Development and psychometric validation of the Chinese version of Skindex-29 and Skindex-16

Zehui He, Chuanjian Lu, Mary-Margaret Chren, Zhongzhao Zhang, Yan Li, Xiaojia Ni, Henry A Buchtel V, Paul F Ryan, Guo-Zheng Li, Zehui He, Chuanjian Lu, Mary-Margaret Chren, Zhongzhao Zhang, Yan Li, Xiaojia Ni, Henry A Buchtel V, Paul F Ryan, Guo-Zheng Li

Abstract

Background: Dermatological disease significantly affects patient's health-related quality of life (HrQoL). Skindex is one of the most frequently used dermatology-specific HrQoL measures. Currently no Chinese version of Skindex is available. The aim of this study was to translate and culturally adapt Skindex-29 and Skindex-16 into Chinese, and to evaluate their reliability and validity.

Methods: Translation and cultural adaption were performed following guidelines for cross-cultural adaption of health-related quality of life measures. Subsequently, a cross-sectional study was conducted in which patients with dermatological disease (n = 225) were enrolled. The Chinese version of Skindex-29 and Skindex-16 and Dermatology Life Quality Index (DLQI) were completed. Reliability was evaluated with internal consistency using Cronbach's alpha. Validity was evaluated using known-groups validity, convergent validity and factor structure validity.

Results: There were both seven items of Skindex-29 and Skindex-16 requiring a second forward- and backward- translation to achieve the final satisfactory Chinese version. The internal consistency reliability was high (range of Cronbach's alpha for the scales of Skindex-29 0.85-0.97, Skindex-16 0.86-0.96). Known-group validity was demonstrated by higher scores from patients with inflammatory dermatosis than from patients with isolated skin lesions (P < 0.05). Evidence of factor structure validity of the Skindex-29 and Skindex-16 was demonstrated by both exploratory factor analysis that accounted for 68.66% and 77.78% of the total variance, respectively, and confirmatory factor analysis with acceptable fitness into the expected three-factor structure.

Conclusion: This study has developed semantically equivalent translations of Skindex-29 and Skindex-16 into Chinese. The evaluation of the instruments' psychometric properties shows they have substantial evidence of reliability and validity for use as HrQoL instruments in Chinese patients with dermatological disease.

Figures

Figure 1
Figure 1
Box plot of Skindex-29 total scorein patients with various grades of bothered by the side-effects of treatment.
Figure 2
Figure 2
The three-factor model for Skindex-29 obtained from confirmatory factor analysis.
Figure 3
Figure 3
The three-factor model for Skindex-16 obtained from confirmatory factor analysis.

