A retrospective study comparing analgesic efficacy of ultrasound-guided serratus anterior plane block versus intravenous fentanyl infusion in patients with multiple rib fractures

Sandeep Diwan, Abhijit Nair, Sandeep Diwan, Abhijit Nair

Abstract

Background and aims: Inadequately managed pain due to multiple rib fractures (MRFs) can lead to atelectasis, pneumonia, prolonged ICU stay thereby leads to significant morbidity, morbidity and cost of treatment. Opioids, non-steroidal anti-inflammatory drugs and regional anaesthesia techniques like thoracic epidural or paravertebral blocks, intercostal nerve blocks are used to manage pain. Serratus anterior plane block (SAPB) is an ultrasound (US) guided interfascial plane block which has been used in managing pain due to MRFs. In this retrospective study, we compared analgesic efficacy and 24 hr fentanyl consumption in patients with MRFs who were managed with continuous SAPB versus patients who were managed with fentanyl infusion alone.

Material and methods: After Institutional Ethics Committee approval, we retrospectively collected data of 72 patients (38 in SAPB group and 34 in fentanyl group). Demographic data, VAS scores and 24 hrs fentanyl consumption was analysed in both groups.

Results: There were statistically significant lower pain scores in patients of SAPB group when compared to that of fentanyl group (p=0.001) and in 24 hrs fentanyl consumption in patients who received continuous SAPB versus that in fentanyl group(p=0.001). No complications were observed in patients who received US guided SAPB.

Conclusion: US guided SAPB is an opioid sparing, effective interfascial plane block which is safe and should be considered early in all patients who sustain MRFs. Continuous SAPB by placing a catheter can provide pain relief for longer duration, facilitate early mobilization, physiotherapy and early ICU discharge.

Keywords: Fentanyl; fracture; nerve block; pain relief; ribs; serratus anterior; ultrasound.

Conflict of interest statement

There are no conflicts of interest.

Copyright: © 2021 Journal of Anaesthesiology Clinical Pharmacology.

Figures

Figure 1
Figure 1
Showing USG guided serratus anterior plane block. (Blue arrows- needle, SAM- serratus anterior muscle, R5- fifth rib, pink arrow- pleura)
Figure 2
Figure 2
Shows comparison of VAS score for 1st 24 hrs in both groups. The figure is of a comparative line graph of means + 95% confidence interval in every 6 hrs

