Intra-articular radioactive yttrium and triamcinolone hexacetonide: an inconclusive trial. Arthritis and Rheumatism Council Multicentre Radiosynoviorthesis Trial Group
Abstract
A restricted sequential design multicentre controlled trial of yttrium-90 against triamcinolone intra-articularly was undertaken in patients with rheumatoid arthritis with knee involvement. The trial had to be discontinued because of dwindling recruitment over time. The reasons for this and other features contributing to an inconclusive outcome are noted. This experience lends little encouragement to the idea that yttrium-90 therapy is more or less advantageous than triamcinolone hexacetonide.
References
- Q J Med. 1973 Apr;42(166):357-67
- Lancet. 1975 Mar 1;1(7905):488-9
- C R Acad Sci Hebd Seances Acad Sci D. 1974 Sep 16;279(12):1051-4
- Ann Rheum Dis. 1983 Apr;42(2):132-7
- Rheumatol Rehabil. 1979 May;18(2):65-77
- Rheumatol Rehabil. 1979 May;18(2):78-84
- Scand J Rheumatol. 1981;10(3):234-6
- Scand J Rheumatol. 1977;6(4):209-12
Source: PubMed