Pericapsular Nerve Group (PENG) Block versus Supra-Inguinal Fascia Iliaca Compartment Block for Total Hip Arthroplasty: A Randomized Clinical Trial

Yong Seon Choi, Kwan Kyu Park, Bora Lee, Won Seok Nam, Do-Hyeong Kim, Yong Seon Choi, Kwan Kyu Park, Bora Lee, Won Seok Nam, Do-Hyeong Kim

Abstract

This study compared the effects of the pericapsular nerve group (PENG) block and supra-inguinal fascia iliaca compartment block (FICB) on postoperative analgesia and quadriceps strength following total hip arthroplasty under general anesthesia. A total of 58 patients were randomized to receive either PENG block (PENG group) or supra-inguinal FICB (FICB group) following anesthetic induction. The primary outcomes were the postoperative pain scores. Patients were randomized to receive either PENG block or supra-inguinal FICB following anesthetic induction. Pain scores at rest and with movement were assessed preoperatively, at the postanesthesia care unit (only at rest), and at 6, 24, 36, and 48 h postoperatively. Opioid consumption was also assessed for 48 h postoperatively. Quadriceps strength measurements were performed preoperatively, at 6, 24, and 36 h postoperatively. In total, 54 patients completed the study: 27 in the PENG group and 27 in the FICB group. Despite lower pain scores at rest in the PENG group at postoperative 6 and 24 h, there were no significant differences in the pain scores at rest and during movement between the two groups during postoperative 48 h in the linear mixed model analysis (p = 0.079 and p = 0.323, respectively). Cumulative opioid consumption up to postoperative 48 h was also similar in the two groups (p = 0.265). The changes in quadriceps strength measurements in the operative leg and the nonoperative leg were not significantly different between the groups (p = 0.513 and p = 0.523, respectively). The PENG block may have similar analgesic efficacy to the supra-inguinal FICB. No difference was detected in the quadriceps strength between the patients receiving these two blocks.

Keywords: arthroplasty; hip surgery; nerve block; postoperative analgesia.

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Pericapsular nerve group (PENG) block: AIIS, anterior inferior iliac spine; IPE, iliopubic eminence; PT, psoas tendon.
Figure 2
Figure 2
Flow diagram of patient selection: ASA, American Society of Anesthesiologists; FICB, supra-inguinal fascia iliaca compartment block; PCA, patient-controlled analgesia; PENG, pericapsular nerve group block.
Figure 3
Figure 3
Pain intensity and opioid consumption: (A) NRS pain scores at rest over time. Data are expressed as mean ± standard deviation; (B) total opioid use over time. The bar chart displays the mean cumulative opioid consumption with standard deviation (error bars) at 6, 24, and 48 h following surgery. FICB, supra-inguinal fascia iliaca compartment block; NRS, numeric rating scale; PACU, postanesthesia care unit; PENG, pericapsular nerve group block.

