Vancouver At Home: pragmatic randomized trials investigating Housing First for homeless and mentally ill adults

Julian M Somers, Michelle L Patterson, Akm Moniruzzaman, Lauren Currie, Stefanie N Rezansoff, Anita Palepu, Karen Fryer, Julian M Somers, Michelle L Patterson, Akm Moniruzzaman, Lauren Currie, Stefanie N Rezansoff, Anita Palepu, Karen Fryer

Abstract

Background: Individuals with mental illnesses are overrepresented among the homeless. Housing First (HF) has been shown to promote positive outcomes in this population. However, key questions remain unresolved, including: how to match support services to client needs, the benefits of housing in scattered sites versus single congregate building, and the effectiveness of HF with individuals actively using substances. The present study aimed to recruit two samples of homeless mentally ill participants who differed in the complexity of their needs. Study details, including recruitment, randomization, and follow-up, are presented.

Methods: Eligibility was based on homeless status and current mental disorder. Participants were classified as either moderate needs (MN) or high needs (HN). Those with MN were randomized to HF with Intensive Case Management (HF-ICM) or usual care. Those with HN were randomized to HF with Assertive Community Treatment (HF-ACT), congregate housing with support, or usual care. Participants were interviewed every 3 months for 2 years. Separate consent was sought to access administrative data.

Results: Participants met eligibility for either MN (n = 200) or HN (n = 297) and were randomized accordingly. Both samples were primarily male and white. Compared to participants designated MN, HN participants had higher rates of hospitalization for psychiatric reasons prior to randomization, were younger at the time of recruitment, younger when first homeless, more likely to meet criteria for substance dependence, and less likely to have completed high school. Across all study arms, between 92% and 100% of participants were followed over 24 months post-randomization. Minimal significant differences were found between study arms following randomization. 438 participants (88%) provided consent to access administrative data.

Conclusion: The study successfully recruited participants meeting criteria for homelessness and current mental disorder. Both MN and HN groups had high rates of substance dependence, suicidality, and physical illness. Randomization resulted in no meaningful detectable differences between study arms.

Trial registration: Current Controlled Trials: ISRCTN57595077 (Vancouver at Home study: Housing First plus Assertive Community Treatment versus congregate housing plus supports versus treatment as usual) and ISRCTN66721740 (Vancouver At Home study: Housing First plus Intensive Case Management versus treatment as usual).

Figures

Figure 1
Figure 1
Participant flow through eligibility, screening, needs level assessment, and allocation to study arm. αIncludes approximately 100 participants deemed ineligible via an informal telephone screen, and 94 participants who were ineligible after formal in-person screening. βIncludes 11 participants who were unable to be located after assignment or left within 1 month of entering.

