Low kV and Low Concentration Contrast Agent with Iterative Reconstruction of Computed Tomography (CT) Coronary Angiography: A Preliminary Study

Hong Zhang, Yanhe Ma, Jun Lyu, Yapeng Yang, Wei Yuan, Zhenchun Song, Hong Zhang, Yanhe Ma, Jun Lyu, Yapeng Yang, Wei Yuan, Zhenchun Song

Abstract

BACKGROUND The aim of this study was to evaluate the image quality and radiation dose of CT coronary angiography (CTCA) with low kV, low concentration contrast agent, and iterative reconstruction. MATERIAL AND METHODS Ninety cases were randomly divided into 3 groups according to contrast agent concentration: group A 270 mg/ml (100 kV), group B 350 mg/ml (120 kV), and group C 370 mg/ml (120 kV), with 30 cases per group. Tube current was 200-250 mAs. Collimator width was 128×0.6 mm. Rotation speed was 0.27 s. The CT value of the left and right coronary arteries and the ascending aortic root was measured. The SNR and CNR of the images were calculated to evaluate the image quality objectively. The CTDI, DLP, and contrast injection were recorded. RESULTS There were no significant differences in sex, age, weight, height, and BMI among the 3 groups. There was no statistically significant difference between left and right coronary artery and ascending aortic root CT value, background noise, SNR, and CNR. Compared to B and C, the ED in group A decreased by about 27.58% and 28.21%, respectively. The total amount of iodine in group A was decreased by about 21.27% and 24.83%, respectively compared with groups B and C. CONCLUSIONS Low kV and low concentration contrast agent combined with iterative reconstruction for CTCA imaging produced image quality consistent with that of conventional CTCA and significantly reduced the dosage of the radiation and injected iodine.

Figures

Figure 1
Figure 1
CTCA image with 100 kV, 270 mg/ml contrast agent. (A) VR; (B–D) CPR image of LAD, LCx, and RCA, respectively.

References

    1. Zhang LJ, Wang Y, Schoepf UJ, et al. Image quality, radiation dose, and diagnostic accuracy of prospectively ECG-triggered high-pitch coronary CT angiography at 70 kVp in a clinical setting: Comparison with invasive coronary angiography. Eur Radiol. 2016;26:797–806.
    1. Qi L, Wu SY, Meinel FG, et al. Prospectively ECG-triggered high-pitch 80 kVp coronary computed tomography angiography with 30 mL of 270 mg I/mL contrast material and iterative reconstruction. Acta Radiol. 2016;57:287–94.
    1. Hou Y, Ma Y, Fan W, et al. Diagnostic accuracy of low-dose 256-slice multi-detector coronary CT angiography using iterative reconstruction in patients with suspected coronary artery disease. Eur Radiol. 2014;24:3–11.
    1. Layritz C, Schmid J, Achenbach S, et al. Accuracy of prospectively ECG-triggered very low-dose coronary dual-source CT angiography using iterative reconstruction for the detection of coronary artery stenosis: Comparison with invasive catheterization. Eur Heart J Cardiovasc Imaging. 2014;15:1238–45.
    1. Oda S, Weissman G, Vembar M, Weigold WG. Iterative model reconstruction: improved image quality of low-tube-voltage prospective ECG-gated coronary CT angiography images at 256-slice CT. Eur J Radiol. 2014;83:1408–15.
    1. Wang Z, Chen Y, Wang Y, et al. Feasibility of low-dose contrast medium high pitch CT angiography for the combined evaluation of coronary, head and neck arteries. PLoS One. 2014;9:e90268.
    1. Wang R, Schoepf UJ, Wu R, et al. Image quality and radiation dose of low dose coronary CT angiography in obese patients: Sinogram affirmed iterative reconstruction versus filtered back projection. Eur J Radiol. 2012;81:3141–45.
    1. Yuki H, Utsunomiya D, Funama Y, et al. Value of knowledge-based iterative model reconstruction in low-kV 256-slice coronary CT angiography. J Cardiovasc Comput Tomogr. 2014;8:115–23.
    1. Wang R, Schoepf UJ, Wu R, et al. Diagnostic accuracy of coronary CT angiography: Comparison of filtered back projection and iterative reconstruction with different strengths. J Comput Assist Tomogr. 2014;38:179–84.
    1. Iyama Y, Nakaura T, Kidoh M, et al. Submillisievert radiation dose coronary CT Angiography: Clinical impact of the knowledge-based iterative model reconstruction. Acad Radiol. 2016;23:1393–401.
    1. Lu L, Xu K, Wang C, et al. [Reduced-dose mode with low-voltage and low contrast agent in coronary artery CT angiography – a preliminary study]. Zhonghua Yi Xue Za Zhi. 2014;94:2251–55. [in Chinese]
    1. Lei ZQ, Han P, Xu HB, et al. Correlation between low tube voltage in dual source CT coronary artery imaging with image quality and radiation dose. J Huazhong Univ Sci Technolog Med Sci. 2014;34:616–20.
    1. Schoenhagen P, Baker ME. Our preoccupation with ultra-low dose radiation exposure. Low contrast resolution and cardiovascular CT imaging. J Cardiovasc Comput Tomogr. 2014;8:426–28.
    1. Eisentopf J, Achenbach S, Ulzheimer S, et al. Low-dose dual-source CT angiography with iterative reconstruction for coronary artery stent evaluation. JACC Cardiovasc Imaging. 2013;6:458–65.
    1. Schuhbaeck A, Achenbach S, Layritz C, et al. Image quality of ultra-low radiation exposure coronary CT angiography with an effective dose <0.1 mSv using high-pitch spiral acquisition and raw data-based iterative reconstruction. Eur Radiol. 2013;23:597–606.

Source: PubMed

Patrocinadores e Colaboradores

Condições médicas

Intervenções de drogas

3
Se inscrever