Diabetes in Hispanic American youth: prevalence, incidence, demographics, and clinical characteristics: the SEARCH for Diabetes in Youth Study

Jean M Lawrence, Elizabeth J Mayer-Davis, Kristi Reynolds, Jennifer Beyer, David J Pettitt, Ralph B D'Agostino Jr, Santica M Marcovina, Giuseppina Imperatore, Richard F Hamman, SEARCH for Diabetes in Youth Study Group, Jean M Lawrence, Elizabeth J Mayer-Davis, Kristi Reynolds, Jennifer Beyer, David J Pettitt, Ralph B D'Agostino Jr, Santica M Marcovina, Giuseppina Imperatore, Richard F Hamman, SEARCH for Diabetes in Youth Study Group

Abstract

Objective: To report the 2001 prevalence and 2002-2005 incidence of type 1 and type 2 diabetes in Hispanic American youth and to describe the demographic, clinical, and behavioral characteristics of these youth.

Research design and methods: Data from the SEARCH for Diabetes in Youth Study, a population-based multicenter observational study of youth aged 0-19 years with physician-diagnosed diabetes, were used to estimate the prevalence and incidence of type 1 and type 2 diabetes. Information obtained by questionnaire, physical examination, and blood and urine collection was analyzed to describe the characteristics of youth who completed a study visit.

Results: Among Hispanic American youth, type 1 diabetes was more prevalent than type 2 diabetes, including in youth aged 10-19 years. There were no significant sex differences in type 1 or type 2 diabetes prevalence. The incidence of type 2 diabetes for female subjects aged 10-14 years was twice that of male subjects (P < 0.005), while among youth aged 15-19 years the incidence of type 2 diabetes exceeded that of type 1 diabetes for female subjects (P < 0.05) but not for male subjects. Poor glycemic control, defined as A1C >or=9.5%, as well as high LDL cholesterol and triglycerides were common among youth aged >or=15 years with either type of diabetes. Forty-four percent of youth with type 1 diabetes were overweight or obese.

Conclusions: Factors such as poor glycemic control, elevated lipids, and a high prevalence of overweight and obesity may put Hispanic youth with type 1 and type 2 diabetes at risk for future diabetes-related complications.

Figures

Figure 1
Figure 1
2001 prevalence (A and B) and 2002–2005 incidence (C and D) of diabetes among Hispanic youth, by diabetes type, age-group, and sex.
Figure 2
Figure 2
Overweight and obesity among Hispanic 2001 prevalent and 2002–2005 incident cohorts of youth with diabetes, by diabetes type, age-group, and sex (A and B: Female subjects; C and D: Male subjects).

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