References

    1. Goering PN, Streiner DL, Adair C, Aubry T, Barker J, Distasio J, Hwang SW, Komaroff J, Latimer E, Somers J, Zabkiewicz DM. The At Home/Chez Soi trial protocol: a pragmatic, multi-site, randomised controlled trial of a Housing First intervention for homeless individuals with mental illness in five Canadian cities. BMJ Open. 2011;1:e000323–e000323. doi: 10.1136/bmjopen-2011-000323.
    1. Campbell L, Boyd N, Culburt L. A Thousand Dreams: Vancouver’s Downtown Eastside and the Fight for its Future. Vancouver, BC: Greystone Books; 2009.
    1. Foley D. Hellish conditions at single-room occupancy hotels. Body Posit. 1998;11:18–23.
    1. Shannon K, Ishida T, Lai C, Tyndall MW. The impact of unregulated single room occupancy hotels on the health status of illicit drug users in Vancouver. Int J Drug Policy. 2006;17:107–114. doi: 10.1016/j.drugpo.2005.09.002.
    1. Kerr T, Tyndall M, Li K, Montaner J, Wood E. Safer injection facility use and syringe sharing in injection drug users. Lancet. 2005;366:316–318. doi: 10.1016/S0140-6736(05)66475-6.
    1. Harvey E, Strathdee SA, Patrick DM, Ofner M, Archibald CP, Eades G, O’Shaughnessy MV. A qualitative investigation into an HIV outbreak among injection drug users in Vancouver, British Columbia. AIDS Care. 1998;10:313–321. doi: 10.1080/713612412.
    1. Palepu A, Tyndall MW, Leon H, Muller J, O’Shaughnessy MV, Schechter MT, Anis AH. Hospital utilization and costs in a cohort of injection drug users. CMAJ. 2001;165:415–420.
    1. Strathdee SA, Patrick DM, Archibald CP, Ofner M, Cornelisse PGA, Rekart M, Schechter MT, O’Shaughnessy MV. Social determinants predict needle-sharing behaviour among injection drug users in Vancouver, Canada. Addict. 1997;92:1339–1348. doi: 10.1111/j.1360-0443.1997.tb02852.x.
    1. Kushel MB, Perry S, Bangsberg D, Clark R, Moss AR. Emergency department use among the homeless and marginally housed: results from a community-based study. Am J Public Health. 2002;92:778–784. doi: 10.2105/AJPH.92.5.778.
    1. Gilmer TP, Stefancic A, Ettner SL, Manning WG, Tsemberis S. Effect of full-service partnerships on homelessness, use and costs of mental health services, and quality of life among adults with serious mental illness. Arch Gen Psychiatry. 2010;67:645–652. doi: 10.1001/archgenpsychiatry.2010.56.
    1. Gulcur L, Stefancic A, Shinn M, Tsemberis S, Fischer SN. Housing, hospitalization, and cost outcomes for homeless individuals with psychiatric disabilities participating in continuum of care and housing first programmes. J Comm App Soc Psychol. 2003;13:171–186. doi: 10.1002/casp.723.
    1. Yanos PT, Felton BJ, Tsemberis S, Frye VA. Exploring the role of housing type, neighborhood characteristics, and lifestyle factors in the community integration of formerly homeless persons diagnosed with mental illness. J Ment Health. 2007;16:703–717. doi: 10.1080/09638230701496378.
    1. Siegel C, Samuels J, Tang D-I, Berg I, Jones K, Hopper K. Tenant outcomes in supported housing and community residences in New York City. Psychiatr Serv. 2006;57:982–991. doi: 10.1176/appi.ps.57.7.982.
    1. Tsemberis S, Eisenberg RF. Pathways to housing: supported housing for street-dwelling homeless individuals with psychiatric disabilities. Psychiatr Serv. 2000;51:487–493. doi: 10.1176/appi.ps.51.4.487.
    1. Stein LI, Test MA. Alternative to mental hospital treatment. I. Conceptual model, treatment program, and clinical evaluation. Arch Gen Psychiatry. 1980;37:392–397. doi: 10.1001/archpsyc.1980.01780170034003.
