Cancer-Related Fatigue: Causes and Current Treatment Options

Melissa S Y Thong, Cornelis J F van Noorden, Karen Steindorf, Volker Arndt, Melissa S Y Thong, Cornelis J F van Noorden, Karen Steindorf, Volker Arndt

Abstract

Cancer-related fatigue (CRF) is a problem for a significant proportion of cancer survivors during and after active cancer treatment. However, CRF is underdiagnosed and undertreated. Interventions are available for CRF although there is no gold standard. Based on current level of evidence, exercise seems to be most effective in preventing or ameliorating CRF during the active- and posttreatment phases.

Keywords: Cancer-related fatigue; Complementary and alternative medicine; Cytokines; Pharmacologic; Physical activity.

Conflict of interest statement

Melissa S.Y. Thong declares that she has no conflict of interest.

Cornelis J. F. van Noorden declares that he has no conflict of interest.

Karen Steindorf has received speaker’s honoraria from adViva Heidelberg, BIG Health Insurance (Dortmund), Preventon (Frankfurt); has received reimbursement for travel expenses from Asklepios Clinics (Hamburg), BIG Health Insurance (Dortmund), and Preventon (Frankfurt); and has received compensation from Pfizer for consulting on/writing a brochure on physical activity and cancer for breast cancer patients.

Volker Arndt declares that he has no conflict of interest.

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