Case series: Antidepressant effects of low-affinity and low-trapping NMDA receptor antagonists did not predict response to ketamine in seven subjects

Lauren Lepow, David A Luckenbaugh, Lawrence Park, Ioline D Henter, Carlos A Zarate Jr, Lauren Lepow, David A Luckenbaugh, Lawrence Park, Ioline D Henter, Carlos A Zarate Jr

No abstract available

Keywords: Antidepressant; Depression; Glutamate; Ketamine; Memantine; NMDA receptor antagonist.

Conflict of interest statement

All other authors have no conflict of interest to disclose, financial or otherwise.

Figures

Fig. 1

Each line represents one subject and each point represents that subject's maximum percent change in Montgomery-Asberg Depression Rating Scale (MADRS) from baseline anytime at or after 230 mins. Percent change in score for subject AZD6765-A reflects Hamilton Depression Rating Scale (HAM-D) score rather than MADRS score.