    1. Bond G, Drake R, Mueser K, Latimer E. Assertive community treatment for people with severe mental illness: critical ingredients and impact on patients. Dis Manag Health Outcomes. 2001;9:141–159. doi: 10.2165/00115677-200109030-00003.
    1. Marshall M, Lockwood A. Assertive Community Treatment for People with Severe Mental Disorders. Chichester: John Wiley & Sons; 1998.
    1. Lipton FR, Siegel C, Hannigan A, Samuels J, Baker S. Tenure in supportive housing for homeless persons with severe mental illness. Psychiatr Serv. 2000;51:479–486. doi: 10.1176/appi.ps.51.4.479.
    1. Fichter MM, Quadflieg N. Intervention effects of supplying homeless individuals with permanent housing: a 3-year prospective study. Acta Psychiatr Scand. 2006;113:36–40.
    1. Wong Y-LI, Hadley TR, Culhane DP, Poulin SR, Davis MR, Cirksey BA, Brown JL. Predicting Staying in or Leaving Permanent Supportive Housing that Serves Homeless People with Serious Mental Illness. US Department of Housing and Urban Development: Washington, DC; 2006.
    1. Larimer ME, Malone DK, Garner MD, Atkins DC, Burlingham B, Lonczak HS, Tanzer K, Ginzler J, Clifasefi SL, Hobson WG, Marlatt GA. Health care and public service use and costs before and after provision of housing for chronically homeless persons with severe alcohol problems. JAMA. 2009;301:1349–1357. doi: 10.1001/jama.2009.414.
    1. Schutt RK. Homelessness, Housing, and Mental Illness. Cambridge, MA: Harvard University Press; 2011.
    1. Schutt RK, Hough RL, Goldfinger SM, Lehman AF, Shern DL, Valencia E, Wood PA. Lessening homelessness among persons with mental illness: A comparison of five randomized treatment trials. Asian J, Psychiatry. 2009;2:100–105. doi: 10.1016/j.ajp.2009.07.003.
    1. Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, Hergueta T, Baker R, Dunbar GC. The Mini-International Neuropsychiatric Interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry. 1998;59:20–33. doi: 10.4088/JCP.v59n0105.
    1. Barker S, Barron ND, McFarland BH, Bigelow DD, Carnahan TM. A community ability scale for chronically mentally Ill consumers: Part II. Applications. Community Ment Health J. 1994;30:459–472. doi: 10.1007/BF02189063.
    1. Khandor EE, Mason KK, Chambers CC, Rossiter KK, Cowan LL, Hwang SWS. Access to primary health care among homeless adults in Toronto, Canada: results from the Street Health survey. Open Med. 2011;5:e94–e103.
    1. Hwang SW, Ueng JJM, Chiu S, Kiss A, Tolomiczenko G, Cowan L, Levinson W, Redelmeier DA. Universal health insurance and health care access for homeless persons. Am J Public Health. 2010;100:1454–1461. doi: 10.2105/AJPH.2009.182022.
    1. Felitti VJ, Anda RF, Nordenberg D, Williamson DF, Spitz AM, Edwards V, Koss MP, Marks JS. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. Am J Prev Med. 1998;14:245–258. doi: 10.1016/S0749-3797(98)00017-8.
    1. Benedict RHB, Schretlen D, Groninger L, Brandt J. Hopkins Verbal Learning Test – Revised: Normative data and analysis of inter-form and test-retest reliability. Clin Neuropsychol. 1998;12:43–55. doi: 10.1076/clin.12.1.43.1726.
    1. Brandt J. The hopkins verbal learning test: Development of a new memory test with six equivalent forms. Clin Neuropsychol. 1991;5:125–142. doi: 10.1080/13854049108403297.
    1. Reitan RM. Validity of the trail making test as an indicator of organic brain damage. Percept Mot Skills. 1958;8:271–276.
    1. Wechsler D. Wechsler Adult Intelligence Scale. 4. London: Pearson; 2008.
    1. Aubry T, Myner J. Community integration and quality of life: a comparison of persons with psychiatric disabilities in housing programs and community residents who are neighbors. Can J Commun Ment Health. 1996;15:5–20.