References

    1. Hojer Karlsen A.P., Geisler A., Petersen P.L., Mathiesen O., Dahl J.B. Postoperative pain treatment after total hip arthroplasty: A systematic review. Pain. 2015;156:8–30. doi: 10.1016/j.pain.0000000000000003.
    1. Pepper A.M., Mercuri J.J., Behery O.A., Vigdorchik J.M. Total Hip and Knee Arthroplasty Perioperative Pain Management: What Should Be in the Cocktail. JBJS Rev. 2018;6:e5. doi: 10.2106/JBJS.RVW.18.00023.
    1. Bugada D., Bellini V., Lorini L.F., Mariano E.R. Update on Selective Regional Analgesia for Hip Surgery Patients. Anesthesiol. Clin. 2018;36:403–415. doi: 10.1016/j.anclin.2018.04.001.
    1. Shariat A.N., Hadzic A., Xu D., Shastri U., Kwofie K., Gandhi K., McCally C.M., Gratenstein K., Vandepitte C., Gadsden J., et al. Fascia lliaca block for analgesia after hip arthroplasty: A randomized double-blind, placebo-controlled trial. Reg. Anesth. Pain Med. 2013;38:201–205. doi: 10.1097/AAP.0b013e31828a3c7c.
    1. Hebbard P., Ivanusic J., Sha S. Ultrasound-guided supra-inguinal fascia iliaca block: A cadaveric evaluation of a novel approach. Anaesthesia. 2011;66:300–305. doi: 10.1111/j.1365-2044.2011.06628.x.
    1. Vermeylen K., Soetens F., Leunen I., Hadzic A., Van Boxtael S., Pomés J., Prats Galino A., Van de Velde M., Neyrinck A., Sala Blanch X. The effect of the volume of supra-inguinal injected solution on the spread of the injectate under the fascia iliaca: A preliminary study. J. Anesth. 2018;32:908–913. doi: 10.1007/s00540-018-2558-9.
    1. Vermeylen K., Desmet M., Leunen I., Soetens F., Neyrinck A., Carens D., Caerts B., Seynaeve P., Hadzic A., Van de Velde M. Supra-inguinal injection for fascia iliaca compartment block results in more consistent spread towards the lumbar plexus than an infra-inguinal injection: A volunteer study. Reg. Anesth. Pain Med. 2019;44:483–491. doi: 10.1136/rapm-2018-100092.
    1. Desmet M., Vermeylen K., Van Herreweghe I., Carlier L., Soetens F., Lambrecht S., Croes K., Pottel H., Van de Velde M. A Longitudinal Supra-Inguinal Fascia Iliaca Compartment Block Reduces Morphine Consumption After Total Hip Arthroplasty. Reg. Anesth. Pain Med. 2017;42:327–333. doi: 10.1097/AAP.0000000000000543.
    1. Birnbaum K., Prescher A., Hessler S., Heller K.D. The sensory innervation of the hip joint--an anatomical study. Surgical and radiologic anatomy. SRA. 1997;19:371–375. doi: 10.1007/BF01628504.
    1. Short A.J., Barnett J.J.G., Gofeld M., Baig E., Lam K., Agur A.M.R., Peng P.W.H. Anatomic Study of Innervation of the Anterior Hip Capsule: Implication for Image-Guided Intervention. Reg. Anesth. Pain Med. 2018;43:186–192. doi: 10.1097/AAP.0000000000000701.
    1. Girón Arango L., Peng P.W.H., Chin K.J., Brull R., Perlas A. Pericapsular Nerve Group (PENG) Block for Hip Fracture. Reg. Anesth. Pain Med. 2018;43:859–863. doi: 10.1097/AAP.0000000000000847.
    1. Shin S., Min K.T., Shin Y.S., Joo H.M., Yoo Y.C. Finding the ‘ideal’ regimen for fentanyl-based intravenous patient-controlled analgesia: How to give and what to mix? Yonsei Med. J. 2014;55:800–806. doi: 10.3349/ymj.2014.55.3.800.
    1. Nielsen S., Degenhardt L., Hoban B., Gisev N. A synthesis of oral morphine equivalents (OME) for opioid utilisation studies. Pharmacoepidemiol. Drug Saf. 2016;25:733–737. doi: 10.1002/pds.3945.
    1. Maffiuletti N.A. Assessment of hip and knee muscle function in orthopaedic practice and research. J. Bone Jt. Surg. Am. Vol. 2010;92:220–229. doi: 10.2106/JBJS.I.00305.
    1. Gasanova I., Alexander J.C., Estrera K., Wells J., Sunna M., Minhajuddin A., Joshi G.P. Ultrasound-guided suprainguinal fascia iliaca compartment block versus periarticular infiltration for pain management after total hip arthroplasty: A randomized controlled trial. Reg. Anesth. Pain Med. 2019;44:206–211. doi: 10.1136/rapm-2018-000016.
