The Prevalence of Sarcopenia among Hunan Province Community-Dwelling Adults Aged 60 Years and Older and Its Relationship with Lifestyle: Diagnostic Criteria from the Asian Working Group for Sarcopenia 2019 Update

Jing Zhong, Wenqing Xie, Xiaoqin Wang, Xin Dong, Yihan Mo, Dan Liu, Xuemei Yao, Beibei Liu, Wenyu Deng, Yidong Su, Yusheng Li, Xiuhua Wang, Jing Zhong, Wenqing Xie, Xiaoqin Wang, Xin Dong, Yihan Mo, Dan Liu, Xuemei Yao, Beibei Liu, Wenyu Deng, Yidong Su, Yusheng Li, Xiuhua Wang

Abstract

Background and Objectives: This study aims to detect the prevalence of sarcopenia in community-dwelling older adults in Hunan Province, discuss factors related to lifestyle, and provide a reliable basis for the prevention and treatment of sarcopenia. Materials and Methods: In this study, a total of 1040 community-dwelling adults ≥ 60 years were examined for sarcopenia using a cluster stratified random sampling method, which was defined using the diagnostic criteria recommended by the Asian Working Group for Sarcopenia (AWGS) from September 2019 to March 2020. Multivariate logistic regression analysis was applied to determine the correlation between sarcopenia and smoking, drinking, nutritional status, physical activity, and sleep quality. Results: A total of 27.1% of the older adults were diagnosed with sarcopenia, with rates of 26.2% in men and 25.2% in women. Multiple logistic regression showed that advanced age (OR = 2.480, 95% CI: 1.730, 3.553), the risk of malnutrition (OR = 2.085, 95% CI: 1.440, 3.019), and malnutrition (OR = 1.212, 95% CI: 0.304, 4.834) were risk factors for sarcopenia. No falls in the previous year (OR = 0.616, 95% CI: 1.885, 1.209), normal weight (OR = 0.228, 95% CI: 0.109, 0.475), overweight (OR = 0.030, 95% CI: 0.013, 0.069), moderate physical activity (OR = 0.593, 95% CI: 0.377, 0.933), or high physical activity (OR = 0.417, 95% CI: 0.230, 0.755) were identified as protective factors for sarcopenia. Conclusions: The prevalence of sarcopenia was high among older adults in the community in Hunan Province. In addition, we found that lifestyle is an important factor in sarcopenia.

Keywords: ageing; community-dwelling older adults; lifestyle; prevalence; sarcopenia.

Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Kim S.H., Kim T.H., Hwang H.J. The relationship of physical activity (PA) and walking with sarcopenia in Korean males aged 60 years and older using the Fourth Korean National Health and Nutrition Examination Survey (KNHANES IV-2, 3), 2008-2009. Arch. Gerontol. Geriatr. 2013;56:472–477. doi: 10.1016/j.archger.2012.12.009.
    1. Noce A., Marrone G., Ottaviani E., Guerriero C., Di Daniele F., Pietroboni Zaitseva A., Di Daniele N. Uremic Sarcopenia and Its Possible Nutritional Approach. Nutrients. 2021;13:147. doi: 10.3390/nu13010147.
    1. Goodpaster B.H., Park S.W., Harris T.B., Kritchevsky S.B., Nevitt M., Schwartz A.V., Simonsick E.M., Tylavsky F.A., Visser M., Newman A.B. The loss of skeletal muscle strength, mass, and quality in older adults: The health, aging and body composition study. J. Gerontol. A Biol. Sci. Med. Sci. 2006;61:1059–1064. doi: 10.1093/gerona/61.10.1059.
    1. Sayer A.A., Syddall H., Martin H., Patel H., Baylis D., Cooper C. The developmental origins of sarcopenia. J. Nutr. Health Aging. 2008;12:427–432. doi: 10.1007/BF02982703.
    1. Rosenberg I.H. Sarcopenia: Origins and clinical relevance. Clin. Geriatr. Med. 2011;27:337–339. doi: 10.1016/j.cger.2011.03.003.
    1. Cruz-Jentoft A.J., Baeyens J.P., Bauer J.M., Boirie Y., Cederholm T., Landi F., Martin F.C., Michel J.P., Rolland Y., Schneider S.M., et al. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010;39:412–423. doi: 10.1093/ageing/afq034.
    1. Marty E., Liu Y., Samuel A., Or O., Lane J. A review of sarcopenia: Enhancing awareness of an increasingly prevalent disease. Bone. 2017;105:276–286. doi: 10.1016/j.bone.2017.09.008.
    1. Baumgartner R.N., Koehler K.M., Gallagher D., Romero L., Heymsfield S.B., Ross R.R., Garry P.J., Lindeman R.D. Epidemiology of sarcopenia among the elderly in New Mexico. Am. J. Epidemiol. 1998;147:755–763. doi: 10.1093/oxfordjournals.aje.a009520.
    1. Tarantino U., Piccirilli E., Fantini M., Baldi J., Gasbarra E., Bei R. Sarcopenia and fragility fractures: Molecular and clinical evidence of the bone-muscle interaction. J. Bone Joint Surg. Am. 2015;97:429–437. doi: 10.2106/JBJS.N.00648.
    1. Sun S., Lee H., Yim H.W., Won H.S., Ko Y.H. The impact of sarcopenia on health-related quality of life in elderly people: Korean National Health and Nutrition Examination Survey. Korean J. Intern. Med. 2019;34:877–884. doi: 10.3904/kjim.2017.182.
    1. Marcos-Pardo P.J., González-Gálvez N., López-Vivancos A., Espeso-García A., Martínez-Aranda L.M., Gea-García G.M., Orquín-Castrillón F.J., Carbonell-Baeza A., Jiménez-García J.D., Velázquez-Díaz D., et al. Sarcopenia, Diet, Physical Activity and Obesity in European Middle-Aged and Older Adults: The LifeAge Study. Nutrients. 2020;13:8. doi: 10.3390/nu13010008.
    1. Chen L.K., Woo J., Assantachai P., Auyeung T.W., Chou M.Y., Iijima K., Jang H.C., Kang L., Kim M., Kim S., et al. Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment. J. Am. Med. Dir. Assoc. 2020;21:300–307.e302. doi: 10.1016/j.jamda.2019.12.012.
    1. Li C.W., Yu K., Shyh-Chang N., Li G.X., Jiang L.J., Yu S.L., Xu L.Y., Liu R.J., Guo Z.J., Xie H.Y., et al. Circulating factors associated with sarcopenia during ageing and after intensive lifestyle intervention. J. Cachexia Sarcopenia Muscle. 2019;10:586–600. doi: 10.1002/jcsm.12417.
    1. Pourmotabbed A., Ghaedi E., Babaei A., Mohammadi H., Khazaie H., Jalili C., Symonds M.E., Moradi S., Miraghajani M. Sleep duration and sarcopenia risk: A systematic review and dose-response meta-analysis. Sleep Breath. 2020;24:1267–1278. doi: 10.1007/s11325-019-01965-6.
    1. Roberts H.C., Denison H.J., Martin H.J., Patel H.P., Syddall H., Cooper C., Sayer A.A. A review of the measurement of grip strength in clinical and epidemiological studies: Towards a standardised approach. Age Ageing. 2011;40:423–429. doi: 10.1093/ageing/afr051.
    1. Cruz-Jentoft A.J., Bahat G., Bauer J., Boirie Y., Bruyère O., Cederholm T., Cooper C., Landi F., Rolland Y., Sayer A.A., et al. Sarcopenia: Revised European consensus on definition and diagnosis. Age Ageing. 2019;48:16–31. doi: 10.1093/ageing/afy169.