    1. Segal SP, Aviram U. The Mentally Ill in Community-Based Sheltered Care. Chichester: John Wiley & Sons; 1978.
    1. Chavis DM, Hogge JH, McMillan DW, Wandersman A. Sense of community through Brunswick’s lens: A first look. J Community Psychol. 1986;14:24–40. doi: 10.1002/1520-6629(198601)14:1<24::AID-JCOP2290140104>;2-P.
    1. Boothroyd RA, Chen HJ. The psychometric properties of the Colorado Symptom Index. Adm Policy Ment Health. 2008;35:370–378. doi: 10.1007/s10488-008-0179-6.
    1. Shern DL, Wilson NZ, Coen AS, Patrick DC, Foster M, Bartsch DA, Demmler J. Client outcomes II: Longitudinal client data from the Colorado treatment outcome study. Milbank Q. 1994;72:123–148. doi: 10.2307/3350341.
    1. Conrad KJ, Yagelka JR, Matters MD, Rich AR, Williams V, Buchanan M. Reliability and validity of a modified Colorado Symptom Index in a national homeless sample. Ment Health Serv Res. 2001;3:141–153. doi: 10.1023/A:1011571531303.
    1. Greenwood RM, Schaefer-McDaniel NJ, Winkel G, Tsemberis SJ. Decreasing psychiatric symptoms by increasing choice in services for adults with histories of homelessness. Am J Community Psychol. 2005;36:223–238. doi: 10.1007/s10464-005-8617-z.
    1. Straus MA, Hamby SL, Boney-McCoy S, Sugarman DB. The Revised Conflict Tactics Scales (CTS2): Development and preliminary psychometric data. J Fam Issues. 1996;17:283–316. doi: 10.1177/019251396017003001.
    1. Mares AS, Greenberg GA, Rosenheck RA. HUD/HHS/VA Collaborative Initiative to Help End Chronic Homelessness: National Performance Outcomes Assessment: Is System Integration Associated with Client Outcomes? West Haven, CT: Northeast Program Evaluation Center; 2007.
    1. Adair CE, McDougall GM, Mitton CR, Joyce AS, Wild TC, Gordon A, Costigan N, Kowalsky L, Pasmeny G, Beckie A. Continuity of care and health outcomes among persons with severe mental illness. Psychiatr Serv. 2005;56:1061–1069. doi: 10.1176/appi.ps.56.9.1061.
    1. Maruish ME. The Use of Psychological Testing for Treatment Planning and Outcomes Assessment. London: Routledge: Instruments for Adults. 3rd edition; 2004.
    1. Goering P. Making a Difference: Ontario’s Community Mental Health Evaluation Initiative. Community Mental Health Evaluation Initiative: Toronto, ON; 2004.
    1. Lamers LM, Bouwmans CAM, van Straten A, Donker MCH, Hakkaart L. Comparison of EQ-5D and SF-6D utilities in mental health patients. Health Econ. 2006;15:1229–1236. doi: 10.1002/hec.1125.
    1. EuroQol Group. EuroQol A new facility for the measurement of health-related quality of life. Health Policy. 1990;16:199–208.
    1. Brooks R. EuroQol: the current state of play. Health Policy. 1996;37:53–72. doi: 10.1016/0168-8510(96)00822-6.
    1. Dickens CM, McGowan L, Percival C, Douglas J, Tomenson B, Cotter L, Heagerty A, Creed FH. Lack of a close confidant, but not depression, predicts further cardiac events after myocardial infarction. Heart. 2004;90:518–522. doi: 10.1136/hrt.2003.011668.
    1. United States Department of Agriculture (USDA) USDA Adult Food Security Survey Module. Washington, DC: USDA; 2008.
    1. Dennis ML, Chan Y-F, Funk RR. Development and validation of the GAIN Short Screener (GSS) for internalizing, externalizing and substance use disorders and crime/violence problems among adolescents and adults. Am J Addict. 2006;15:80–91. doi: 10.1080/10550490601006055.
    1. Dennis ML, White MK, Titus JC, Unsicker JI. Global Appraisal of Individual Needs (GAIN) Bloomington, IL: Chestnut Health Systems: Administration Guide for the GAIN and Related Measures (Version 5); 2006.