    1. Johnson R.L., Amundson A.W., Abdel M.P., Sviggum H.P., Mabry T.M., Mantilla C.B., Schroeder D.R., Pagnano M.W., Kopp S.L. Continuous Posterior Lumbar Plexus Nerve Block Versus Periarticular Injection with Ropivacaine or Liposomal Bupivacaine for Total Hip Arthroplasty: A Three-Arm Randomized Clinical Trial. J. Bone Jt. Surg. Am. Vol. 2017;99:1836–1845. doi: 10.2106/JBJS.16.01305.
    1. Rowbotham M.C. What is a “clinically meaningful” reduction in pain? Pain. 2001;94:131–132. doi: 10.1016/S0304-3959(01)00371-2.
    1. Lin D.Y., Morrison C., Brown B., Saies A.A., Pawar R., Vermeulen M., Anderson S.R., Lee T.S., Doornberg J., Kroon H.M., et al. Pericapsular nerve group (PENG) block provides improved short-term analgesia compared with the femoral nerve block in hip fracture surgery: A single-center double-blinded randomized comparative trial. Reg. Anesth. Pain Med. 2021;46:398–403. doi: 10.1136/rapm-2020-102315.
    1. Pascarella G., Costa F., Del Buono R., Pulitano R., Strumia A., Piliego C., De Quattro E., Cataldo R., Agro F.E., Carassiti M., et al. Impact of the pericapsular nerve group (PENG) block on postoperative analgesia and functional recovery following total hip arthroplasty: A randomised, observer-masked, controlled trial. Anaesthesia. 2021;76:1492–1498. doi: 10.1111/anae.15536.
    1. Aliste J., Layera S., Bravo D., Jara A., Munoz G., Barrientos C., Wulf R., Branez J., Finlayson R.J., Tran Q. Randomized comparison between pericapsular nerve group (PENG) block and suprainguinal fascia iliaca block for total hip arthroplasty. Reg. Anesth. Pain Med. 2021;46:874–878. doi: 10.1136/rapm-2021-102997.
    1. Gerhardt M., Johnson K., Atkinson R., Snow B., Shaw C., Brown A., Vangsness C.T., Jr. Characterisation and classification of the neural anatomy in the human hip joint. Hip Int. J. Clin. Exp. Res. Hip Pathol. Ther. 2012;22:75–81. doi: 10.5301/HIP.2012.9042.
    1. Tran J., Agur A., Peng P. Is pericapsular nerve group (PENG) block a true pericapsular block? Reg. Anesth. Pain Med. 2019;44:257. doi: 10.1136/rapm-2018-100278.
    1. Panzenbeck P., von Keudell A., Joshi G.P., Xu C.X., Vlassakov K., Schreiber K.L., Rathmell J.P., Lirk P. Procedure-specific acute pain trajectory after elective total hip arthroplasty: Systematic review and data synthesis. Br. J. Anaesth. 2021;127:110–132. doi: 10.1016/j.bja.2021.02.036.
    1. Yu H.C., Moser J.J., Chu A.Y., Montgomery S.H., Brown N., Endersby R.V.W. Inadvertent quadriceps weakness following the pericapsular nerve group (PENG) block. Reg. Anesth. Pain Med. 2019;44:611–613. doi: 10.1136/rapm-2018-100354.
    1. Giron-Arango L., Tran J., Peng P.W. Reply to Aydin et al.: A Novel Indication of Pericapsular Nerve Group Block: Surgical Anesthesia for Vein Ligation and Stripping. J. Cardiothorac. Vasc. Anesth. 2020;34:845–846. doi: 10.1053/j.jvca.2019.10.027.
    1. Anger M., Valovska T., Beloeil H., Lirk P., Joshi G.P., Van de Velde M., Raeder J., the PROSPECT Working Group. the European Society of Regional Anaesthesia and Pain Therapy PROSPECT guideline for total hip arthroplasty: A systematic review and procedure-specific postoperative pain management recommendations. Anaesthesia. 2021;76:1082–1097. doi: 10.1111/anae.15498.
    1. Abdallah F.W., McCartney C.J.L. Recommendations for total hip arthroplasty pain management: What’s old, what’s new and what continues to be missing? Anaesthesia. 2021;76:1018–1020. doi: 10.1111/anae.15502.
    1. Alakkad H., Naeeni A., Chan V.W., Abbas S., Oh J., Ami N., Ng J., Gardam M., Brull R. Infection related to ultrasound-guided single-injection peripheral nerve blockade: A decade of experience at toronto Western hospital. Reg. Anesth. Pain Med. 2015;40:82–84. doi: 10.1097/AAP.0000000000000181.
    1. Jimenez-Almonte J.H., Wyles C.C., Wyles S.P., Norambuena-Morales G.A., Baez P.J., Murad M.H., Sierra R.J. Is Local Infiltration Analgesia Superior to Peripheral Nerve Blockade for Pain Management After THA: A Network Meta-analysis. Clin. Orthop. Relat. Res. 2016;474:495–516. doi: 10.1007/s11999-015-4619-9.

Source: PubMed

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