Cohort Study in Primary Health Care on the Evolution of Patients with Prediabetes (PREDAPS): basis and methodology
Rosario Serrano, F Javier García-Soidán, Alicia Díaz-Redondo, Sara Artola, Josep Franch, Javier Díez, Lourdes Carrillo, Patxi Ezkurra, J Manuel Millaruelo, Mateu Seguí, F Javier Sangrós, Juan Martínez-Candela, Pedro Muñoz, Albert Goday, Enrique Regidor, Grupo de Estudio PREDADS, Margarita Alonso, Beatriz Álvarez, Fernando Álvarez, J Carlos Álvarez, J Joaquín Antón, Oriol Armengol, Luis Ávila, Carmen Babace, Lourdes Barutell, Ma Jesús Bedoya, Belén Benito, Marti Birules, Concepción Blanco, Ma Isabel Bobé, Carmen Boente, Antonia Borras, Remei Bosch, Ma Jesús Brito, Pilar Buil, J José Cabré, Francisco Carbonell, Francisco Carramiñana, Ana Casorrán, Rafael Colas, Blanca Cordero, Xavier Cos, Gabriel Cuatrecasas, Cristina De Castro, Manuel De la Flor, Carlos de la Sen, Rosa Marde de Miguel, A María de Santiago, Mercedes del Castillo, David Domínguez, Carmen Durán, Manuel Ferreiro, Javier Gamarra, Francisco García, Luis García-Giralda, Ma Teresa Gijón, Ángel Gómez, María del Carmen Gómez, J Carles González, María González, Esteban Granero, Ángela Trinidad Gutiérrez, Félix Gutiérrez, Luisa Gutiérrez, M Angel Gutiérrez, Ana María Hernández, Mercedes Ibáñez, Rosario Iglesias, Dimas Igual, Ángeles Jurado, Rafael Llanes, Flora López, Regina López, Riánsares López, Ángela Lorenzo, Carmen Losada, Ramón Macía, Fernando Malo, José Mancera, Ma José Mansilla, Ma Teresa Marín, José Luis Martín, F Javier Martínez, Juan Martínez, Ma del Carmen Martínez, Rosario Martínez, Anna Massana, Manel Mata, Ma Soledad Mayayo, José Javier Mediavilla, Luis Mendo, Alicia Monzón, Ana Moreno, Xavier Mundet, Teresa Mur, Emma Navarro, Jorge Navarro, Pedro Nogales, J Carlos Obaya, Cristina Oria, Francisco Javier Ortega, Francisca Paniagua, José Luis Pardo, Francisco Carlos Pérez, Pedro Pablo Pérez, Raquel Plana, Nuria Porta, Santiago Poveda, Luis Prieto, Ramón Pujol, Sol Reixa, Jazmín Ripoll, Antonio Rodríguez, J José Rodríguez, Ma Angeles Rollán, María Teresa Rollán, Laura Romera, Pilar Roura, Jóse Félix Rubio, Antonio Ruiz, Irene Ruiz, Manuel Antonio Ruiz, Isabel Saenz, Julio Sagredo, Alejandro Salanova, L Gabriel Sánchez, Manuel Sánchez, Gloria Sanz, Dulce Suárez, Eduard Tarragó, Jesús Torrecilla, José Luis Torres, Mercè Villaro, Rosario Serrano, F Javier García-Soidán, Alicia Díaz-Redondo, Sara Artola, Josep Franch, Javier Díez, Lourdes Carrillo, Patxi Ezkurra, J Manuel Millaruelo, Mateu Seguí, F Javier Sangrós, Juan Martínez-Candela, Pedro Muñoz, Albert Goday, Enrique Regidor, Grupo de Estudio PREDADS, Margarita Alonso, Beatriz Álvarez, Fernando Álvarez, J Carlos Álvarez, J Joaquín Antón, Oriol Armengol, Luis Ávila, Carmen Babace, Lourdes Barutell, Ma Jesús Bedoya, Belén Benito, Marti Birules, Concepción Blanco, Ma Isabel Bobé, Carmen Boente, Antonia Borras, Remei Bosch, Ma Jesús Brito, Pilar Buil, J José Cabré, Francisco Carbonell, Francisco Carramiñana, Ana Casorrán, Rafael Colas, Blanca Cordero, Xavier Cos, Gabriel Cuatrecasas, Cristina De Castro, Manuel De la Flor, Carlos de la Sen, Rosa Marde de Miguel, A María de Santiago, Mercedes del Castillo, David Domínguez, Carmen Durán, Manuel Ferreiro, Javier Gamarra, Francisco García, Luis García-Giralda, Ma Teresa Gijón, Ángel Gómez, María del Carmen Gómez, J Carles González, María González, Esteban Granero, Ángela Trinidad Gutiérrez, Félix Gutiérrez, Luisa Gutiérrez, M Angel Gutiérrez, Ana María Hernández, Mercedes Ibáñez, Rosario Iglesias, Dimas Igual, Ángeles Jurado, Rafael Llanes, Flora López, Regina López, Riánsares López, Ángela Lorenzo, Carmen Losada, Ramón Macía, Fernando Malo, José Mancera, Ma José Mansilla, Ma Teresa Marín, José Luis Martín, F Javier Martínez, Juan Martínez, Ma del Carmen Martínez, Rosario Martínez, Anna Massana, Manel Mata, Ma Soledad Mayayo, José Javier Mediavilla, Luis Mendo, Alicia Monzón, Ana Moreno, Xavier Mundet, Teresa Mur, Emma Navarro, Jorge Navarro, Pedro Nogales, J Carlos Obaya, Cristina Oria, Francisco Javier Ortega, Francisca Paniagua, José Luis Pardo, Francisco Carlos Pérez, Pedro Pablo Pérez, Raquel Plana, Nuria Porta, Santiago Poveda, Luis Prieto, Ramón Pujol, Sol Reixa, Jazmín Ripoll, Antonio Rodríguez, J José Rodríguez, Ma Angeles Rollán, María Teresa Rollán, Laura Romera, Pilar Roura, Jóse Félix Rubio, Antonio Ruiz, Irene Ruiz, Manuel Antonio Ruiz, Isabel Saenz, Julio Sagredo, Alejandro Salanova, L Gabriel Sánchez, Manuel Sánchez, Gloria Sanz, Dulce Suárez, Eduard Tarragó, Jesús Torrecilla, José Luis Torres, Mercè Villaro
Abstract
The PREDAPS study aims to determine the risk of developing diabetes and the risk of vascular complications in patients with prediabetes and identify factors associated with those risks. It is a prospective observational study of a cohort of 1184 subjects with prediabetes and another cohort of 838 subjects with no alterations in glucose metabolism. The data at baseline were obtained from patients attending primary care centers in Spain throughout 2012. Subjects with prediabetes were classified into three groups: those who had only altered the fasting blood glucose levels -between 100 and 125mg/dl-, those who had only altered the HbA1c level -between 5.7 and 6.4% - and those who had altered both parameters. Information on sociodemographic characteristics, personal and family history, lifestyle and drug therapy was obtained from medical records and the interview with the doctor in the consultation. It was also performed a physical examination to determine weight, height, waist circumference and blood pressure were performed and blood and urine analysis. The PREDAPS study may help to reduce uncertainty in individual prevention strategies in subjects with prediabetes. Annual monitoring of patients recruited for five years will enable to know the risk of developing diabetes type 2 and the risk of macro-and microvascular complications in the three groups of subjects with prediabetes and determine the factors associated with those risks.
Source: PubMed