Random Whole Body Vibration over 5 Weeks Leads to Effects Similar to Placebo: A Controlled Study in Parkinson's Disease

Heiko Gaßner, Annette Janzen, Ansgar Schwirtz, Petra Jansen, Heiko Gaßner, Annette Janzen, Ansgar Schwirtz, Petra Jansen

Abstract

Background. Random whole body vibration (WBV) training leads to beneficial short-term effects in patients with Parkinson's disease (PD). However, the effect of WBV lasting several weeks is not clear. Objectives. The aim of this study was to assess a random WBV training over 5 weeks in PD. Methods. Twenty-one participants with PD were allocated to either an experimental or a placebo group matched by age, gender, and Hoehn&Yahr stage. The WBV training consisted of 5 series, 60 s each. In the placebo group, vibration was simulated. The primary outcome was the change of performance in Functional reach test (FRT), step-walk-turn task, biomechanical Gait Analysis, Timed up and go test (TUG), and one leg stance. Findings. In most of the parameters, there was no significant interaction of "time∗group." Both groups improved significantly in Gait parameters, TUG, and one leg stance. Only in the FRT [F(1,15) = 8.397; P < 0.05] and in the TUG [F(1,15) = 4.971; P < 0.05] the experimental group performed significantly better than the placebo group. Conclusions. Random WBV training over 5 weeks seems to be less effective than reported in previous studies performing short-term training. The slight improvements in the FRT and TUG are not clinically relevant.

Figures

Figure 1
Figure 1
Flow diagram.
Figure 2
Figure 2
(a) Visualization of the Functional Reach Test (FRT) and calculation of the Center of Pressure (CoP) to the normalized foot length in %. The horizontal distance between heel marker and toe marker was defined as 100%. (b) Test set-up for the intervention. Both groups stood on the vibration platform with knees slightly bend. The placebo group had additionally to concentrate on the light on the wall.
Figure 3
Figure 3
Results of the intrasession evaluation in the “Timed up and go test” (TUG (a)) and the “one leg stance test” (b). TUG: significant interaction “time∗group”; one leg stance: significant main effect of factor “time” (*P < 0.05).

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Source: PubMed

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