References

    1. Aaronson N, Alonso J, Burnam A, Lohr KN, Patrick DL, Perrin E, Stein RE. Assessing health status and quality-of-life instruments: attributes and review criteria. Qual Life Res. 2002;11:193–205. doi: 10.1023/A:1015291021312.
    1. De Korte J, Mombers FM, Sprangers MA, Bos JD. The suitability of quality of life questionnaires for psoriasis research: a systematic literature review. Arch Dermatol. 2002;138:1221–1227. doi: 10.1001/archderm.138.9.1221.
    1. Chren MM, Lasek RJ, Quinn LM, Mostow EN, Zyzanski SJ. Skindex, a quality-of-life measure for patients with skin disease: reliability, validity and responsiveness. J Invest Dermatol. 1996;107:707–713. doi: 10.1111/1523-1747.ep12365600.
    1. Chren MM, Lasek RJ, Flocke SA, Zyzanski SJ. Improved discriminative and evaluative capability of a refined version of Skindex, a quality-of-life instrument for patients with skin diseases. Arch Dermatol. 1997;133:1433–1440. doi: 10.1001/archderm.1997.03890470111018.
    1. Chren MM, Lasek RJ, Quinn LM, Covinsky KE. Convergent and discriminant validity of a generic and a disease-specific instrument to measure quality of life in patients with skin disease. J Invest Dermatol. 1997;108:103–107. doi: 10.1111/1523-1747.ep12285650.
    1. Chren MM, Lasek RJ, Sabay AP, Sands LP.: Measurement properties of Skindex-16: A brief quality of life measure for patients with skin diseases.J Cutan Med Surg 2001, 5(2):105–110.
    1. Both H, Essink-Bot ML, Busschbach J, Nijsten T. Critical review of generic and dermatology-specific health-related quality of life instruments. J Invest Dermatol. 2007;127:2726–2739. doi: 10.1038/sj.jid.5701142.
    1. Lee EH, Klassen AF, Nehal KS, Cano SJ, Waters J, Pusic AL. A systematic review of patient-reported outcome instruments of nonmelanoma skin cancer in the dermatologic population. J Am Acad Dermatol. 2013;69:e59–e67. doi: 10.1016/j.jaad.2012.09.017.
    1. Whited JD, Warshaw EM, Edison KE, Kapur K, Thottapurathu L, Raju S, Cook B, Engasser H, Pullen S, Parks P, Sindowski T, Motyka D, Brown R, Moritz TE, Datta SK, Chren MM, Marty L, Reda DJ. Effect of store and forward teledermatology on quality of life: a randomized controlled trial. JAMA Dermatol. 2013;149:584–591. doi: 10.1001/2013.jamadermatol.380.
    1. Guillemin F, Bonbardier C, Beaton D. Cross-cultural adaptation of health-related quality of life measures: literature review and proposed guidelines. J Clin Epidemiol. 1993;46:1417–1432. doi: 10.1016/0895-4356(93)90142-N.
    1. Finlay AY, Khan GK. Dermatology Life Quality Index (DLQI)- a simple practical measure for routine clinical use. Clin Exp Dermatol. 1994;19:210–216. doi: 10.1111/j.1365-2230.1994.tb01167.x.
    1. He Z, Lu C, Basra MK, Ou A, Yan Y, Li L. Psychometric properties of the Chinese version of Dermatology Life Quality Index (DLQI) in 851 Chinese patients with psoriasis. J Eur Acad Dermatol Venereol. 2013;27:109–115. doi: 10.1111/j.1468-3083.2011.04371.x.
    1. Basra MKA, Fenech R, Gatt RM, Salek MS, Finlay AY. The Dermatology Life Quality Index 1994–2007: a comprehensive review of validation data and clinical results. Br J Dermatol. 2008;159:997–1035.
    1. Anderson RT, Rajagopalan R: Development and validation of a quality of life instrument for cutaneous diseases.J Am Acad Dermatol 1997, 37(1):41–50.
    1. Marsh HW, Hau K-T, Grayson D. Goodness of Fit Evaluation in Structural Equation Modeling. Mahwah: Erlbaum Erlbaum Associates; 2005.
    1. Hu L, Bentler PM: Fit indices in covariance structure modeling: sensitivity to underparameterized model misspecification.Psychological Methods 1998, 3:424–453.
    1. Jones-Caballero M, Peñas PF, García-Díez A, Badía X, Chren MM. The Spanish version of Skindex-29. Int J Dermatol. 2000;39:907–912. doi: 10.1046/j.1365-4362.2000.00944.x.
    1. Aksu AE, Urer MS, Sabuncu I, Saracoglu ZN, Chren MM. Turkish version of Skindex-29. Int J Dermatol. 2007;46:350–355. doi: 10.1111/j.1365-4632.2007.03008.x.
    1. Higaki Y, Kawamoto K, Kamo T, Horikawa N, Kawashima M, Chren MM. The Japanese version of Skindex-16: a brief quality-of-life measure for patients with skin diseases. J Dermatol. 2002;29:693–698. doi: 10.1111/j.1346-8138.2002.tb00205.x.
    1. AlGhamdi KM, AlShammari SA. Arabic version of Skindex-16: translation and cultural adaptation, with assessment of reliability and validity. Int J Dermatol. 2007;46:247–252. doi: 10.1111/j.1365-4632.2007.03013.x.
    1. Lewis V, Finlay AY. 10 years experience of the Dermatology Life Quality Index (DLQI) J Investig Dermatol Symp Proc. 2004;9:169–180. doi: 10.1111/j.1087-0024.2004.09113.x.
    1. Janowski K, Steuden S, Bereza B. The Polish version of Skindex-29: psychometric properties of an instrument to measure quality of life in dermatology. Postepy Dermatol Alergol. 2014;31:12–20. doi: 10.5114/pdia.2014.40654.
    1. Abeni D, Picardi A, Pasquini P, Melchi CF, Chren MM. Further evidence of the validity and reliability of the Skindex-29: an Italian study on 2,242 dermatological outpatients. Dermatology. 2002;204:43–49. doi: 10.1159/000051809.

Source: PubMed

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