Persistence of immune responses after a single dose of Novartis meningococcal serogroup A, C, W-135 and Y CRM-197 conjugate vaccine (Menveo®) or Menactra® among healthy adolescents
Christopher J Gill, Roger Baxter, Alessandra Anemona, Giuseppe Ciavarro, Peter Dull, Christopher J Gill, Roger Baxter, Alessandra Anemona, Giuseppe Ciavarro, Peter Dull
Abstract
The persistence of human bactericidal activity (hSBA) responses in adolescents was assessed 22 months after vaccination with one dose of Menveo® (MenACWY-CRM; Novartis) or Menactra® (MCV4) (sanofi pasteur). The proportion of subjects with hSBA titers ≥8 was significantly higher among recipients of MenACWY-CRM than MCV4 for serogroups A, W-135 and Y.
Trial registration: ClinicalTrials.gov NCT00856297.
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Source: PubMed