Cytokine Storms: Understanding COVID-19
Nilam Mangalmurti, Christopher A Hunter, Nilam Mangalmurti, Christopher A Hunter
Abstract
The elevated circulating levels of cytokines associated with a variety of infectious and immune-mediated conditions are frequently termed a cytokine storm. Here, we explain the protective functions of cytokines in "ideal" responses; the multi-factorial origins that can drive these responses to become pathological; and how this ultimately leads to vascular damage, immunopathology, and worsening clinical outcomes.
Copyright © 2020 Elsevier Inc. All rights reserved.
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References
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Source: PubMed