Consistent Detection of 2019 Novel Coronavirus in Saliva

Kelvin Kai-Wang To, Owen Tak-Yin Tsang, Cyril Chik-Yan Yip, Kwok-Hung Chan, Tak-Chiu Wu, Jacky Man-Chun Chan, Wai-Shing Leung, Thomas Shiu-Hong Chik, Chris Yau-Chung Choi, Darshana H Kandamby, David Christopher Lung, Anthony Raymond Tam, Rosana Wing-Shan Poon, Agnes Yim-Fong Fung, Ivan Fan-Ngai Hung, Vincent Chi-Chung Cheng, Jasper Fuk-Woo Chan, Kwok-Yung Yuen, Kelvin Kai-Wang To, Owen Tak-Yin Tsang, Cyril Chik-Yan Yip, Kwok-Hung Chan, Tak-Chiu Wu, Jacky Man-Chun Chan, Wai-Shing Leung, Thomas Shiu-Hong Chik, Chris Yau-Chung Choi, Darshana H Kandamby, David Christopher Lung, Anthony Raymond Tam, Rosana Wing-Shan Poon, Agnes Yim-Fong Fung, Ivan Fan-Ngai Hung, Vincent Chi-Chung Cheng, Jasper Fuk-Woo Chan, Kwok-Yung Yuen

Abstract

The 2019 novel coronavirus (2019-nCoV) was detected in the self-collected saliva of 91.7% (11/12) of patients. Serial saliva viral load monitoring generally showed a declining trend. Live virus was detected in saliva by viral culture. Saliva is a promising noninvasive specimen for diagnosis, monitoring, and infection control in patients with 2019-nCoV infection.

Keywords: 2019 novel coronavirus; COVID-19; diagnostics; saliva; transmission; viral load.

© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Figures

Figure 1.
Figure 1.
Saliva viral load in patients with 2019 novel coronavirus infection. For this figure, specimens with undetected viral load were assigned a value of 101.

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Source: PubMed

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