    1. Guerriere DN, Ungar WJ, Corey M, Croxford R, Tranmer JE, Tullis E, Coyte PC. Evaluation of the ambulatory and home care record: Agreement between self-reports and administrative data. J of Inter Tech of Health Care. 2006;22:203–210.
    1. Kashner TM, Stensland MD, Lind L, Wicker A, Rush AJ, Golden RM, Henley SS. Measuring use and cost of care for patients with mood disorders. Med Care. 2009;47:184–190. doi: 10.1097/MLR.0b013e31818457b8.
    1. Sirey JA, Meyers BS, Teresi JA, Bruce ML, Ramirez M, Raue PJ, Perlick DA, Holmes D. The Cornell Service Index as a measure of health service use. Psychiatr Serv. 2005;56:1564–1569. doi: 10.1176/appi.ps.56.12.1564.
    1. Browne GB, Arpin K, Corey P, Fitch M, Gafni A. Individual correlates of health service utilization and the cost of poor adjustment to chronic illness. Med Care. 1990;28:43–58. doi: 10.1097/00005650-199001000-00006.
    1. Forchuk C, Brown SA, Schofield R, Jensen E. Perceptions of health and health service utilization among homeless and housed psychiatric consumer/survivors. J Psychiatr Ment Health Nurs. 2008;15:399–407. doi: 10.1111/j.1365-2850.2007.01246.x.
    1. Chisholm D. Client Socio-Demographic and Service Receipt Inventory - European Version: development of an instrument for international research: EPSILON Study 5. Br J Psychiatry. 2000;177:28s–33. doi: 10.1192/bjp.177.39.s28.
    1. Tsemberis SJ, Moran L, Shinn M, Asmussen SM, Shern DL. Consumer preference programs for individuals who are homeless and have psychiatric disabilities: a drop-in center and a supported housing program. Am J Community Psychol. 2003;32:305–317.
    1. Toro PA, Passero Rabideau JM, Bellavia CW, Daeschler CV, Wall DD, Thomas DM, Smith SJ. Evaluating an intervention for homeless persons: results of a field experiment. J Consult Clin Psychol. 1997;65:476–484.
    1. Dickerson FB, Origoni AE, Pater A, Friedman BK, Kordonski WM. An expanded version of the Multnomah Community Ability Scale: anchors and interview probes for the assessment of adults with serious mental illness. Community Ment Health J. 2003;39:131–137. doi: 10.1023/A:1022610620391.
    1. Sheehan DV, Lecrubier Y, Harnett Sheehan K, Janavs J, Weiller E, Keskiner A, Schinka J, Knapp E, Sheehan MF, Dunbar GC. The validity of the Mini International Neuropsychiatric Interview (MINI) according to the SCID-P and its reliability. Eur Psychiatry. 1997;12:232–241. doi: 10.1016/S0924-9338(97)83297-X.
    1. Lecrubier Y, Sheehan DV, Weiller E, Amorim P, Bonora I, Harnett Sheehan K, Janavs J, Dunbar GC. The Mini International Neuropsychiatric Interview (MINI). A short diagnostic structured interview: reliability and validity according to the CIDI. Eur Psychiatry. 1997;12:224–231. doi: 10.1016/S0924-9338(97)83296-8.
    1. Amorim P, Lecrubier Y, Weiller E, Hergueta T, Sheehan D. DSM-IH-R Psychotic Disorders: procedural validity of the Mini International Neuropsychiatric Interview (MINI). Concordance and causes for discordance with the CIDI. Eur Psychiatry. 1998;13:26–34. doi: 10.1016/S0924-9338(97)86748-X.
    1. Nasreddine ZSZ, Phillips NAN, Bédirian VV, Charbonneau SS, Whitehead VV, Collin II, Cummings JLJ, Chertkow HH. The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc. 2005;53:695–699. doi: 10.1111/j.1532-5415.2005.53221.x.
    1. Lehman AF. Measures of quality of life among persons with severe and persistent mental disorders. Soc Psychiatry Psychiatr Epidemiol. 1996;31:78–88. doi: 10.1007/BF00801903.
    1. Uttaro T, Lehman A. Graded response modeling of the Quality of Life Interview. Eval Program Plann. 1999;22:41–52. doi: 10.1016/S0149-7189(98)00039-1.