    1. Guigoz Y., Vellas B., Garry P.J. Assessing the nutritional status of the elderly: The Mini Nutritional Assessment as part of the geriatric evaluation. Nutr. Rev. 1996;54:S59–S65. doi: 10.1111/j.1753-4887.1996.tb03793.x.
    1. Washburn R.A., Smith K.W., Jette A.M., Janney C.A. The Physical Activity Scale for the Elderly (PASE): Development and evaluation. J. Clin. Epidemiol. 1993;46:153–162. doi: 10.1016/0895-4356(93)90053-4.
    1. Li J. Analysis rating of sleep state of 13273 normal persons. Heath Psychol. J. 2000;8:351–353.
    1. Kim M., Won C.W. Sarcopenia in Korean Community-Dwelling Adults Aged 70 Years and Older: Application of Screening and Diagnostic Tools From the Asian Working Group for Sarcopenia 2019 Update. J. Am. Med. Dir. Assoc. 2020;21:752–758. doi: 10.1016/j.jamda.2020.03.018.
    1. Kobayashi K., Imagama S., Ando K., Machino M., Ota K., Tanaka S., Morozumi M., Kanbara S., Ito S., Ishiguro N., et al. Epidemiology and effect on physical function of osteosarcopenia in community-dwelling elderly people in Japan. Mod. Rheumatol. 2020;30:592–597. doi: 10.1080/14397595.2019.1623455.
    1. Simsek H., Meseri R., Sahin S., Kilavuz A., Bicakli D.H., Uyar M., Savas S., Sarac F., Akcicek F. Prevalence of sarcopenia and related factors in community-dwelling elderly individuals. Saudi Med. J. 2019;40:568–574. doi: 10.15537/smj.2019.6.23917.
    1. Pongchaiyakul C., Limpawattana P., Kotruchin P., Rajatanavin R. Prevalence of sarcopenia and associated factors among Thai population. J. Bone Miner. Metab. 2013;31:346–350. doi: 10.1007/s00774-013-0422-4.
    1. Han P., Zhao J., Guo Q., Wang J., Zhang W., Shen S., Wang X., Dong R., Ma Y., Kang L., et al. Incidence, Risk Factors, and the Protective Effect of High Body Mass Index against Sarcopenia in Suburb-Dwelling Elderly Chinese Populations. J. Nutr. Health Aging. 2016;20:1056–1060. doi: 10.1007/s12603-016-0704-3.
    1. Cruz-Jentoft A.J., Landi F., Schneider S.M., Zúñiga C., Arai H., Boirie Y., Chen L.K., Fielding R.A., Martin F.C., Michel J.P., et al. Prevalence of and interventions for sarcopenia in ageing adults: A systematic review. Report of the International Sarcopenia Initiative (EWGSOP and IWGS) Age Ageing. 2014;43:748–759. doi: 10.1093/ageing/afu115.
    1. Cheng Q., Zhu X., Zhang X., Li H., Du Y., Hong W., Xue S., Zhu H. A cross-sectional study of loss of muscle mass corresponding to sarcopenia in healthy Chinese men and women: Reference values, prevalence, and association with bone mass. J. Bone Miner. Metab. 2014;32:78–88. doi: 10.1007/s00774-013-0468-3.
    1. Yakabe M., Hosoi T., Akishita M., Ogawa S. Updated concept of sarcopenia based on muscle-bone relationship. J. Bone Miner. Metab. 2020;38:7–13. doi: 10.1007/s00774-019-01048-2.
    1. Woo N., Kim S.H. Sarcopenia influences fall-related injuries in community-dwelling older adults. Geriatr. Nurs. 2014;35:279–282. doi: 10.1016/j.gerinurse.2014.03.001.
    1. Gadelha A.B., Vainshelboim B., Ferreira A.P., Neri S.G.R., Bottaro M., Lima R.M. Stages of sarcopenia and the incidence of falls in older women: A prospective study. Arch. Gerontol. Geriatr. 2018;79:151–157. doi: 10.1016/j.archger.2018.07.014.
    1. Gadelha A.B., Neri S.G.R., Nóbrega O.T., Pereira J.C., Bottaro M., Fonsêca A., Lima R.M. Muscle quality is associated with dynamic balance, fear of falling, and falls in older women. Exp. Gerontol. 2018;104:1–6. doi: 10.1016/j.exger.2018.01.003.
    1. Park J.H., Cho H., Shin J.H., Kim T., Park S.B., Choi B.Y., Kim M.J. Relationship among fear of falling, physical performance, and physical characteristics of the rural elderly. Am J Phys Med Rehabil. 2014;93:379–386. doi: 10.1097/PHM.0000000000000009.
    1. Kim S.B., O′Sullivan D.M. Effects of Aqua Aerobic Therapy Exercise for Older Adults on Muscular Strength, Agility and Balance to Prevent Falling during Gait. J. Phys. Ther. Sci. 2013;25:923–927. doi: 10.1589/jpts.25.923.
