Relationship between mood disturbance and sleep quality in oncology outpatients at the initiation of radiation therapy

Abstract

Purpose of the research: The purpose of this study was to describe the occurrence of significant mood disturbance and evaluate for differences in sleep quality among four mood groups (i.e., neither anxiety nor depression, only anxiety, only depression, anxiety and depression) prior to the initiation of radiation therapy (RT).

Methods and sample: Patients (n=179) with breast, prostate, lung, and brain cancer were evaluated prior to the initiation of RT using the Pittsburgh Sleep Quality Index (PSQI), the Center for Epidemiological Studies Depression Scale, and the Spielberger State Anxiety Inventory. Differences in sleep disturbance among the four mood groups were evaluated using analyses of variance.

Key results: While 38% of the patients reported some type of mood disturbance, 57% of the patients reported sleep disturbance. Patients with clinically significant levels of anxiety and depression reported the highest levels of sleep disturbance.

Conclusions: Overall, oncology patients with mood disturbances reported more sleep disturbance than those without mood disturbance. Findings suggest that oncology patients need to be assessed for mood and sleep disturbances.

Copyright © 2009 Elsevier Ltd. All rights reserved.

Figures

Figure 1

Differences in mean global Pittsburgh Sleep Quality Index (PSQI) scores for the total sample and the four mood groups. Values are plotted as means ± standard deviations. Post hoc contrasts demonstrated that the NEITHER group had significantly lower scores than the other three mood groups and that the ANX group had significantly lower scores than the BOTH group but significantly higher than the NEITHER group (all p

Figure 2

Profiles of the mean subscale and global scores from the Pittsburgh Sleep Quality Index (PSQI) for each of the mood groups. Higher PSQI scores indicate higher levels of sleep disturbance.