References

    1. Tulay CM, Yaldiz S, Bilge A. Do we really know the duration of pain after rib fracture.? Kardiochir Torakochirurgia Pol. 2018;15:147–50.
    1. Witt CE, Bulger EM. Comprehensive approach to the management of the patient with multiple rib fractures: A review and introduction of a bundled rib fracture management protocol. Trauma Surg Acute Care Open. 2017;2:e000064.
    1. Martin TJ, Eltorai AS, Dunn R, Varone A, Joyce MF, Kheirbek T, et al. Clinical management of rib fractures and methods for prevention of pulmonary complications: A review. Injury. 2019;50:1159–65.
    1. Marasco S, Lee G, Summerhayes R, Fitzgerald M, Bailey M. Quality of life after major trauma with multiple rib fractures. Injury. 2015;46:61–5.
    1. Battle CE, Hutchings H, Evans PA. Risk factors that predict mortality in patients with blunt chest wall trauma: A systematic review and meta-analysis. Injury. 2012;43:8–17.
    1. Karadayi S, Nadir A, Sahin E, Celik B, Arslan S, Kaptanoglu M. An analysis of 214 cases of rib fractures. Clinics (Sao Paulo) 2011;66:449–51.
    1. Talbot BS, Gange CP, Jr, Chaturvedi A, Klionsky N, Hobbs SK, Chaturvedi A. Traumatic rib injury: Patterns, imaging pitfalls, complications, and treatment. Radiographics. 2017;37:628–51.
    1. Dehghan N, de Mestral C, McKee MD, Schemitsch EH, Nathens A. Flail chest injuries: A review of outcomes and treatment practices from the National Trauma Data Bank. J Trauma Acute Care Surg. 2014;76:462–8.
    1. Kieninger AN, Bair HA, Bendick PJ, Howells GA. Epidural versus intravenous pain control in elderly patients with rib fractures. Am J Surg. 2005;189:327–30.
    1. Van Vledder MG, Kwakernaak V, Hagenaars T, Van Lieshout EM, Verhofstad MHJ South West Netherlands Trauma Region Study Group. Patterns of injury and outcomes in the elderly patient with rib fractures: A multicenter observational study. Eur J Trauma Emerg Surg. 2019;45:575–83.
    1. Lin FC, Li RY, Tung YW, Jeng KC, Tsai SC. Morbidity, mortality, associated injuries, and management of traumatic rib fractures. J Chin Med Assoc. 2016;79:329–34.
    1. Peek J, Beks RB, Kingma BF, Marsman M, Ruurda JP, Houwert RM, et al. Epidural analgesia for severe chest trauma: An analysis of current practice on the efficacy and safety. Crit Care Res Pract. 2019;2019:4837591. doi: 10.1155/2019/4837591.
    1. Holcomb J, McMullin N, Kozar R, Lygas M, Moore F. Morbidity from rib fractures increases after age 45. J Am Coll Surg. 2003;196:549–55.
    1. Southgate SJ, Herbst MK. StatPearls [Internet] Treasure Island (FL): StatPearls Publishing; 2019. [Last accessed on 2019 Aug 04]. Ultrasound guided serratus anterior blocks. [Updated 2019 Mar 19] Available from:
    1. Karmakar M, Ho A. Acute pain management of patients with multiple fractured ribs. J Trauma. 2003;54:615–25.
    1. Malchow RJ, Black IH. The evolution of pain management in the critically ill trauma patient: Emerging concepts from the global war on terrorism. Crit Care Med. 2008;36(Suppl):S346–57.
    1. Benyamin R, Trescot AM, Datta S, Buenaventura R, Adlaka R, Sehgal N, et al. Opioid complications and side effects. Pain Physician. 2008;11(Suppl):S105–20.
    1. Porreca F, Ossipov MH. Nausea and vomiting side effects with opioid analgesics during treatment of chronic pain: Mechanisms, implications, and management options. Pain Med. 2009;10:654–62.
    1. Thiruvenkatarajan V, Cruz Eng H, Adhikary SD. An update on regional analgesia for rib fractures. Curr Opin Anaesthesiol. 2018;31:601–7.
    1. May L, Hillermann C, Patil S. Rib fracture management. BJA Educ. 2016;16:26–32.
    1. Agamohammdi D, Montazer M, Hoseini M, Haghdoost M, Farzin H. A comparison of continuous thoracic epidural analgesia with bupivacaine versus bupivacaine and dexmedetomidine for pain control in patients with multiple rib fractures. Anesth Pain Med. 2018;8:e60805.
    1. Hashemzadeh S, Hashemzadeh K, Hosseinzadeh H, Aligholipour Maleki R, Golzari SE. Comparison thoracic epidural and intercostal block to improve ventilation parameters and reduce pain in patients with multiple rib fractures. J Cardiovasc Thorac Res. 2011;3:87–91.
    1. Malekpour M, Hashmi A, Dove J, Torres D, Wild J. Analgesic choice in management of rib fractures: Paravertebral block or epidural analgesia? Anesth Analg. 2017;124:1906–11.
    1. Yeying G, Liyong Y, Yuebo C, Yu Z, Guangao Y, Weihu M, et al. Thoracic paravertebral block versus intravenous patient-controlled analgesia for pain treatment in patients with multiple rib fractures. J Int Med Res. 2017;45:2085–91.
    1. Truitt MS, Murry J, Amos J, Lorenzo M, Mangram A, Dunn E, et al. Continuous intercostal nerve blockade for rib fractures: Ready for primetime. Trauma. 2011;71:1548–52.
    1. Hwang EG, Lee Y. Effectiveness of intercostal nerve block for management of pain in rib fracture patients. J Exerc Rehabil. 2014;10:241–4.
    1. Blanco R, Parras T, McDonnell JG, Prats-Galino A. Serratus plane block: A novel ultrasound- guided thoracic wall nerve block. Anaesthesia. 2013;68:1107–13.
    1. Biswas A, Castanov V, Li Z, Perlas A, Kruisselbrink R, Agur A, et al. Serratus plane block: A cadaveric study to evaluate optimal injectate spread. Reg Anesth Pain Med. 2018;43:854–8.
    1. Kunhabdulla NP, Agarwal A, Gaur A, Gautam SK, Gupta R, Agarwal A. Serratus anterior plane block for multiple rib fractures. Pain Physician. 2014;17:E553–5.
    1. Durant E, Dixon B, Luftig J, Mantuani D, Herring A. Ultrasound-guided serratus plane block for ED rib fracture pain control. Am J Emerg Med. 2017;35:197.e3-e6.

Source: PubMed

Подписаться