[Incidence and preventability of haemorrhagic strokes. Results of the Ebrictus register]
A Gonzalez-Henares, J L Clua-Espuny, V F Gil-Guillen, A Panisello-Tafalla, M L Queralt-Tomas, R Ripolles-Vicente, C Lopez-Pablo, J Lucas-Noll, Equipo de Investigacion Ebrictus Equipo de Investigacion Ebrictus, A Gonzalez-Henares, J L Clua-Espuny, V F Gil-Guillen, A Panisello-Tafalla, M L Queralt-Tomas, R Ripolles-Vicente, C Lopez-Pablo, J Lucas-Noll, Equipo de Investigacion Ebrictus Equipo de Investigacion Ebrictus
Abstract
Aim: To determine the population incidence of intracerebral haemorrhage and its preventable incidence, associated risk factors and prognosis of death and disability.
Subjects and methods: We examined a sample of 240 consecutive patients with a first episode of intracerebral haemorrhage between 1st April 2006 and 30th June 2015. The main variables are: NIHSS scale, comorbidity, pharmacological information, Barthel index, Rankin scale, time within therapeutic window, prognosis and destination on hospital discharge. The 'unnecessarily premature and sanitarily avoidable mortality' (MIPSE) classification was applied to define the cases as 'preventable incidence'.
Results: The rate of population incidence of haemorrhagic cerebrovascular disease was 23.5 cases per 100,000 inhabitants/year; an exponential increase occurred from the age of 55 years in males and 75 years in females. The rate ratio was 0.682. The preventable incidence would account for 66.6% of all the cases in those under 75 years of age and 22.7% in those aged 75 or over. The chances of survival and functional autonomy were significantly lower in females, and age, anticoagulant treatment, the presence of polymedication and treatment with serotonin reuptake inhibitor antidepressants were factors that were independent of the prognosis.
Conclusions: The incidence of haemorrhagic cerebrovascular disease does not appear to be modified within the period, but just the opposite occurs with the factors associated according to sex and age. According to the MIPSE classification, the preventability of haemorrhagic cerebrovascular disease could be as high as 36%.
Source: PubMed