Treating Sleep Problems in Patients with Schizophrenia

Felicity Waite, Elissa Myers, Allison G Harvey, Colin A Espie, Helen Startup, Bryony Sheaves, Daniel Freeman, Felicity Waite, Elissa Myers, Allison G Harvey, Colin A Espie, Helen Startup, Bryony Sheaves, Daniel Freeman

Abstract

Background: Sleep disturbance is increasingly recognized as a major problem for patients with schizophrenia but it is rarely the direct focus of treatment. The main recommended treatment for insomnia is cognitive behavioural therapy, which we have been evaluating for patients with current delusions and hallucinations in the context of non-affective psychosis.

Aims: In this article we describe the lessons we have learned about clinical presentations of sleep problems in schizophrenia and the adaptations to intervention that we recommend for patients with current delusions and hallucinations.

Method: Twelve factors that may particularly contribute to sleep problems in schizophrenia are identified. These include delusions and hallucinations interfering with sleep, attempts to use sleep as an escape from voices, circadian rhythm disruption, insufficient daytime activity, and fear of the bed, based upon past adverse experiences. Specific adaptations for psychological treatment related to each factor are described.

Conclusions: Our experience is that patients want help to improve their sleep; sleep problems in schizophrenia should be treated with evidence-based interventions, and that the interventions may have the added benefit of lessening the psychotic experiences. A treatment technique hierarchy is proposed for ease of translation to clinical practice.

Keywords: Psychosis; cognitive behavioural therapy; delusions; hallucinations; insomnia.

Figures

Figure 1.
Figure 1.
A hierarchy of treatment technique

References

    1. Borbély A. A. (1982). A two process model of sleep regulation. Human Neurobiology, 1, 195–204.
    1. Cohrs S. (2008). Sleep disturbances in patients with schizophrenia. CNS Drugs, 22, 939–962. doi:10.2165/00023210-200822110-00004
    1. Espie C. A. (2006). Overcoming Insomnia and Sleep Problems: a self help guide using cognitive behavioural techniques. London: Constable and Robinson.
    1. Espie C. A., Broomfield N. M., MacMahon K. M. A., MacPhee L. M. and Taylor L. M. (2006). The attention-intention-effort pathway in the development of psychophysiologic insomnia. Sleep Medicine Reviews. doi:10.1016/j.smrv.2006.03.002
    1. Foresight Mental Capital and Wellbeing Project. (2008). Foresight Mental Capital and Wellbeing Project Final Project Report. London: Government Office for Science.
    1. Freeman D., Dunn G., Startup H., Pugh K., Cordwell J., Mander H., et al. (2015). Effects of cognitive behaviour therapy for worry on persecutory delusions in patients with psychosis (WIT). Lancet Psychiatry, 2, 305–313.
    1. Freeman D., Pugh K., Vorontsova N. and Southgate L. (2009). Insomnia and paranoia. Schizophrenia Research, 108(1–3), 280–284. doi:10.1016/j.schres.2008.12.001
    1. Freeman D., Startup H., Myers E., Harvey A., Geddes J., Yu L.-M., et al. (2013). The effects of using cognitive behavioural therapy to improve sleep for patients with delusions and hallucinations (the BEST study). Trials, 14, 214. doi:10.1186/1745-6215-14-214
    1. Freeman D., Waite F., Startup H., Myers E., Lister R., McInerney J., et al. (in press). A randomised controlled pilot trial testing the effects of cognitive behavioural therapy to improve sleep for patients with persistent delusions and hallucinations: the Better Sleep Trial (BEST). Lancet Psychiatry.
    1. Harvey A. G. (2002). A cognitive model of insomnia. Behaviour Research and Therapy, 40, 869–93.
    1. Myers E., Startup H. and Freeman D. (2011). Cognitive behavioural treatment of insomnia in individuals with persistent persecutory delusions. Journal of Behavior Therapy and Experimental Psychiatry, 42, 330–336. doi:10.1016/j.jbtep.2011.02.004
    1. Sheaves B., Onwumere J., Keen N., Stahl D. and Kuipers E. (in press). Nightmares in patients with psychosis. Canadian Journal of Psychiatry.
    1. Waite F., Evans N., Myers E., Startup H., Lister R., Harvey A. G., et al. (in press). The patient experience of sleep problems and their treatment in the context of current delusions and hallucinations. Psychology and Psychotherapy: Theory, Research and Practice.
    1. Wulff K., Dijk D.-J., Middleton B., Foster R. G. and Joyce E. M. (2012). Sleep and circadian rhythm disruption in schizophrenia. British Journal of Psychiatry, 200, 308–316. doi:10.1192/bjp.bp.111.096321

Source: PubMed

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