Impact of Spirulina maxima Intake and Exercise (SIE) on Metabolic and Fitness Parameters in Sedentary Older Adults with Excessive Body Mass: Study Protocol of a Randomized Controlled Trial

Marco Antonio Hernández-Lepe, José de Jesús Manríquez-Torres, Omar Ramos-Lopez, Aracely Serrano-Medina, Melinna Ortiz-Ortiz, Jorge Alberto Aburto-Corona, María Del Pilar Pozos-Parra, Luis Eduardo Villalobos-Gallegos, Genaro Rodríguez-Uribe, Luis Mario Gómez-Miranda, Marco Antonio Hernández-Lepe, José de Jesús Manríquez-Torres, Omar Ramos-Lopez, Aracely Serrano-Medina, Melinna Ortiz-Ortiz, Jorge Alberto Aburto-Corona, María Del Pilar Pozos-Parra, Luis Eduardo Villalobos-Gallegos, Genaro Rodríguez-Uribe, Luis Mario Gómez-Miranda

Abstract

Life expectancy has increased unprecedentedly in recent decades, benefiting the longevity of the world's population. The most frequent pathological conditions presented in this age group include excessive body fat, frailty, and hypercholesterolemia. These pathological characteristics condition general health and autonomy in adults to carry out their usual activities. In this sense, the search for a healthy lifestyle is necessary, consisting in a healthy diet that includes supplementation with nutraceuticals and the daily practice of physical activity. This study protocol aims to evaluate the independent and synergistic effect of 12 weeks of Spirulina maxima intake (5 g/day), with or without an exercise program on metabolic and fitness parameters of 52 sedentary older adults with excessive body mass in a double-blind, randomized, crossover, controlled trial design. The main findings from this trial will provide novel evidence for future interventions designed for the elderly population and the result will be disseminated through peer-reviewed journals and international meetings. ClinicalTrials.gov identification number: NCT04658875 (Effect of Spirulina maxima and Exercise on General Fitness and Blood Lipids in Older Adults).

Keywords: Arthrospira maxima; dyslipidemia; elderly; obesity; physical exercise; randomized trial.

Conflict of interest statement

All authors declare that they have no conflicts of interest concerning this investigation, who have completed the International Committee of Medical Journal Editors (ICMJE) Format for Disclosure of Potential Conflicts of Interest, available at http://www.icmje.org/conflicts-of-interest/. The funders had no role in the study’s design; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

Figures

Figure 1
Figure 1
Flow diagram of the experimental design for the impact of Spirulina maxima intake and exercise (SIE) trial. Same color indicates the same group of participants.

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