Type 2 Diabetes and the Use of Real-Time Continuous Glucose Monitoring

Melanie A Jackson, Andrew Ahmann, Viral N Shah, Melanie A Jackson, Andrew Ahmann, Viral N Shah

Abstract

The role of continuous glucose monitoring (CGM) in type 1 diabetes (T1D) is well established in improving glycemic control and reducing hypoglycemia. Type 2 diabetes (T2D) is more prevalent than T1D and management of T2D is more heterogeneous, requiring treatment ranging from lifestyle modification to oral medications to intensive insulin therapy. Recent randomized controlled trials in intensively insulin-treated T2D demonstrated the efficacy and safety of real-time CGM (rtCGM) in reducing glycated hemoglobin without increasing hypoglycemia. Although evidence is limited, early studies have indicated a role for rtCGM in selected patients with non-insulin requiring T2D to improve glycemic control and/or reduce hypoglycemia. Based on literature review, we summarized current data on the use of rtCGM in T2D management and provided future research direction to generate more evidence on the utility of CGM in this population.

Keywords: Continuous glucose monitor; Glucose monitoring; Glycemic control; HbA1c; Type 2 diabetes.

Conflict of interest statement

M.A.J. reports no conflict of interests. A.A. receives research support from Dexcom and is on the advisory board for Medtronic. V.N.S. reports receiving research grants through University of Colorado from Sanofi, Eli-Lilly, NovoNordisk, vTv Therapeutics, Mylan GmbH, Dexcom, and Insulet. V.N.S. had served on advisory board for Sanofi and Medscape LLC.

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Source: PubMed

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