randomized controlled, single-blind trial to evaluate the effects of a virtual reality intervention on pain, fatigue, and vital signs in patients during the early postoperative period after liver transplantation.
Liver transplantation is a life-saving procedure; however, patients frequently experience postoperative symptoms such as pain and fatigue, which may negatively affect recovery, physiological stability, and overall patient comfort. Non-pharmacological interventions have gained increasing attention in recent years as supportive approaches to improve postoperative outcomes. Virtual reality is an emerging technology that provides immersive distraction and relaxation, potentially reducing symptom perception and enhancing patient well-being.
The study was conducted in the organ transplantation clinic of a university hospital between May 2025 and January 2026. A total of 84 patients who met the inclusion criteria were randomly assigned to either the experimental group (n=42) or the control group (n=42) using a computer-based randomization method.
Patients in the experimental group received a 20-minute virtual reality intervention during the early postoperative period, while patients in the control group received standard care without additional intervention. Pain levels were assessed using the Numerical Rating Scale (NRS), fatigue levels were measured using the Brief Fatigue Inventory (BFI), and vital signs including heart rate, respiratory rate, and blood pressure were recorded. All measurements were obtained before the intervention and 15 minutes after the intervention.
The primary objective of the study was to determine the effect of virtual reality on fatigue levels. Secondary outcomes included pain and vital signs. Data were analysed using appropriate statistical methods, and statistical significance was set at p<0.05.
This study aims to contribute to the evidence base regarding the effectiveness of virtual reality as a non-pharmacological nursing intervention and to support its integration into clinical practice to improve postoperative care in liver transplantation patients.
Tipo de estudo
Inscrição (Real)
Estágio
- Não aplicável
Contactos e Locais
Locais de estudo
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Malatya, Turquia (Türkiye)
- Inonu University Liver Transplantation Institute
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Critérios de participação
Critérios de elegibilidade
Idades elegíveis para estudo
- Adulto
- Adulto mais velho
Aceita Voluntários Saudáveis
Descrição
Inclusion Criteria:
- Age ≥18 years
- Underwent liver transplantation
- In the early postoperative period
- Able to communicate verbally
- No diagnosed psychiatric disorder
- Hemodynamically stable
- Pain score ≥4 on the Numerical Rating Scale (NRS)
- Willing to participate in the study
Exclusion Criteria:
- Presence of severe postoperative complications
- Cognitive impairment or inability to understand instructions
- Visual or hearing impairments preventing use of virtual reality
- History of motion sickness or vertigo related to virtual reality use
- Chronic diseases that may affect fatigue or vital signs (e.g., uncontrolled cardiovascular or respiratory diseases)
- Refusal to participate
Plano de estudo
Como o estudo é projetado?
Detalhes do projeto
- Finalidade Principal: Tratamento
- Alocação: Randomizado
- Modelo Intervencional: Atribuição Paralela
- Mascaramento: Solteiro
Armas e Intervenções
Grupo de Participantes / Braço |
Intervenção / Tratamento |
|---|---|
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Experimental: Experimental Group
Participants received a 20 minute virtual reality intervention during the early postoperative period following liver transplantation.
The intervention was administered using a head mounted display and aimed to reduce fatigue and improve physiological parameters
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A 20 minute immersive virtual reality session was administered using a headmounted display during the early postoperative period following liver transplantation.
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Comparador Ativo: Control Group
Participants received routine postoperative care without any additional intervention
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Participants received routine postoperative care without any additional intervention
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O que o estudo está medindo?
Medidas de resultados primários
Medida de resultado |
Descrição da medida |
Prazo |
|---|---|---|
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Change in fatigue severity
Prazo: Baseline and 15 minutes after intervention
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Change in fatigue severity measured using the Brief Fatigue Inventory (BFI) total score (range: 0-10; higher scores indicate greater fatigue)
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Baseline and 15 minutes after intervention
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Medidas de resultados secundários
Medida de resultado |
Descrição da medida |
Prazo |
|---|---|---|
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Change in pain intensity
Prazo: Baseline and 15 minutes after intervention
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Measured using the Numerical Rating Scale (NRS) (range: 0-10; higher scores indicate greater pain)
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Baseline and 15 minutes after intervention
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Change in heart rate (beats per minute)
Prazo: Baseline and 15 minutes after intervention
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Change in heart rate measured in beats per minute (bpm).
Heart rate was recorded as part of routine vital sign monitoring to evaluate the physiological response to the virtual reality intervention.
Lower values may indicate improved relaxation and autonomic stability.
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Baseline and 15 minutes after intervention
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Change in systolic and diastolic blood pressure (mmHg)
Prazo: Baseline and 15 minutes after intervention
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Change in systolic and diastolic blood pressure measured in millimeters of mercury (mmHg).
Blood pressure was recorded as part of routine vital sign monitoring to evaluate the cardiovascular response to the virtual reality intervention.
Lower values may indicate improved physiological stability and relaxation.
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Baseline and 15 minutes after intervention
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Change in systolic and diastolic blood pressure (mmHg)
Prazo: Baseline and 15 minutes after intervention
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Change in systolic and diastolic blood pressure measured in millimeters of mercury (mmHg).
Blood pressure was assessed as part of routine vital sign monitoring to evaluate the cardiovascular response to the intervention.
Lower values may indicate improved physiological stability.
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Baseline and 15 minutes after intervention
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Colaboradores e Investigadores
Patrocinador
Datas de registro do estudo
Datas Principais do Estudo
Início do estudo (Real)
Conclusão Primária (Real)
Conclusão do estudo (Real)
Datas de inscrição no estudo
Enviado pela primeira vez
Enviado pela primeira vez que atendeu aos critérios de CQ
Primeira postagem (Real)
Atualizações de registro de estudo
Última Atualização Postada (Real)
Última atualização enviada que atendeu aos critérios de controle de qualidade
Última verificação
Mais Informações
Termos relacionados a este estudo
Termos MeSH relevantes adicionais
- Dor
- Manifestações Neurológicas
- Complicações pós-operatórias
- Processos Patológicos
- Condições Patológicas, Sinais e Sintomas
- Sinais e sintomas
- Dor, Pós-operatório
- Fadiga
- Administração de Serviços de Saúde
- Qualidade, acesso e avaliação da assistência médica
- Qualidade de assistência médica
- Indicadores de qualidade, assistência médica
- Padrão de atendimento
Outros números de identificação do estudo
- 25H04 (Número de outro subsídio/financiamento: Malatya Turgut Ozal University Scientific Research Projects Unit)
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