Use of the Hospital Anxiety and Depression Scale and the Taiwanese Depression Questionnaire for screening depression in head and neck cancer patients in Taiwan

Yu Lee, Yi-Shan Wu, Chih-Yen Chien, Fu-Min Fang, Chi-Fa Hung, Yu Lee, Yi-Shan Wu, Chih-Yen Chien, Fu-Min Fang, Chi-Fa Hung

Abstract

Objective: The purposes of this study are 1) to estimate the prevalence of common mental disorders including depressive disorder in patients with head and neck cancer (HNC) at baseline and at the 6-month follow-up and 2) to test the validity of two self-reported questionnaires, the Hospital Anxiety and Depression Scale (HADS) and the Taiwanese Depression Questionnaire (TDQ), for screening depression in patients with HNC.

Methods: Participants were recruited from the outpatient collaborative care clinic for HNC of a tertiary hospital in Taiwan between January 2010 and January 2011. Ninety-three patients with HNC were enrolled and assessed using the HADS, TDQ, and Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, fourth edition, Patient edition, at baseline and at the 6-month follow-up. Conventional validity indices of the HADS and TDQ were examined.

Results: Our results showed that the validity of the TDQ was satisfactory and comparable to that of both the HADS depression subscale and the HADS total scale. The cutoff scores of the HADS and TDQ for screening possible depressive disorders were 8 and 15, respectively. The areas under the receiver operating characteristic curve of the HADS and TDQ were mean 0.975±0.015 and 0.966±0.019, respectively. Thirteen participants (14%) were diagnosed with depressive disorders at the 6-month follow-up, compared with 8.5% at baseline.

Conclusion: Our results indicate that both the HADS and TDQ are valid instruments for screening depression in patients with HNC.

Keywords: Hospital Anxiety and Depression Scale; Taiwanese Depression Questionnaire; head and neck cancer; prevalence; validity.

Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Receiver operating characteristic curve and optimal cutoff score for the TDQ, the HADS-T, and the HADS-D among patients with head and neck cancer. Abbreviations: TDQ, Taiwanese Depression Questionnaire; HADS, Hospital Anxiety and Depression Scale; HADS-D, HADS depressive subscale; HADS-T, HADS total scale; ROC, receiver operating characteristic.