    1. Lee K., Shin Y., Huh J., Sung Y.S., Lee I.S., Yoon K.H., Kim K.W. Recent Issues on Body Composition Imaging for Sarcopenia Evaluation. Korean J. Radiol. 2019;20:205–217. doi: 10.3348/kjr.2018.0479.
    1. Papa E.V., Dong X., Hassan M. Resistance training for activity limitations in older adults with skeletal muscle function deficits: A systematic review. Clin. Interv. Aging. 2017;12:955–961. doi: 10.2147/CIA.S104674.
    1. Daly R.M. Exercise and nutritional approaches to prevent frail bones, falls and fractures: An update. Climacteric. 2017;20:119–124. doi: 10.1080/13697137.2017.1286890.
    1. Eibich P., Buchmann N., Kroh M., Wagner G.G., Steinhagen-Thiessen E., Demuth I., Norman K. Exercise at Different Ages and Appendicular Lean Mass and Strength in Later Life: Results From the Berlin Aging Study II. J. Gerontol. A Biol. Sci. Med. Sci. 2016;71:515–520. doi: 10.1093/gerona/glv171.
    1. Breen L., Stokes K.A., Churchward-Venne T.A., Moore D.R., Baker S.K., Smith K., Atherton P.J., Phillips S.M. Two weeks of reduced activity decreases leg lean mass and induces "anabolic resistance" of myofibrillar protein synthesis in healthy elderly. J. Clin. Endocrinol. Metab. 2013;98:2604–2612. doi: 10.1210/jc.2013-1502.
    1. Karlsson M.K., Nordqvist A., Karlsson C. Physical activity, muscle function, falls and fractures. Food Nutr. Res. 2008;52:1920. doi: 10.3402/fnr.v52i0.1920.
    1. Hai S., Wang H., Cao L., Liu P., Zhou J., Yang Y., Dong B. Association between sarcopenia with lifestyle and family function among community-dwelling Chinese aged 60 years and older. BMC Geriatr. 2017;17:187. doi: 10.1186/s12877-017-0587-0.
    1. Lee S.Y., Tung H.H., Liu C.Y., Chen L.K. Physical Activity and Sarcopenia in the Geriatric Population: A Systematic Review. J. Am. Med. Dir. Assoc. 2018;19:378–383. doi: 10.1016/j.jamda.2018.02.003.
    1. Stenholm S., Tiainen K., Rantanen T., Sainio P., Heliövaara M., Impivaara O., Koskinen S. Long-term determinants of muscle strength decline: Prospective evidence from the 22-year mini-Finland follow-up survey. J. Am. Geriatr. Soc. 2012;60:77–85. doi: 10.1111/j.1532-5415.2011.03779.x.
    1. Xu W., Chen T., Cai Y., Hu Y., Fan L., Wu C. Sarcopenia in Community-Dwelling Oldest Old Is Associated with Disability and Poor Physical Function. J. Nutr. Health Aging. 2020;24:339–345. doi: 10.1007/s12603-020-1325-4.
    1. Cerri A.P., Bellelli G., Mazzone A., Pittella F., Landi F., Zambon A., Annoni G. Sarcopenia and malnutrition in acutely ill hospitalized elderly: Prevalence and outcomes. Clin. Nutr. 2015;34:745–751. doi: 10.1016/j.clnu.2014.08.015.
    1. Woo J. Nutritional interventions in sarcopenia: Where do we stand? Curr. Opin. Clin. Nutr. Metab. Care. 2018;21:19–23. doi: 10.1097/MCO.0000000000000432.
    1. Bosaeus I., Rothenberg E. Nutrition and physical activity for the prevention and treatment of age-related sarcopenia. Proc. Nutr. Soc. 2016;75:174–180. doi: 10.1017/S002966511500422X.
    1. Franzke B., Neubauer O., Cameron-Smith D., Wagner K.H. Dietary Protein, Muscle and Physical Function in the Very Old. Nutrients. 2018;10:935. doi: 10.3390/nu10070935.
    1. Deutz N.E., Bauer J.M., Barazzoni R., Biolo G., Boirie Y., Bosy-Westphal A., Cederholm T., Cruz-Jentoft A., Krznariç Z., Nair K.S., et al. Protein intake and exercise for optimal muscle function with aging: Recommendations from the ESPEN Expert Group. Clin. Nutr. 2014;33:929–936. doi: 10.1016/j.clnu.2014.04.007.
    1. Deutz N.E., Wolfe R.R. Is there a maximal anabolic response to protein intake with a meal? Clin. Nutr. 2013;32:309–313. doi: 10.1016/j.clnu.2012.11.018.
    1. Hu X., Jiang J., Wang H., Zhang L., Dong B., Yang M. Association between sleep duration and sarcopenia among community-dwelling older adults: A cross-sectional study. Medicine. 2017;96:e6268. doi: 10.1097/MD.0000000000006268.
    1. Piovezan R.D., Abucham J., Dos Santos R.V., Mello M.T., Tufik S., Poyares D. The impact of sleep on age-related sarcopenia: Possible connections and clinical implications. Ageing Res. Rev. 2015;23:210–220. doi: 10.1016/j.arr.2015.07.003.

Source: PubMed

Спонсоры и соавторы

Заболевания

Медикаментозные вмешательства

Подписаться