Risk factors for perineal trauma in the primiparous population during non-operative vaginal delivery

Joanna C D'Souza, Ash Monga, Douglas G Tincello, Joanna C D'Souza, Ash Monga, Douglas G Tincello

Abstract

Introduction and hypothesis: Obstetric anal sphincter injuries (OASIS) are more common in the primiparous population, especially during operative vaginal delivery (OVD). It would therefore be interesting to establish what factors influence the risk of OASIS when adjusting for the risk bias of OVD.

Methods: Retrospective analysis of prospectively collected data from the maternity database at University of Southampton NHS Foundation Trust of primiparous women sustaining OASIS during a singleton, term, cephalic, non-operative vaginal delivery between 2004 and 2015. A control comparison was made of women with otherwise identical birthing conditions but resulting with intact perinea, delivering between 2014 and 2015. Univariate and multivariate logistic regression compared maternal, intrapartum and neonatal factors of those sustaining OASIS with those with an intact perineum.

Results: Seven hundred fifty-six women sustaining an OASI met the criteria, and comparisons were made with a control population of 212. Those sustaining an OASI were significantly older (p < 0.001), more likely to be Asian (4.6-fold, p < 0.001) and had heavier babies, with a 3.6-fold greater proportion over 4 kg (p = 0.001). They were more likely to have delivered post-term and had longer second stages of labour (both p < 0.001). Epidural anaesthesia was associated with a 67% reduction in OASIS.

Conclusions: These findings support previous research regarding risk factors for OASIS. By controlling for bias of risk associated with operative vaginal delivery, this revealed a potential protective effect of the use of regional anaesthesia.

Keywords: Obstetric anal sphincter injuries (OASIS); Obstetric anal sphincter injury (OASI); Perineal trauma; Primiparity.

Conflict of interest statement

None.

References

    1. Frohlich J, Kettle C. Perineal care. BMJ Clin Evid. 2015;2015:1401.
    1. Gurol-Urganci I, Cromwell D, Edozien L, Mahmood TA, Adams E, Richmond D, et al. Third-and fourth-degree perineal tears among primiparous women in England between 2000 and 2012: time trends and risk factors. BJOG Int J Obstet Gynaecol. 2013;120(12):1516–1525. doi: 10.1111/1471-0528.12363.
    1. Thiagamoorthy G, Johnson A, Thakar R, Sultan A. National survey of perineal trauma and its subsequent management in the United Kingdom. Int Urogynecol J. 2014;25(12):1621–1627. doi: 10.1007/s00192-014-2406-x.
    1. Marsh F, Lynne R, Christine L, Alison W. Obstetric anal sphincter injury in the UK and its effect on bowel, bladder and sexual function. Eur J Obstet Gynecol Reprod Biol. 2011;154(2):223–227. doi: 10.1016/j.ejogrb.2010.09.006.
    1. Baghestan E, Irgens LM, Børdahl PE, Rasmussen S. Trends in risk factors for obstetric anal sphincter injuries in Norway. Obstet Gynecol. 2010;116(1):25–34. doi: 10.1097/AOG.0b013e3181e2f50b.
    1. Handa VL, Danielsen BH, Gilbert WM. Obstetric anal sphincter lacerations. Obstet Gynecol. 2001;98(2):225–230.
    1. Ampt AJ, Ford JB, Roberts CL, Morris JM. Trends in obstetric anal sphincter injuries and associated risk factors for vaginal singleton term births in New South Wales 2001–2009. Aust N Z J Obstet Gynaecol. 2013;53(1):9–16. doi: 10.1111/ajo.12038.
    1. Landy HJ, Laughon SK, Bailit J, Kominiarek MA, Gonzalez-Quintero VH, Ramirez M, et al. Characteristics associated with severe perineal and cervical lacerations during vaginal delivery. Obstet Gynecol. 2011;117(3):627. doi: 10.1097/AOG.0b013e31820afaf2.
    1. de Leeuw J, Struijk P, Vierhout M, Wallenburg H. Risk factors for third degree perineal ruptures during delivery. BJOG Int J Obstet Gynaecol. 2001;108(4):383–387. doi: 10.1111/j.1471-0528.2001.00090.x.
    1. Räisänen S, Vehviläinen-Julkunen K, Gissler M, Heinonen S. The increased incidence of obstetric anal sphincter rupture—an emerging trend in Finland. Prev Med. 2009;49(6):535–540. doi: 10.1016/j.ypmed.2009.10.005.
    1. Royal College of Obstetricians and Gynaecologists. The management of third-and fourth-degree perineal tears. Green Top Guideline, no. 29. London: RCOG; 2015.
    1. Silver FH, DeVore D, Siperko LM. Invited review: role of mechanophysiology in aging of ECM: effects of changes in mechanochemical transduction. J Appl Physiol. 2003;95(5):2134–2141. doi: 10.1152/japplphysiol.00429.2003.
    1. Cartwright R, Tikkinen K. Ethnicity and socioeconomic status are significant independent risk factors for obstetric anal sphincter injury (OASI) BJOG Int J Obstet Gynaecol. 2010;117(5):627.
    1. Deering SH, Carlson N, Stitely M, Allaire AD, Satin AJ. Perineal body length and lacerations at delivery. J Reprod Med. 2004;49(4):306–310.
    1. Prager M, Andersson KL, Stephansson O, Marchionni M, Marions L. The incidence of obstetric anal sphincter rupture in primiparous women: a comparison between two European delivery settings. Acta Obstet Gynecol Scand. 2008;87(2):209–215. doi: 10.1080/00016340701832661.
    1. Fenner DE, Hsu Y. Pathophysiology of the pelvic floor: basic physiology, effects of ageing, and menopausal changes. In: Santoro GA, Wieczorek AP, Bartram CI, editors. Pelvic floor disorders. Milano: Springer; 2010.
    1. Dahl C, Kjølhede P. Obstetric anal sphincter rupture in older primiparous women: a case-control study. Acta Obstet Gynecol Scand. 2006;85(10):1252–1258. doi: 10.1080/00016340600839890.
    1. Poen A, Felt-Bersma R, Dekker G, Deville W, Cuesta M, Meuwissen S. Third degree obstetric perineal tears: risk factors and the preventive role of mediolateral episiotomy. BJOG Int J Obstet Gynaecol. 1997;104(5):563–566. doi: 10.1111/j.1471-0528.1997.tb11533.x.

Source: PubMed

Подписаться