References

    1. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010;127(12):2893–2917.
    1. Tarver T. Cancer Facts & Figures 2012. American Cancer Society (ACS) J Consum Health Internet. 2012;16(3):366–367.
    1. Health Promotion Administration Taiwan cancer registry [Online] 2013
    1. Chen YJ, Chang JT, Liao CT, et al. Head and neck cancer in the betel quid chewing area: recent advances in molecular carcinogenesis. Cancer Sci. 2008;99(8):1507–1514.
    1. Haisfield-Wolfe ME, McGuire DB, Soeken K, Geiger-Brown J, De Forge BR. Prevalence and correlates of depression among patients with head and neck cancer: a systematic review of implications for research. Oncol Nurs Forum. 2009;36(3):E107–E125.
    1. Archer J, Hutchison I, Korszun A. Mood and malignancy: head and neck cancer and depression. J Oral Pathol Med. 2008;37(5):255–270.
    1. Duffy SA, Ronis DL, Valenstein M, et al. Depressive symptoms, smoking, drinking, and quality of life among head and neck cancer patients. Psychosomatics. 2007;48(2):142–148.
    1. Katz MR, Kopek N, Waldron J, Devins GM, Tomlinson G. Screening for depression in head and neck cancer. Psychooncology. 2004;13(4):269–280.
    1. Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67(6):361–370.
    1. Mitchell AJ, Meader N, Symonds P. Diagnostic validity of the Hospital Anxiety and Depression Scale (HADS) in cancer and palliative settings: a meta-analysis. J Affect Disord. 2010;126(3):335–348.
    1. Özalp E, Soygür H, Cankurtaran E, Turhan L, Akbiyik D, Geyik P. Psychiatric morbidity and its screening in Turkish women with breast cancer: a comparison between the HADS and SCID tests. Psychooncology. 2008;17(7):668–675.
    1. Juang KD, Wang SJ, Lin CH, Fuh JL. Use of the hospital anxiety and depression scale as a screening tool for patients with headache. Zhonghua Yi Xue Za Zhi (Taipei) 1999;62(11):749–755.
    1. Wang GL, Hsu SH, Feng AC, et al. The HADS and the DT for screening psychosocial distress of cancer patients in Taiwan. Psychooncology. 2011;20(6):639–646.
    1. Lee Y, Yang MJ, Lai TJ, Chiu NM, Chau TT. Development of the Taiwanese Depression Questionnaire. Chang Gung Med J. 2000;23(11):688–694.
    1. Lee Y, Lin PY, Hsu ST, Cing-Chi Y, Yang LC, Wen JK. Comparing the use of the Taiwanese Depression Questionnaire and Beck Depression Inventory for screening depression in patients with chronic pain. Chang Gung Med J. 2008;31(4):369–377.
    1. Chen KC, Yang YK, Lee IH, Yeh TL, Lu RB, Chen PS. Sexual dysfunction and physicians’ perception in medicated patients with major depression in Taiwan. Depress Anxiety. 2008;25(9):E56–E62.
    1. Wang LJ, Chen CK, Hsu SC, Lee SY, Wang CS, Yeh WY. Active job, healthy job? Occupational stress and depression among hospital physicians in Taiwan. Ind Health. 2011;49(2):173–184.
    1. Yen YC, Rebok GW, Yang MJ, Lung FW. A multilevel analysis of the influence of Apolipoprotein E genotypes on depressive symptoms in late-life moderated by the environment. Prog Neuropsychopharmacol Biol Psychiatry. 2008;32(2):479–486.
    1. Kursat S, Colak HB, Toraman A, Ekmekci C, Tekce H, Alici T. The relationship between depression–malnutrition and echocardiographic-blood pressure parameters in chronic hemodialysis patients. Int Urol Nephrol. 2008;40(3):793–799.
    1. Tu CH, Hsu MC, Chi SC, Lin HY, Yen YC. Routine depression screening and diagnosing strategy for cancer inpatients. Psychooncology. 2014;23(9):1057–1067.
    1. Geisser ME, Roth RS, Robinson ME. Assessing depression among persons with chronic pain using the Center for Epidemiological Studies-Depression Scale and the Beck Depression Inventory: a comparative analysis. Clin J Pain. 1997;13(2):163–170.
    1. Wesley AL, Gatchel RJ, Polatin PB, Kinney RK, Mayer TG. Differentiation between somatic and cognitive/affective components in commonly used measurements of depression in patients with chronic low-back pain: let’s not mix apples and oranges. Spine (Phila Pa 1976) 1991;16(6 suppl):S213–S215.
    1. First MB, Spitzer RL, Gibbon M, Williams JB. User’s Guide for the Structured Clinical Interview for DSM-IV Axis I Disorders SCID-I: Clinician Version. Arlington, VA: American Psychiatric Pub; 1997.
    1. Hsiao JK, Bartko JJ, Potter WZ. Diagnosing diagnoses: receiver operating characteristic methods and psychiatry. Arch Gen Psychiatry. 1989;46(7):664–667.
    1. Hanley JA, McNeil BJ. A method of comparing the areas under receiver operating characteristic curves derived from the same cases. Radiology. 1983;148(3):839–843.
    1. Kugaya A, Akechi T, Okuyama T, et al. Prevalence, predictive factors, and screening for psychologic distress in patients with newly diagnosed head and neck cancer. Cancer. 2000;88(12):2817–2823.
    1. Mitchell AJ, Chan M, Bhatti H, et al. Prevalence of depression, anxiety, and adjustment disorder in oncological, haematological, and palliative-care settings: a meta-analysis of 94 interview-based studies. Lancet Oncol. 2011;12(2):160–174.
    1. Gilbert J, Haman KL, Dietrich MS, Blakely RD, Shelton RC, Murphy BA. Depression in patients with head and neck cancer and a functional genetic polymorphism of the serotonin transporter gene. Head Neck. 2012;34(3):359–364.
    1. McCaffrey JC, Weitzner M, Kamboukas D, Haselhuhn G, Lamonde L, Booth-Jones M. Alcoholism, depression, and abnormal cognition in head and neck cancer: a pilot study. Otolaryngol Head Neck Surg. 2007;136(1):92–97.
    1. Morton RP, Davies AD, Baker J, Baker GA, Stell PM. Quality of life in treated head and neck cancer patients: a preliminary report. Clin Otolaryngol Allied Sci. 1984;9(3):181–185.
    1. Bjelland I, Dahl AA, Haug TT, Neckelmann D. The validity of the Hospital Anxiety and Depression Scale: an updated literature review. J Psychosom Res. 2002;52(2):69–77.
    1. Kugaya A, Akechi T, Okuyama T, Okamura H, Uchitomi Y. Screening for psychological distress in Japanese cancer patients. Jpn J Clin Oncol. 1998;28(5):333–338.
    1. Love AW, Grabsch B, Clarke DM, Bloch S, Kissane DW. Screening for depression in women with metastatic breast cancer: a comparison of the Beck Depression Inventory Short Form and the Hospital Anxiety and Depression Scale. Aust N Z J Psychiatry. 2004;38(7):526–531.
    1. Holland JC, Breitbart WS, Jacobsen PB, Lederberg MS, Loscalzo MJ, McCorkle R. Psycho-Oncology. Oxford: Oxford University Press; 2010.
    1. Tsuang MT, Tohen M, Gep Z. Textbook in Psychiatric Epidemiology. New York, NY: Wiley; 1995. pp. 229–242.
    1. Hueng TT, Lee IH, Guog YJ, et al. Is a patient – administered depression rating scale valid for detecting cognitive deficits in patients with major depressive disorder? Psychiatry Clin Neurosci. 2011;65(1):70–76.
    1. Yang M, Moon C. Neurotoxicity of cancer chemotherapy. Neural Regen Res. 2013;8(17):1606–1614.
    1. Savard J, Villa J, Ivers H, Simard S, Morin CM. Prevalence, natural course, and risk factors of insomnia comorbid with cancer over a 2-month period. J Clin Oncol. 2009;27(31):5233–5239.

Source: PubMed

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