Prevalence of self-reported knee symptoms and management strategies among elderly individuals from Frederiksberg municipality: protocol for a prospective and pragmatic Danish cohort study

Elisabeth Marie Ginnerup-Nielsen, Marius Henriksen, Robin Christensen, Berit Lilienthal Heitmann, Roy Altman, Lyn March, Anthony Woolf, Hanne Karlsen, Henning Bliddal, Elisabeth Marie Ginnerup-Nielsen, Marius Henriksen, Robin Christensen, Berit Lilienthal Heitmann, Roy Altman, Lyn March, Anthony Woolf, Hanne Karlsen, Henning Bliddal

Abstract

Introduction: The Global Burden of Disease 2010 study ranked osteoarthritis (OA) as a leading cause of years lived with disability. With an ageing population, increasing body weight and sedentary lifestyle, a substantial increase especially in knee OA (KOA) is expected. Management strategies for KOA include non-pharmacological, pharmacological and surgical interventions. Meanwhile, over-the-counter pain medications have been discredited as they are associated with several risks with long-term usage. By consequence, the use of exercise and all sorts of complementary and alternative medicine (CAM) for joint pain has increased. The available self-management strategies are plenty, but there is no overview of their use at a population level and whether they are used along with doctors' prescriptions or replace these. The aim of this study is to estimate the population incidence of developing knee symptoms and analyse the association between (and impact of) the use of self-reported preventive measures and knee symptoms.

Methods and analysis: This prospective cohort study pragmatically recruits individuals from the municipality of Frederiksberg, Denmark. All citizens aged 60-69 years old will be contacted annually for 10 years and asked to participate in a web-based survey. The major outcomes are self-reported knee symptoms and their association with use of various management strategies, including use of non-pharmacological treatments and CAM. Secondary outcomes include the influence of treatments on use of healthcare system and surgical procedures. Descriptive and analytic statistics (eg, logistic regression) will be used to provide summaries about the sample and observations made and the associations between self-management and development of knee symptoms.

Ethics and dissemination: This study can be implemented without permission from the Health Research Ethics Committee. Permission has been obtained from the Danish Data Protection Agency. Study findings will be disseminated in peer-reviewed journals and presented at relevant conferences.

Trial registration number: NCT03472300.

Keywords: chronic pain; complementary therapies; knee; osteoarthritis; surveys and questionnaires.

Conflict of interest statement

Competing interests: None declared.

© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

References

    1. Cross M, Smith E, Hoy D, et al. . The global burden of hip and knee osteoarthritis: estimates from the global burden of disease 2010 study. Ann Rheum Dis 2014;73:1323–30. 10.1136/annrheumdis-2013-204763
    1. Peat G, McCarney R, Croft P. Knee pain and osteoarthritis in older adults: a review of community burden and current use of primary health care. Ann Rheum Dis 2001;60:91–7. 10.1136/ard.60.2.91
    1. Apold H, Meyer HE, Nordsletten L, et al. . Risk factors for knee replacement due to primary osteoarthritis, a population based, prospective cohort study of 315,495 individuals. BMC Musculoskelet Disord 2014;15:217 10.1186/1471-2474-15-217
    1. Järvholm B, Lewold S, Malchau H, et al. . Age, bodyweight, smoking habits and the risk of severe osteoarthritis in the hip and knee in men. Eur J Epidemiol 2005;20:537–42. 10.1007/s10654-005-4263-x
    1. Christensen P, Henriksen M, Bartels EM, et al. . Long-term weight-loss maintenance in obese patients with knee osteoarthritis: a randomized trial. Am J Clin Nutr 2017;106:ajcn158543–63. 10.3945/ajcn.117.158543
    1. Kroon FPB, van der Burg LRA, Buchbinder R, et al. . Self‐management education programmes for osteoarthritis. Cochrane Database Syst Rev 2014;(1):CD008963 10.1002/14651858.CD008963.pub2
    1. Moss-Morris R, Weinman J, Petrie K, et al. . The revised illness perception questionnaire (IPQ-R). Psychol Health 2002;17:1–16. 10.1080/08870440290001494
    1. Glattacker M, Heyduck K, Meffert C, et al. . Illness beliefs, treatment beliefs and information needs as starting points for patient information: the evaluation of an intervention for patients with depression. J Clin Psychol Med Settings 2018;25:316–33. 10.1007/s10880-018-9551-1
    1. Damman W, Liu R, Kaptein AA, et al. . Illness perceptions and their association with 2 year functional status and change in patients with hand osteoarthritis. Rheumatology 2018;57:2190–9. 10.1093/rheumatology/key231
    1. Manniche C, Bentzen L, Hesselsøe G, et al. . Clinical trial of intensive muscle training for chronic low back pain. The Lancet 1988;332:1473–6. 10.1016/S0140-6736(88)90944-0
    1. Bliddal H, Leeds AR, Christensen R. Osteoarthritis, obesity and weight loss: evidence, hypotheses and horizons - a scoping review. Obes Rev 2014;15:578–86. 10.1111/obr.12173
    1. Bliddal H, Leeds AR, Stigsgaard L, et al. . Weight loss as treatment for knee osteoarthritis symptoms in obese patients: 1-year results from a randomised controlled trial. Ann Rheum Dis 2011;70:1798–803. 10.1136/ard.2010.142018
    1. Gudzune KA, Doshi RS, Mehta AK, et al. . Efficacy of commercial weight-loss programs: an updated systematic review. Ann Intern Med 2015;162:501–12. 10.7326/M14-2238
    1. Johns DJ, Hartmann-Boyce J, Jebb SA, et al. . Diet or exercise interventions vs combined behavioral weight management programs: a systematic review and meta-analysis of direct comparisons. J Acad Nutr Diet 2014;114:1557–68. 10.1016/j.jand.2014.07.005
    1. Zenk S, Tarlov E, Wing C, et al. . Long-Term weight loss effects of a behavioral weight management program: does the community food environment matter? Int J Environ Res Public Health 2018;15:211 10.3390/ijerph15020211
    1. Mbizo J, Okafor A, Sutton MA, et al. . Complementary and alternative medicine use by normal weight, overweight, and obese patients with arthritis or other musculoskeletal diseases. J Altern Complement Med 2016;22:227–36. 10.1089/acm.2014.0390
    1. Phang JK, Kwan YH, Goh H, et al. . Complementary and alternative medicine for rheumatic diseases: a systematic review of randomized controlled trials. Complement Ther Med 2018;37:143–57. 10.1016/j.ctim.2018.03.003
    1. Al-Windi A. Predictors of herbal medicine use in a Swedish health practice. Pharmacoepidemiol Drug Saf 2004;13:489–96. 10.1002/pds.901
    1. Biltoft-Jensen AA, Hindborg H, Christensen T, et al. . De fleste får NOK vitaminer OG mineraler fra kosten alene. E-artikel Fra Dtu Fødevareinstitutet 2016;2016:1–13.
    1. Clarke TC, Black LI, Stussman BJ, et al. . Trends in the use of complementary health approaches among adults: United States, 2002–2012. Natl Health Stat Report
    1. Djuv A, Nilsen OG, Steinsbekk A. The co-use of conventional drugs and herbs among patients in Norwegian general practice: a cross-sectional study. BMC Complement Altern Med 2013;13:295 10.1186/1472-6882-13-295
    1. Nielsen MW, Hansen EH, Rasmussen NK. Use of natural medicines in the Danish population: a national cross-sectional survey. Ann Pharmacother 2005;39:1534–8. 10.1345/aph.1G119
    1. Schnabel K, Binting S, Witt CM, et al. . Use of complementary and alternative medicine by older adults--a cross-sectional survey. BMC Geriatr 2014;14:38 10.1186/1471-2318-14-38
    1. Jong MC, van de Vijver L, Busch M, et al. . Integration of complementary and alternative medicine in primary care: what do patients want? Patient Educ Couns 2012;89:417–22. 10.1016/j.pec.2012.08.013
    1. van Saase JL, van Romunde LK, Cats A, et al. . Epidemiology of osteoarthritis: Zoetermeer survey. Comparison of radiological osteoarthritis in a Dutch population with that in 10 other populations. Ann Rheum Dis 1989;48:271–80. 10.1136/ard.48.4.271
    1. Badley EM, Tennant A. Changing profile of joint disorders with age: findings from a postal survey of the population of Calderdale, West Yorkshire, United Kingdom. Ann Rheum Dis 1992;51:366–71. 10.1136/ard.51.3.366
    1. statistik D. Statistisk Årbog 2017, 2017. Available:
    1. Willis GB. Cognitive interviewing: a tool for improving questionnaire design. Sage Publications, 2004.
    1. EuroQol Group EuroQol--a new facility for the measurement of health-related quality of life. Health Policy 1990;16:199–208. 10.1016/0168-8510(90)90421-9
    1. Broadbent E, Petrie KJ, Main J, et al. . The brief illness perception questionnaire. J Psychosom Res 2006;60:631–7. 10.1016/j.jpsychores.2005.10.020
    1. Roos EM, Roos HP, Lohmander LS, et al. . Knee Injury and Osteoarthritis Outcome Score (KOOS)--development of a self-administered outcome measure. J Orthop Sports Phys Ther 1998;28:88–96. 10.2519/jospt.1998.28.2.88
    1. de Wit MPT, Berlo SE, Aanerud GJ, et al. . European League against rheumatism recommendations for the inclusion of patient representatives in scientific projects. Ann Rheum Dis 2011;70:722–6. 10.1136/ard.2010.135129
    1. Vandenbroucke JP, et al. Strengthening the reporting of observational studies in epidemiology (STROBE): explanation and elaboration. Ann Intern Med 2007;147:W–94. 10.7326/0003-4819-147-8-200710160-00010-w1

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