Effects of Interactive Video Game-Based Exercise on Balance in Diabetic Patients with Peripheral Neuropathy: An Open-Level, Crossover Pilot Study

Erica Shih-Wei Hung, Shih-Ching Chen, Fan-Chien Chang, Yaojung Shiao, Chih-Wei Peng, Chien-Hung Lai, Erica Shih-Wei Hung, Shih-Ching Chen, Fan-Chien Chang, Yaojung Shiao, Chih-Wei Peng, Chien-Hung Lai

Abstract

Purpose. This study evaluated the effects of interactive video game-based (IVGB) exercise on balance in diabetic patients with peripheral neuropathy. Materials and Methods. Twenty-four patients were randomly assigned to two groups (12 participants per group). Group A received IVGB training for the first 6 weeks, with no exercise in the subsequent 6 weeks. Group B had no exercise for the first 6 weeks and then underwent IVGB training in the subsequent 6 weeks. For all participants, the Modified Falls Efficacy Scale (MFES), Time Up and Go (TUG) test, Berg Balance Scale (BBS), and Unipedal Stance Test (UST) were employed at weeks 0, 6, and 12 of the experiment. Results. BBS, right-leg UST, and TUG test scores significantly improved after IVGB intervention, whereas MFES and left-leg UST tended to improve after IVGB intervention. Conclusions. This study revealed that 6-week balance-based exercise training using the IVGB system exerted positive effects on functional balance in patients with diabetic peripheral neuropathy (DPN).

Figures

Figure 1
Figure 1
Flow chart of patient recruitment in this study.
Figure 2
Figure 2
Protocol of IVGB intervention. (a) IVGB system set-up. (b) Task 1: stepping exercise. (c) Task 2: hamsters game. (d) Task 3: drumming game.
Figure 3
Figure 3
Combined changes in variable outcomes of the intervention phase in Groups A and B versus combined changes in variable outcomes of the control phase in Groups A and B. TUG test, Timed Up and Go test. BBS, Berg Balance Scale. The time/score differences for TUG test and BBS in the intervention phase were calculated by subtracting the scores/time for week 6 from those for week 0 in Group A and subtracting the scores/time for week 12 from those for week 6 in Group B, whereas their time/score differences in the control phase were calculated by subtracting the scores/time for week 12 from those for week 6 in Group A and subtracting the scores/time for week 6 from those for week 0 in Group B. ∗ P < 0.05, difference between mean increase in participants with intervention and those without intervention as determined by the Mann–Whitney U test.

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Source: PubMed

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