    1. Lancon CC, Auquier PP, Launois RR, Toumi MM, Llorca PMP, Bebbington PP, Lehman AA. [Evaluation of the quality of life of schizophrenic patients: validation of the brief version of the Quality of Life Interview] Encephale. 2000;26:11–16.
    1. Giffort D, Schmook A, Woody C, Vollendorf C, Gervain M. Construction of a Scale to Measure Consumer Recovery. Office of Mental Health: Springfield, IL; 1995.
    1. Corrigan PW, Giffort D, Rashid F, Leary M, Okeke I. Recovery as a psychological construct. Community Ment Health J. 1999;35:231–239. doi: 10.1023/A:1018741302682.
    1. Corrigan PW, Salzer M, Ralph RO, Sangster Y, Keck L. Examining the factor structure of the recovery assessment scale. Schizophr Bull. 2004;30:1035–1041. doi: 10.1093/oxfordjournals.schbul.a007118.
    1. Tsemberis S, McHugo G, Williams V, Hanrahan P, Stefancic A. Measuring homelessness and residential stability: The residential time-line follow-back inventory. Am J Community Psychol. 2007;35:29–42. doi: 10.1002/jcop.20132.
    1. Ware JJ, Kosinski MM, Keller SDS. A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care. 1996;34:220–233. doi: 10.1097/00005650-199603000-00003.
    1. Larson CO. Use of the SF-12 instrument for measuring the health of homeless persons. Health Serv Res. 2002;37:733–750. doi: 10.1111/1475-6773.00046.
    1. Marsden J, Gossop M, Stewart D, Best D, Farrell M, Lehmann P, Edwards C, Strang J. The Maudsley Addiction Profile (MAP): a brief instrument for assessing treatment outcome. Addiction. 1998;93:1857–1867. doi: 10.1046/j.1360-0443.1998.9312185711.x.
    1. Latimer J, Morton-Bourgon K, Chrétien JA. A Meta-Analytic Examination of Drug Treatment Courts: Do they Reduce Recidivism? Department of Justice Canada: Ottawa, ON; 2006.
    1. Horvath AO, Greenberg LS. Development and validation of the Working Alliance Inventory. J Couns Psychol. 1989;36:223–233.
    1. Horvath AO, Greenberg LS. (Eds): The Working Alliance: Theory, Research, and Practice. Chichester: John Wiley & Sons; 1994.
    1. Tracey TJ, Kokotovic AM. Factor structure of the Working Alliance Inventory. Psychol Assess. 1989;1:207–210.
    1. Tichenor V, Hill CE. A comparison of six measures of working alliance. Psychother Theory Res Practice. 1989;26:195–199.
    1. Busseri MAM, Tyler JDJ. Interchangeability of the Working Alliance Inventory and Working Alliance Inventory, Short Form. Psychol Assess. 2003;15:193–197.
    1. City of Vancouver. Housing and Homelessness Strategy 2012–2021. Vancouver, BC: City of Vancouver; 2011. .
    1. Tsemberis SJ. Housing First: The Pathways Model to End Homelessness for People with Mental Illness and Addiction. Hazelden: Center City, MN; 2010.
    1. Schutt RK, Goldfinger SM. Housing preferences and perceptions of health and functioning among homeless mentally ill persons. Psychiatr Serv. 1996;47:381–386.
    1. Schutt RK, Goldfinger SM. Research in Community and Mental Health, Volume 11. Emerald Group Publishing Limited: Morrissey JP. Bingley; 2000. The contingent rationality of housing preferences: Homeless mentally ill persons' housing choices before and after housing experience; pp. 131–156.
    1. Levitt AJ, Jost JJ, Mergl KA, Hannigan A, DeGenova J, Chung SY. Impact of chronically street homeless tenants in congregate supportive housing. Am J Orthopsychiatry. 2012;82:413–420. doi: 10.1111/j.1939-0025.2012.01164.x.
    1. Kertesz SG, Crouch K, Milby JB, Cusimano RE, Schumacher JE. Housing first for homeless persons with active addiction: are we overreaching? Milbank Q. 2009;87:495–534. doi: 10.1111/j.1468-0009.2009.00565.x.

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